Patents by Inventor Charles L. Carrico
Charles L. Carrico has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9770679Abstract: The invention provides a sequential centrifuge for centrifuging discrete samples. Methods of more efficiently centrifuging discrete samples sequentially are also provided. The apparatus and methods for sequentially centrifuging discrete samples provide improved operating efficiencies over conventional batch centrifuges. Such advantages include reducing dwell time, increasing system throughput, reducing sample processing system footprint, and improving precision of the analytical process. The sequential centrifuge further provides the capability of handling critical samples without compromising the operating efficiencies achieved in centrifuging discrete samples in a sequential manner.Type: GrantFiled: September 17, 2015Date of Patent: September 26, 2017Assignee: Becton, Dickinson and CompanyInventors: William Alan Fox, Charles L. Carrico
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Patent number: 9448246Abstract: The invention provides an integrated sequential sample preparation system using a sequential centrifuge for preparing samples for analysis. Methods of more efficiently preparing discrete samples sequentially for subsequent analysis are also provided. The apparatus and methods for sequentially preparing discrete samples provide improved operating efficiencies over conventional preparation processes that use batch centrifugation systems. Such advantages include reducing dwell time, increasing system throughput, reducing sample preparation system footprint, and improving precision of the analytical process. The integrated sequential preparation system with the integrated sequential centrifuge further provides the capability of handling critical or STAT samples without compromising the operating efficiencies achieved by preparing discrete samples in a sequential manner.Type: GrantFiled: January 9, 2015Date of Patent: September 20, 2016Assignee: TriPath Imaging, Inc.Inventors: William Alan Fox, Charles L. Carrico, Jr.
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Publication number: 20160008745Abstract: The invention provides a sequential centrifuge for centrifuging discrete samples. Methods of more efficiently centrifuging discrete samples sequentially are also provided. The apparatus and methods for sequentially centrifuging discrete samples provide improved operating efficiencies over conventional batch centrifuges. Such advantages include reducing dwell time, increasing system throughput, reducing sample processing system footprint, and improving precision of the analytical process. The sequential centrifuge further provides the capability of handling critical samples without compromising the operating efficiencies achieved in centrifuging discrete samples in a sequential manner.Type: ApplicationFiled: September 17, 2015Publication date: January 14, 2016Inventors: William Alan Fox, Charles L. Carrico
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Patent number: 9211549Abstract: The invention provides a sequential centrifuge for centrifuging discrete samples. Methods of more efficiently centrifuging discrete samples sequentially are also provided. The apparatus and methods for sequentially centrifuging discrete samples provide improved operating efficiencies over conventional batch centrifuges. Such advantages include reducing dwell time, increasing system throughput, reducing sample processing system footprint, and improving precision of the analytical process. The sequential centrifuge further provides the capability of handling critical samples without compromising the operating efficiencies achieved in centrifuging discrete samples in a sequential manner.Type: GrantFiled: December 10, 2008Date of Patent: December 15, 2015Assignee: TriPath Imaging, Inc.Inventors: William Alan Fox, Charles L. Carrico
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Publication number: 20150132798Abstract: The invention provides an integrated sequential sample preparation system using a sequential centrifuge for preparing samples for analysis. Methods of more efficiently preparing discrete samples sequentially for subsequent analysis are also provided. The apparatus and methods for sequentially preparing discrete samples provide improved operating efficiencies over conventional preparation processes that use batch centrifugation systems. Such advantages include reducing dwell time, increasing system throughput, reducing sample preparation system footprint, and improving precision of the analytical process. The integrated sequential preparation system with the integrated sequential centrifuge further provides the capability of handling critical or STAT samples without compromising the operating efficiencies achieved by preparing discrete samples in a sequential manner.Type: ApplicationFiled: January 9, 2015Publication date: May 14, 2015Inventors: William Alan Fox, Charles L. Carrico, JR.
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Patent number: 8956578Abstract: The invention provides an integrated sequential sample preparation system using a sequential centrifuge for preparing samples for analysis. Methods of more efficiently preparing discrete samples sequentially for subsequent analysis are also provided. The apparatus and methods for sequentially preparing discrete samples provide improved operating efficiencies over conventional preparation processes that use batch centrifugation systems. Such advantages include reducing dwell time, increasing system throughput, reducing sample preparation system footprint, and improving precision of the analytical process. The integrated sequential preparation system with the integrated sequential centrifuge further provides the capability of handling critical or STAT samples without compromising the operating efficiencies achieved by preparing discrete samples in a sequential manner.Type: GrantFiled: March 10, 2009Date of Patent: February 17, 2015Assignee: TriPath Imaging, Inc.Inventors: William Alan Fox, Charles L. Carrico, Jr.
