Patents by Inventor Charles L. Bailey
Charles L. Bailey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8597932Abstract: The invention involves developing and stabilizing cultivating droplets within a matrix of a porous medium. A cultivation medium may be selected, prepared and mixed with a surfactant. Where cells are desired to be cultured in droplets, cells may be added. The mixture may be converted into cultivating droplets. The cultivating droplets may be stabilized by introducing them to a porous medium. The porous medium may contain hydrophobic particles. Stabilized, cultivating droplets having one or more cells may form an aseptic microenvironment for the concentrated growth of cells.Type: GrantFiled: May 22, 2006Date of Patent: December 3, 2013Assignee: George Mason Intellectual Properties, Inc.Inventors: Victor Morozov, Charles L. Bailey, Nikolai N. Vsevolodov
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Publication number: 20120076694Abstract: Analytes using an active assay may be detected by introducing an analyte solution containing a plurality of analytes to a lacquered membrane. The lacquered membrane may be a membrane having at least one surface treated with a layer of polymers. The lacquered membrane may be semi-permeable to nonanalytes. The layer of polymers may include cross-linked polymers. A plurality of probe molecules may be arrayed and immobilized on the lacquered membrane. An external force may be applied to the analyte solution to move the analytes towards the lacquered membrane. Movement may cause some or all of the analytes to bind to the lacquered membrane. In cases where probe molecules are presented, some or all of the analytes may bind to probe molecules. The direction of the external force may be reversed to remove unbound or weakly bound analytes. Bound analytes may be detected using known detection types.Type: ApplicationFiled: September 27, 2010Publication date: March 29, 2012Inventors: Victor Morozov, Melissa R. Evanskey, Charles L. Bailey
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Publication number: 20110105344Abstract: The invention contemplates apparatuses for recognition of proteins and other biological molecules by imaging morphology, size and distribution of crystalline and amorphous dry residues in droplets (further referred to as “crystallization patterns”) containing predetermined amount of certain crystal-forming organic compounds (reporters) to which protein to be analyzed is added. Changes in the crystallization patterns of a number of amino-acids can be used as a “signature” of a protein added. Also, changes in the crystallization patterns, as well as the character of such changes, can be used as recognition elements in analysis of protein molecules.Type: ApplicationFiled: January 19, 2011Publication date: May 5, 2011Inventors: Victor Morozov, Charles L. Bailey, Nikolai N. Vsevolodov, Adam Elliott
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Patent number: 7850915Abstract: The invention contemplates apparatuses for recognition of proteins and other biological molecules by imaging morphology, size and distribution of crystalline and amorphous dry residues in droplets (further referred to as “crystallization patterns”) containing predetermined amount of certain crystal-forming organic compounds (reporters) to which protein to be analyzed is added. Changes in the crystallization patterns of a number of amino-acids can be used as a “signature” of a protein added. Also, changes in the crystallization patterns, as well as the character of such changes, can be used as recognition elements in analysis of protein molecules.Type: GrantFiled: March 3, 2008Date of Patent: December 14, 2010Assignee: George Mason Intellectual Properties, Inc.Inventors: Victor Morozov, Charles L. Bailey, Nikolai N. Vsevolodov, Adam Elliott
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Publication number: 20100275780Abstract: The claimed invention describes methods and apparatuses for manufacturing nano-aerosols and nano-structured materials based on the neutralization of charged electrosprayed products with oppositely charged electrosprayed products. Electrosprayed products include molecular ions, nano-clusters and nano-fibers. Nano-aerosols can be generated when neutralization occurs in the gas phase. Neutralization of electrospan nano-fibers with molecular ions and charged nano-clusters may result in the formation of fibrous aerosols or free nano-mats. Nano-mats can also be produced on a suitable substrate, forming efficient nano-filters.Type: ApplicationFiled: July 8, 2010Publication date: November 4, 2010Inventors: Charles L. Bailey, Victor Morozov, Nikolai N. Vsevolodov
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Patent number: 7824927Abstract: Analytes using an active assay may be detected by introducing an analyte solution containing a plurality of analytes to a lacquered membrane. The lacquered membrane may be a membrane having at least one surface treated with a layer of polymers. The lacquered membrane may be semi-permeable to nonanalytes. The layer of polymers may include cross-linked polymers. A plurality of probe molecules may be arrayed and immobilized on the lacquered membrane. An external force may be applied to the analyte solution to move the analytes towards the lacquered membrane. Movement may cause some or all of the analytes to bind to the lacquered membrane. In cases where probe molecules are presented, some or all of the analytes may bind to probe molecules. The direction of the external force may be reversed to remove unbound or weakly bound analytes. Bound analytes may be detected using known detection types.Type: GrantFiled: April 5, 2006Date of Patent: November 2, 2010Assignee: George Mason Intellectual Properties, Inc.Inventors: Victor Morozov, Charles L. Bailey, Melissa R. Evanskey
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Patent number: 7776405Abstract: The claimed invention describes methods and apparatuses for manufacturing nano-aerosols and nano-structured materials based on the neutralization of charged electrosprayed products with oppositely charged electrosprayed products. Electrosprayed products include molecular ions, nano-clusters and nano-fibers. Nano-aerosols can be generated when neutralization occurs in the gas phase. Neutralization of electrospan nano-fibers with molecular ions and charged nano-clusters may result in the formation of fibrous aerosols or free nano-mats. Nano-mats can also be produced on a suitable substrate, forming efficient nano-filters.Type: GrantFiled: November 17, 2006Date of Patent: August 17, 2010Assignee: George Mason Intellectual Properties, Inc.Inventors: Charles L. Bailey, Victor Morozov, Nikolai N. Vsevolodov
