Abstract: Embodiments herein report compositions of alpha-1 antitrypsin fusion polypeptides or peptide derivatives thereof. In certain embodiments, compositions and methods relate to generating a construct of use in pharmaceutically acceptable compositions to treat a subject in need of alpha-1 antitrypsin therapy or treatment. In other embodiments, compositions and methods disclosed herein concern linking alpha-1 antitrypsin or derivative thereof to an immune fragment.

Abstract: Systems and processes for operating an intelligent automated assistant to provide extension of digital assistant services are provided. An example method includes, at an electronic device having one or more processors, receiving, from a first user, a first speech input representing a user request. The method further includes obtaining an identity of the first user; and in accordance with the user identity, providing a representation of the user request to at least one of a second electronic device or a third electronic device. The method further includes receiving, based on a determination of whether the second electronic device or the third electronic device, or both, is to provide the response to the first electronic device, the response to the user request from the second electronic device or the third electronic device. The method further includes providing a representation of the response to the first user.

Abstract: Methods and systems for depositing a layer, comprising one or more of vanadium boride and vanadium phosphide, onto a surface of a substrate and structures and devices formed using the methods are disclosed. An exemplary method includes using a deposition process. The deposition process can include providing a vanadium precursor to the reaction chamber and separately providing a reactant to the reaction chamber. Exemplary structures can include field effect transistor structures, such as gate all around structures. The layer comprising one or more of vanadium boride and vanadium phosphide can be used, for example, as barrier layers or liners, as work function layers, as dipole shifter layers, or the like.

Abstract: Systems and processes for operating an intelligent automated assistant to provide extension of digital assistant services are provided. An example method includes, at an electronic device having one or more processors, receiving, from a first user, a first speech input representing a user request. The method further includes obtaining an identity of the first user; and in accordance with the user identity, providing a representation of the user request to at least one of a second electronic device or a third electronic device. The method further includes receiving, based on a determination of whether the second electronic device or the third electronic device, or both, is to provide the response to the first electronic device, the response to the user request from the second electronic device or the third electronic device. The method further includes providing a representation of the response to the first user.

Abstract: Methods and systems for depositing vanadium nitride layers onto a surface of the substrate and structures and devices formed using the methods are disclosed. An exemplary method includes using a cyclical deposition process, depositing a vanadium nitride layer onto a surface of the substrate. The cyclical deposition process can include providing a vanadium halide precursor to the reaction chamber and separately providing a nitrogen reactant to the reaction chamber. The cyclical deposition process may desirably be a thermal cyclical deposition process.

Abstract: A transistor includes a semiconductor substrate having a first terminal and a second terminal. An interconnect structure is formed on an upper surface of the semiconductor substrate, the interconnect structure being formed of multiple layers of dielectric material and electrically conductive material. The electrically conductive material of the interconnect structure includes a pillar in electrical contact with the first terminal, a first runner electrically connected to the pillar, a tap interconnect in electrical contact with the second terminal, a second runner electrically connected to the tap interconnect, a shield structure positioned between the pillar and the tap interconnect, and a shield runner electrically connected to the shield structure, the shield runner overlying the second runner in a direction perpendicular to the upper surface of the semiconductor substrate.

Abstract: In at least one embodiment, an active noise cancellation (ANC) system is provided. An audio signal source provides an audio signal. At least one loudspeaker projects anti-noise sound within a cabin. At least one microphone provides a first error signal indicative of the noise, the audio signal, and the anti-noise sound and a second error signal indicative of an estimated anti-noise signal. At least one controller is programmed to receive the first error signal and the second error signal and to provide an estimated impulse response based at least on the first error signal and the second error signal. The at least one controller is further programmed to compare the estimated impulse response to one or more pre-stored impulse responses; and to select a first pre-stored impulse response that matches the estimated impulse response to filter one or more reference signals at an adaptive filter to generate the anti-noise signal.

Abstract: Systems and methods for monitoring the quality of water or leaks within a household plumbing system via machine learning are provided. Appliances can be connected to a plumbing system, wherein each appliance includes one or more sensors configured to output sensor data regarding a property of the water being utilized by that appliance. A processor is programmed to receive the sensor data and establish boundaries of normal operation. Then, when additional sensor data is received, the processor uses machine learning to classify that sensor data as being either within normal operation, or outside the bounds of normal operation. If the sensor data indicates the water property is outside the bounds, an output signal can be generated to inform the user.

Abstract: A computational method for determining a location and an amount of a transition metal M in surface facets of a Pt—M alloy using a density functional theory includes receiving a particle size and a surface facet distribution of the Pt—M alloy and a total concentration of M in the Pt—M alloy; calculating a total number of M atoms in the Pt—M alloy based on the particle size and the surface facet distribution of the Pt—M alloy and the total concentration of M in the Pt—M alloy; and predicting a mixing energy between Pt and at least one of the total number of M atoms in a subsurface layer of each of the surface facets of the Pt—M alloy when Pt is mixed with the at least one of the total number of M atoms.

Abstract: An electrochemical cell catalyst support includes a fibrous catalyst support material. The fibrous catalyst support material includes a mixed metal oxide material of magnesium (Mg) and titanium (Ti) with a general formula of MgaTibO5-x, where 0?x?3, and a ratio of a to b is greater than 0.01 and less than 0.8.