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Publication number: 20110104742Abstract: The invention provides an integrated sequential sample preparation system using a sequential centrifuge for preparing samples for analysis. Methods of more efficiently preparing discrete samples sequentially for subsequent analysis are also provided. The apparatus and methods for sequentially preparing discrete samples provide improved operating efficiencies over conventional preparation processes that use batch centrifugation systems. Such advantages include reducing dwell time, increasing system throughput, reducing sample preparation system footprint, and improving precision of the analytical process. The integrated sequential preparation system with the integrated sequential centrifuge further provides the capability of handling critical or STAT samples without compromising the operating efficiencies achieved by preparing discrete samples in a sequential manner.Type: ApplicationFiled: March 10, 2009Publication date: May 5, 2011Inventors: William Alan Fox, Charles L. Carrico, JR.
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Publication number: 20110003674Abstract: The invention provides a sequential centrifuge for centrifuging discrete samples. Methods of more efficiently centrifuging discrete samples sequentially are also provided. The apparatus and methods for sequentially centrifuging discrete samples provide improved operating efficiencies over conventional batch centrifuges. Such advantages include reducing dwell time, increasing system throughput, reducing sample processing system footprint, and improving precision of the analytical process. The sequential centrifuge further provides the capability of handling critical samples without compromising the operating efficiencies achieved in centrifuging discrete samples in a sequential manner.Type: ApplicationFiled: December 10, 2008Publication date: January 6, 2011Inventors: William Alan Fox, Charles L. Carrico
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Patent number: 5419279Abstract: An apparatus for use in depositing and staining cytological material on a microscope slide has an elongated hollow tube, a base member, at least one flange, and a base plate. The base member is attached to the bottom end of the tube and projects outwardly from the tube perpendicular to the longitudinal axis of the tube. At least one flange is connected to the base member and outwardly-extends from the base member perpendicular to the longitudinal axis of the tube. The base member has a recessed area configured to receive the microscope slide, and slots configured and dimensioned to receive the flange. A passage in the base plate extends from each slot to releasably secure the respective flange when the tube is rotated. As designed, this apparatus advantageously allows individual staining of a slide, thereby preventing false-positive results due to floater cells which can translocate between slides in a common bath.Type: GrantFiled: March 14, 1994Date of Patent: May 30, 1995Assignee: Hoffmann-La Roche Inc.Inventors: Charles L. Carrico, Jr., William A. Fox, Ernest A. Knesel, Jr.
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Patent number: 5356814Abstract: A device for disaggregating cytological material includes a cylindrical body and a plurality of shear plates at least one of which is located at the bottom end of the cylindrical body. The shear plates have a plurality of holes or slots formed therein which disaggregate the cellular sample and permit the passage of single cells and small cell clusters into a chamber defined by the cylindrical body.Type: GrantFiled: August 30, 1993Date of Patent: October 18, 1994Assignee: Hoffmann-La Roche Inc.Inventors: Charles L. Carrico, Jr., William A. Fox, James W. Geyer, Ernest A. Knesel, Jr.
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Patent number: 5346831Abstract: A process for producing a monolayer of cytological material on an optically-clear, cationically-charged substrate, includes the steps of separating the cytological material by centrifugation over a density gradient, producing a packed pellet of the cytological material, mixing the pellet of the cytological material, withdrawing an aliquot of a predetermined volume of the material from the mixed pellet of the cytological material, depositing the aliquot and a predetermined volume of water into a sedimentation vessel, which is removably secured to the substrate, allowing the cytological material to settle onto the substrate under the force of gravity, and after settlement of the cytological material, removing the water from the sedimentation vessel.Type: GrantFiled: August 30, 1993Date of Patent: September 13, 1994Assignee: Hoffman-La Roche Inc.Inventors: Charles L. Carrico, Jr., William A. Fox, James W. Geyer, Ernest A. Knesel, Jr.