Patents by Inventor Charles Knowles
Charles Knowles has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20260241181Abstract: Provided herein are devices, systems, and methods for implanting one or more electrode leads anchored at target tissue to deliver a stimulation to treat a disease or condition of one or more tissues. The orientation of the target tissue may be standardized by adjusting the operating table based on one or more landmarks of an x-ray image. A stimulating or marking needle assembly used to verify the placement of the one or more electrode leads may comprise a removable stylet and a needle grip defining a connection region for coupling to external device. A plurality of stimulating needles may be inserted into a patient with a needle guide to determine an optimal needle location for lead placement. Also provided herein are devices, systems, and methods for implanting one or more electrode leads without the use of a guidewire.Type: ApplicationFiled: February 19, 2026Publication date: August 20, 2026Inventors: Stefan de Wachter, Charles Knowles, Nazir-Ahmed Karbanee, Gary Moore
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Publication number: 20260183544Abstract: Provided are devices and methods for preventing an episode of incontinence in an individual in need thereof. The devices comprise a sensor and a stimulator electrode that can be implanted into the body of the individual. Once the device is implanted in the individual, the sensor of the device senses a parameter that is associated with a response from the individual that is intended to prevent an episode of incontinence. Then, the device provides an electrical stimulation using the electrode that, together with the response, helps to prevent the episode of incontinence.Type: ApplicationFiled: February 24, 2026Publication date: July 2, 2026Inventors: Timothy Denison, Stefan De Wachter, Charles Knowles, Aidan Crawley
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Publication number: 20260091228Abstract: Provided are devices and methods for treating an episode of sexual dysfunction in an individual in need thereof. The devices comprise a sensor and a stimulator electrode that can be implanted into the body of the individual. Once the device is implanted in the individual, the sensor of the device senses a parameter that is associated with an episode of sexual dysfunction. The device provides an electrical stimulation using the electrode that helps to treat the episode of sexual dysfunction.Type: ApplicationFiled: September 14, 2023Publication date: April 2, 2026Inventors: Timothy Denison, Stefan De Wachter, Charles Knowles, Aidan Crawley
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Publication number: 20260021298Abstract: Provided are devices and methods for preventing an episode of incontinence in an individual in need thereof. The devices comprise a sensor and a stimulator electrode that can be implanted into the body of the individual. Once the device is implanted in the individual, the sensor of the device senses a parameter that is associated with a response from the individual that is intended to prevent an episode of incontinence. Then, the device provides an electrical stimulation using the electrode that, together with the response, helps to prevent the episode of incontinence.Type: ApplicationFiled: July 29, 2025Publication date: January 22, 2026Inventors: Timothy Denison, Stefan De Wachter, Charles Knowles, Aidan Crawley
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Patent number: 12397156Abstract: Provided are devices and methods for preventing an episode of incontinence in an individual in need thereof. The devices comprise a sensor and a stimulator electrode that can be implanted into the body of the individual. Once the device is implanted in the individual, the sensor of the device senses a parameter that is associated with a response from the individual that is intended to prevent an episode of incontinence. Then, the device provides an electrical stimulation using the electrode that, together with the response, helps to prevent the episode of incontinence.Type: GrantFiled: June 5, 2024Date of Patent: August 26, 2025Assignee: Amber Therapeutics Holdings LimitedInventors: Timothy Denison, Stefan De Wachter, Charles Knowles, Aidan Crawley
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Publication number: 20250161668Abstract: Provided herein are devices, systems, and methods for accessing the pudendal nerve to place an electrical lead on the pudendal nerve for treatment by electrical nerve stimulation. Described herein are devices, systems, and methods for providing electrical nerve stimulation to prevent an episode of incontinence in an individual in need thereof.Type: ApplicationFiled: February 22, 2023Publication date: May 22, 2025Inventors: Charles Knowles, Stefan De Wachter
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Publication number: 20240424296Abstract: Provided are devices and methods for preventing an episode of incontinence in an individual in need thereof. The devices comprise a sensor and a stimulator electrode that can be implanted into the body of the individual. Once the device is implanted in the individual, the sensor of the device senses a parameter that is associated with a response from the individual that is intended to prevent an episode of incontinence. Then, the device provides an electrical stimulation using the electrode that, together with the response, helps to prevent the episode of incontinence.Type: ApplicationFiled: June 5, 2024Publication date: December 26, 2024Inventors: Timothy DENISON, Stefan DE WACHTER, Charles KNOWLES, Aidan CRAWLEY
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Patent number: 12064625Abstract: Provided are devices and methods for preventing an episode of incontinence in an individual in need thereof. The devices comprise a sensor and a stimulator electrode that can be implanted into the body of the individual. Once the device is implanted in the individual, the sensor of the device senses a parameter that is associated with a response from the individual that is intended to prevent an episode of incontinence. Then, the device provides an electrical stimulation using the electrode that, together with the response, helps to prevent the episode of incontinence.Type: GrantFiled: June 22, 2023Date of Patent: August 20, 2024Assignee: Amber Therapeutics LtdInventors: Timothy Denison, Stefan De Wachter, Charles Knowles, Aidan Crawley