Abstract: The present invention provides, in various embodiments, systems and methods for robotic manipulation of a patient's anatomy, such as the uterus, during minimally invasive surgical procedures.

Abstract: The systems and methods involve a feedback application, a feedback processing application, an analytics application, and an event moderating application. The feedback application allows users to submit feedback and displays received feedback anonymously to feedback recipients. The feedback processing application anonymizes the submitted feedback and the data to be retrieved from the feedback processing application and provide the anonymized feedback and data to the feedback application. The feedback processing application includes technology to protect feedback giver's identity and increase the speed of anonymizing the feedback and data and providing the anonymized feedback and data to the feedback application. The analytics application examines user's feedback giving and receiving behavior and evaluate their feedback empathy and authenticity and their learning behavior.

Abstract: The systems and methods involve a feedback application, a feedback processing application, an analytics application, and an event moderating application. The feedback application allows users to submit feedback and displays received feedback anonymously to feedback recipients. The feedback processing application anonymizes the submitted feedback and the data to be retrieved from the feedback processing application and provide the anonymized feedback and data to the feedback application. The feedback processing application includes technology to protect feedback giver's identity and increase the speed of anonymizing the feedback and data and providing the anonymized feedback and data to the feedback application. The analytics application examines user's feedback giving and receiving behavior and evaluate their feedback empathy and authenticity and their learning behavior.

Abstract: Systems and methods for operating an event with an online conferencing component. The methods comprise: receiving, by a feedback processing system, a user input selecting an event from a plurality of scheduled events which each have an online conferencing component provided by a web conferencing service; enabling, by the feedback processing system, an electronic feedback message composing function and a numerical rating selection function for a duration of time determined based on a duration setting of a timer; performing, by the feedback processing system, the electronic feedback message composing function to compose an electronic feedback message for an individual associated with the selected event; and performing, by the feedback processing system, the numerical rating selection function to select a numerical rating for the individual associated with the selected event.

Abstract: The present invention is directed to an electronic system for the assessment of emotional state. The system allows individual employees to specify their emotions using a set of emojis. The system provides a graphical user interface that displays a list of different emotions and associated emojis that the user can select. The system allows the user to write an entry about his thoughts and emotions in conjunction with the selected emojis and send the message with the emojis to individuals with whom he chooses to share. The system provides a list of company-wide employees from which the user can select. The system receives the messages and implements data structures to process the received messages and produce individual and company-wide emotional state information.

Abstract: Systems, methods, and computer readable medium are provided that relate to improvements in digital human resources technology. An automated system can be provided in which the user can have a digital interactive private space and use the space to conduct interactive assessment of five traits and to select to collect additional data from others on the five traits about the user, and includes automated algorithms that classify and detected patterns from numerical data which for example can use interrelationships between different types of data. The system is configured to record the information in the private space, provide the assessment, and allow the user to maintain the information to be private to the user while being configured to able to be maintained to allow the user to return to the private space at a later time (as configured by an application, service, and server) to perform the interactive assessment and detection of classifications.

Abstract: The present invention is directed to an electronic system for the assessment of emotional state. The system allows individual employees to specify their emotions using a set of emojis. The system provides a graphical user interface that displays a list of different emotions and associated emojis that the user can select. The system allows the user to write an entry about his thoughts and emotions in conjunction with the selected emojis and send the message with the emojis to individuals with whom he chooses to share. The system provides a list of company-wide employees from which the user can select. The system receives the messages and implements data structures to process the received messages and produce individual and company-wide emotional state information.

Abstract: Systems and methods for operating an event with an online conferencing component. The methods comprise: receiving, by a feedback processing system, a user input selecting an event from a plurality of scheduled events which each have an online conferencing component provided by a web conferencing service; enabling, by the feedback processing system, an electronic feedback message composing function and a numerical rating selection function for a duration of time determined based on a duration setting of a timer; performing, by the feedback processing system, the electronic feedback message composing function to compose an electronic feedback message for an individual associated with the selected event; and performing, by the feedback processing system, the numerical rating selection function to select a numerical rating for the individual associated with the selected event.

Abstract: A method of gastric tube placement verification comprising the steps of: Inserting a gastric tube within the patient; Providing a colorimetric based gastric tube placement verification system for a patient gastric tube including i) a housing configured to be coupled to the gastric tube whereby stomach content aspirate can flow through an internal passage of the housing; and ii) at least one colorimetric based sensor within the housing and configured to come into contact with the patient stomach content aspirate, the least one colorimetric based sensor configures to detect a first gastric acid; Coupling the housing of the colorimetric based gastric tube placement verification system to a proximal end of the gastric tube; Aspirating stomach content of the patient whereby stomach aspirate can flow through an internal passage of the housing; and Visually inspecting at least one colorimetric based sensor within the housing for verification of proper gastric tube placement.

Abstract: Electronic systems and methods for developing a person's cognitive skills such as feedback giving skills are contemplated. The systems and methods provide a procedure through which participants follow to formulate and issue feedback to other individuals. Feedback is given through a feedback app. The systems and methods involve participation of feedback recipients and also judges. The procedure involves each feedback recipient giving a presentation in a period of time and each judge providing feedback to each presentation. The procedure is performed by executing an event which can be created from an event app provided by the system. The event app also executes the created event, and completion of the event allows the system to provide feedback results to the participants, feedback recipients, judges, and other individuals based on information received during the event. The flow of the event is also controllable from the event app.