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Publication number: 20080152233Abstract: The invention contemplates apparatuses for recognition of proteins and other biological molecules by imaging morphology, size and distribution of crystalline and amorphous dry residues in droplets (further referred to as “crystallization patterns”) containing predetermined amount of certain crystal-forming organic compounds (reporters) to which protein to be analyzed is added. Changes in the crystallization patterns of a number of amino-acids can be used as a “signature” of a protein added. Also, changes in the crystallization patterns, as well as the character of such changes, can be used as recognition elements in analysis of protein molecules.Type: ApplicationFiled: March 3, 2008Publication date: June 26, 2008Inventors: Victor Morozov, Charles L. Bailey, Nikolai N. Vsevolodov, Adam Elliott
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Patent number: 7368288Abstract: The invention contemplates a method for recognition of proteins and other biological molecules by imaging morphology, size and distribution of crystalline and amorphous dry residues in droplets (further referred to as “crystallization pattern”) containing predetermined amount of certain crystal-forming organic compounds (reporters) to which protein to be analyzed is added. It has been shown that changes in the crystallization patterns of a number of amino-acids can be used as a “signature” of a protein added. It was also found that both the character of changer in the crystallization patter and the fact of such changes can be used as recognition elements in analysis of protein molecules.Type: GrantFiled: April 5, 2006Date of Patent: May 6, 2008Assignee: George Mason Intellectual Properties, Inc.Inventors: Victor Morozov, Charles L. Bailey, Nikolai N. Vsevolodov, Adam Elliott
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Patent number: 6739000Abstract: A storable bed assembly primarily for recreational vehicles permits the lowering and raising of the bed using a pair of rear guides fixed to a wall of the recreational vehicle, and a pair of swing arm guides at the front corners of the bed frame. Linkages are provided to couple the corners of the bed frame to the guides. Counterbalancing springs in the form of compressed gas cylinders are provided to assist in raising the bed assembly to the stored position.Type: GrantFiled: April 4, 2003Date of Patent: May 25, 2004Assignee: National RV Holdings, Inc.Inventor: Charles L. Bailey
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Patent number: 6649408Abstract: The present invention comprises a novel culture method and device in which living cells are cultured in a plurality of individual microdroplets that are immobilized and isolated within a matrix of hydrophobic particles. The hydrophobic particles adhere to inoculated microdroplets of media, isolating the microdroplets in an aseptic microenvironmet. The plurality of individual microdroplets provide and optimal environment for the concentrated growth of cultured cells contained therein.Type: GrantFiled: March 14, 2001Date of Patent: November 18, 2003Assignee: George Mason UniversityInventors: Charles L. Bailey, Ken Alibek
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Publication number: 20030192120Abstract: A storable bed assembly primarily for recreational vehicles permits the lowering and raising of the bed using a pair of rear guides fixed to a wall of the recreational vehicle, and a pair of swing arm guides at the front corners of the bed frame. Linkages are provided to couple the corners of the bed frame to the guides. Counterbalancing springs in the form of compressed gas cylinders are provided to assist in raising the bed assembly to the stored position.Type: ApplicationFiled: April 4, 2003Publication date: October 16, 2003Applicant: National RV Holdings, Inc.Inventor: Charles L. Bailey
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Patent number: 6557190Abstract: A storable bed assembly primarily for recreational vehicles permits the lowering and raising of the bed using a pair of rear guides fixed to a wall of the recreational vehicle, and a pair of swing arm guides at the front corners of the bed frame. Linkages are provided to couple the corners of the bed frame to the guides. Counterbalancing springs in the form of compressed gas cylinders are provided to assist in raising the bed assembly to the stored position.Type: GrantFiled: August 31, 2001Date of Patent: May 6, 2003Assignee: National RV Holdings, Inc.Inventor: Charles L. Bailey
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Publication number: 20030041377Abstract: A storable bed assembly primarily for recreational vehicles permits the lowering and raising of the bed using a pair of rear guides fixed to a wall of the recreational vehicle, and a pair of swing arm guides at the front corners of the bed frame. Linkages are provided to couple the corners of the bed frame to the guides. Counterbalancing springs in the form of compressed gas cylinders are provided to assist in raising the bed assembly to the stored position.Type: ApplicationFiled: August 31, 2001Publication date: March 6, 2003Applicant: National RV Holdings, Inc.Inventor: Charles L. Bailey
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Publication number: 20020022265Abstract: The present invention comprises a novel culture method and device in which living cells are cultured in a plurality of individual microdroplets that are immobilized and isolated within a matrix of hydrophobic particles. The hydrophobic particles adhere to inoculated microdroplets of media, isolating the microdroplets in an aseptic microenvironmet. The plurality of individual microdroplets provide and optimal environment for the concentrated growth of cultured cells contained therein.Type: ApplicationFiled: March 14, 2001Publication date: February 21, 2002Inventors: Charles L. Bailey, Ken Alibek
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Patent number: 4355626Abstract: Door structure is provided for a wood-burning stove which is less susceptible to warping in use than a conventional flanged stove door opening. The door opening is formed by a process of cold drawing or extruding a rounded lip or flange which is integral with the stove front plate. Internal door structure provides angulation of the door with respect to the stove front plate.Type: GrantFiled: July 30, 1981Date of Patent: October 26, 1982Assignee: Eagle-Picher Industries, Inc.Inventors: Charles L. Bailey, Roy D. Baker