Abstract: Method and systems for identifying and distinguishing subjects using a detection system comprising pooled probes are described. The pooled probes described comprise subject specific features allowing for identification and distinction of subjects in a complex sample and can be utilized in a variety of detection platforms. The methods and systems can further comprise the use of isotachophoresis to concentrate analytes in a sample.

Abstract: Method and systems for identifying and distinguishing subjects using a detection system comprising pooled probes are described. The pooled probes described comprise subject specific features allowing for identification and distinction of subjects in a complex sample and can be utilized in a variety of detection platforms. The methods and systems can further comprise the use of isotachophoresis to concentrate analytes in a sample.

Abstract: Method and systems for identifying and distinguishing subjects using a biochip are described. Biochips comprising subject specific features comprising multiple non-overlapping probes are disclosed.

Abstract: Methods and compositions for the fabrication and use of arrays are disclosed. Methods of the disclosure include separating decoded arrays, such as bead arrays, into independent sections and subsections. Methods of the disclosure can enable more economical fabrication of arrays suitable for conducting various assays, such as detection of target analytes in a sample.

Abstract: Method and systems for identifying and distinguishing subjects using a detection system comprising pooled probes are described. The pooled probes described comprise subject specific features allowing for identification and distinction of subjects in a complex sample and can be utilized in a variety of detection platforms. The methods and systems can further comprise the use of isotachophoresis to concentrate analytes in a sample.

Abstract: Method and systems for identifying and distinguishing subjects using a biochip are described. Biochips comprising subject specific features comprising multiple non-overlapping probes are disclosed.

Abstract: A method and system are provided for the simultaneous detection and identification of multiple pathogens in a patient sample. The sample is combined with microbeads, which have been injected with quantum dots or fluorescent dye and conjugated to pathogen-specific biorecognition molecules, such as antibodies and oligonucleotides. Treatment options may be determined based on the identities of the pathogens detected in the sample.

Abstract: Methods and compositions for treating, managing, and/or preventing cerebral malaria are disclosed.

Abstract: Methods and compositions for treating, managing, and/or preventing cerebral malaria are disclosed.

Abstract: A method and system are provided for the simultaneous detection and identification of multiple pathogens in a patient sample. The sample is combined with microbeads, which have been injected with quantum dots or fluorescent dye and conjugated to pathogen-specific biorecognition molecules, such as antibodies and oligonucleotides. Treatment options may be determined based on the identities of the pathogens detected in the sample.

Abstract: A folding knife having a blade-opening mechanism incorporated in the handle of the knife. The blade-opening mechanism in one form can be used to pivot the blade from the closed position to the open position by manually applying pressure to the blade-opening mechanism rather than to a portion of the blade. The blade-opening mechanism in one embodiment also can be adapted to function as a closing mechanism for pivoting the blade closed without applying pressure to the blade. In particular embodiments, the handle desirably includes a pivotable side portion that is coupled to the tang portion of the blade such that manually pivoting the side portion is effective to cause pivoting movement of the blade.

Abstract: The present disclosure concerns embodiments of an improved knife sharpener. In particular embodiments, the knife sharpener has an elongated sharpening member, which can be, for example, an abrasive sharpening rod. The sharpening rod can be made of any of various suitable materials, such as ceramic, porcelain, stone, diamond. The sharpening member extends through a sharpening guide, which is movable in both directions along the length of the sharpening member. The sharpening guide defines at least one guide slot for receiving a knife blade to be sharpened. The guide slot is configured to position a facet of the knife blade in sliding contact with the sharpening member and at a predetermined angle with respect to the sharpening member.

Abstract: In one aspect, the present disclosure concerns a folding knife having a locking mechanism coupled to the blade such that pivoting the blade from the closed position to the open position, and vice versa, causes corresponding rotation of the locking mechanism about the pivot axis of the blade. The locking mechanism is operable to selectively lock the blade in the open position and optionally to selectively lock the blade in the closed position.

Abstract: A folding knife having a blade-opening mechanism incorporated in the handle of the knife. The blade-opening mechanism in one form can be used to pivot the blade from the closed position to the open position by manually applying pressure to the blade-opening mechanism rather than to a portion of the blade. The blade-opening mechanism in one embodiment also can be adapted to function as a closing mechanism for pivoting the blade closed without applying pressure to the blade. In particular embodiments, the handle desirably includes a pivotable side portion that is coupled to the tang portion of the blade such that manually pivoting the side portion is effective to cause pivoting movement of the blade.

Abstract: The present disclosure concerns embodiments of an improved knife sharpener. In particular embodiments, the knife sharpener has an elongated sharpening member, which can be, for example, an abrasive sharpening rod. The sharpening rod can be made of any of various suitable materials, such as ceramic, porcelain, stone, diamond. The sharpening member extends through a sharpening guide, which is movable in both directions along the length of the sharpening member. The sharpening guide defines at least one guide slot for receiving a knife blade to be sharpened. The guide slot is configured to position a facet of the knife blade in sliding contact with the sharpening member and at a predetermined angle with respect to the sharpening member.