Patents by Inventor Charles Jewell

Charles Jewell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Indazole derivatives as modulators of interleukin-1 receptor-associated kinase
    Patent number: 8293923
    Abstract: The present invention relates to modulators of IRAK kinases of formula (I) and provides compositions comprising such modulators, as well as methods therewith for treating IRAK-mediated or IRAK-associated conditions or diseases.
    Type: Grant
    Filed: September 7, 2007
    Date of Patent: October 23, 2012
    Assignee: Biogen Idec MA Inc.
    Inventors: Kevin Guckian, Charles Jewell, Patrick Conlon, Edward Yin Shiang Lin, Timothy Chan
  • Indazole derivatives as modulators of interleukin-1 receptor-associated kinase
    Publication number: 20110152260
    Abstract: The present invention relates to modulators of IRAK kinases of formula (I) and provides compositions comprising such modulators, as well as methods therewith for treating IRAK-mediated or IRAK-associated conditions or diseases.
    Type: Application
    Filed: September 7, 2007
    Publication date: June 23, 2011
    Applicant: Biogen Idec Ma Inc.
    Inventors: Kevin Guckian, Charles Jewell, Patrick Conlon, Edward Yin Shiang Lin, Timothy Chan
  • MODULATORS OF INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE
    Publication number: 20110021513
    Abstract: The present invention relates to modulators of IRAK kinase and provides compositions comprising such modulators, as well as methods therewith for treating conditions or diseases mediated by or associated with IRAK kinase.
    Type: Application
    Filed: September 7, 2007
    Publication date: January 27, 2011
    Applicant: Biogen Idec Ma Inc.
    Inventors: Thomas Durand-Reville, Charles Jewell, Charles Hammond, Donovan Chin
  • 5-Substituted 1,1-dioxo-'1,2,5!thiazolidine-3-one derivatives as ptpase 1b inhibitors
    Publication number: 20050090502
    Abstract: Compounds of the formula provide pharmacological agents which are inhibitors of PTPases, in particular, the compounds of formula I inhibit PTP-1B and TC PTP, and thus may be employed for the treatment of conditions associated with PTPase activity. The compounds of the present invention may also be employed for inhibition of other enzymes with a phosphotyrosine binding region such as the SH2 domain. Accordingly, the compounds of formula I may be employed for prevention or treatment of insulin resistance associated with obesity, glucose intolerance, diabetes mellitus, hypertension and ischemic diseases of the large and small blood vessels.
    Type: Application
    Filed: April 2, 2003
    Publication date: April 28, 2005
    Inventors: Gary Coppola, John Davies, Charles Jewell Jr, Yu-Chin Li, James Wareing, Donald Sperbeck, Travis Stams, Sidney Topiol, Isidoros Vlattas