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Patent number: 12059564Abstract: Provided are devices and methods for preventing an episode of incontinence in an individual in need thereof. The devices comprise a sensor and a stimulator electrode that can be implanted into the body of the individual. Once the device is implanted in the individual, the sensor of the device senses a parameter that is associated with a response from the individual that is intended to prevent an episode of incontinence. Then, the device provides an electrical stimulation using the electrode that, together with the response, helps to prevent the episode of incontinence.Type: GrantFiled: December 19, 2022Date of Patent: August 13, 2024Assignee: Amber Therapeutics LtdInventors: Timothy Denison, Stefan De Wachter, Charles Knowles, Aidan Crawley
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Publication number: 20230347145Abstract: Provided are devices and methods for preventing an episode of incontinence in an individual in need thereof. The devices comprise a sensor and a stimulator electrode that can be implanted into the body of the individual. Once the device is implanted in the individual, the sensor of the device senses a parameter that is associated with a response from the individual that is intended to prevent an episode of incontinence. Then, the device provides an electrical stimulation using the electrode that, together with the response, helps to prevent the episode of incontinence.Type: ApplicationFiled: June 22, 2023Publication date: November 2, 2023Inventors: Timothy DENISON, Stefan DE WACHTER, Charles KNOWLES, Aidan CRAWLEY
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Publication number: 20230130942Abstract: Provided are devices and methods for preventing an episode of incontinence in an individual in need thereof. The devices comprise a sensor and a stimulator electrode that can be implanted into the body of the individual. Once the device is implanted in the individual, the sensor of the device senses a parameter that is associated with a response from the individual that is intended to prevent an episode of incontinence. Then, the device provides an electrical stimulation using the electrode that, together with the response, helps to prevent the episode of incontinence.Type: ApplicationFiled: December 19, 2022Publication date: April 27, 2023Inventors: Timothy DENISON, Stefan DE WACHTER, Charles KNOWLES, Aidan CRAWLEY
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Patent number: 11565109Abstract: Provided are devices and methods for preventing an episode of incontinence in an individual in need thereof. The devices comprise a sensor and a stimulator electrode that can be implanted into the body of the individual. Once the device is implanted in the individual, the sensor of the device senses a parameter that is associated with a response from the individual that is intended to prevent an episode of incontinence. Then, the device provides an electrical stimulation using the electrode that, together with the response, helps to prevent the episode of incontinence.Type: GrantFiled: March 11, 2022Date of Patent: January 31, 2023Assignee: Amber Therapeutics LtdInventors: Timothy Denison, Stefan De Wachter, Charles Knowles, Aidan Crawley
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Publication number: 20220288389Abstract: Provided are devices and methods for preventing an episode of incontinence in an individual in need thereof. The devices comprise a sensor and a stimulator electrode that can be implanted into the body of the individual. Once the device is implanted in the individual, the sensor of the device senses a parameter that is associated with a response from the individual that is intended to prevent an episode of incontinence. Then, the device provides an electrical stimulation using the electrode that, together with the response, helps to prevent the episode of incontinence.Type: ApplicationFiled: March 11, 2022Publication date: September 15, 2022Inventors: Timothy DENISON, Stefan DE WACHTER, Charles KNOWLES, Aidan CRAWLEY
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Publication number: 20060131876Abstract: A preferred apparatus for connecting a fitting to a conduit section comprises a rigid insert designed to be affixed to the fitting and one or more retainers designed to fit over the external surface of the conduit section. A preferred insert includes at least two axially-spaced, raised detents. Suitable retainers include rigid, one-piece collars and clamps. An especially preferred method for connecting the coupler fittings and the section of pipe comprises the steps of positioning a one-piece collar over the external surface of the conduit section; pressing the insert into a receiving end of the conduit section; and pushing the one-piece collar along the external surface of the conduit section toward the receiving end to substantially align the one-piece collar between two axially-spaced, raised detents on the insert. Most preferably, a seal is positioned between the two axially-spaced, raised detents.Type: ApplicationFiled: February 7, 2006Publication date: June 22, 2006Applicant: Wolf Creek Company, Inc.Inventors: Charles Knowles, James Orban, Sasenjko Radzepagic
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Publication number: 20050193565Abstract: A device used in self defense comprising a ring adapted to be worn on the little finger of the user and further comprising a top and a base. The base comprises a retractable blade mounted thereto that when fully deployed extends from the base of the ring in a direction opposite from the ring finger of the user.Type: ApplicationFiled: February 18, 2005Publication date: September 8, 2005Inventor: Charles Knowles