Patents by Inventor Charles Linder

Charles Linder has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220249539
    Abstract: Bolaamphiphilic compounds are provided according to formula I: HG2-L1-HG1??I where HG1, HG2 and L1 are as defined herein. Provided bolaamphilphilic compounds and the pharmaceutical compositions thereof are useful for delivering biologically active drugs into animal or human brain.
    Type: Application
    Filed: January 28, 2022
    Publication date: August 11, 2022
    Inventors: Charles LINDER, Eliahu HELDMAN, Sarina GRINBERG
  • Patent number: 11304964
    Abstract: Bolaamphiphilic compounds are provided according to formula I: HG2-L1-HG1?? I where HG1, HG2 and L1 are as defined herein. Provided bolaamphiphilic compounds and the pharmaceutical compositions thereof are useful for delivering HIV active drugs into animal or human brain.
    Type: Grant
    Filed: July 10, 2014
    Date of Patent: April 19, 2022
    Assignee: Lauren Sciences LLC
    Inventors: Charles Linder, Sarina Grinberg, Eliahu Heldman
  • Publication number: 20220072098
    Abstract: Bolaamphiphilic compounds are provided according to formula I: HG2-L1-HG1 ??I where HG1, HG2 and L1 are as defined herein. Provided bolaamphilphilic compounds and the pharmaceutical compositions thereof are useful for delivering GDNF or NGF into animal or human brain.
    Type: Application
    Filed: June 18, 2021
    Publication date: March 10, 2022
    Inventors: Charles LINDER, Eliahu HELDMAN, Sarina GRINBERG
  • Patent number: 11246297
    Abstract: A container for a nucleus hive of bees including a box having a polygonal shaped bottom and a plurality of side walls. Each one of the plurality of side walls extends upwardly from an edge of the polygonal shaped bottom. A side edge of each side wall is attached to a side edge of an adjacent side wall and upper edges of the side walls form an opening. The opening has an area larger than the area of the polygonal shaped bottom and a shape substantially corresponding to the polygonal shaped bottom. A hive frame support means is positioned on inner wall surfaces of a plurality of the side walls. A polygonal shaped removable lid is configured to rest upon and cover the opening. The box and lid are preferably formed from a rigid commodity grade plastic material.
    Type: Grant
    Filed: December 27, 2019
    Date of Patent: February 15, 2022
    Inventor: Charles Linder
  • Patent number: 11189363
    Abstract: A method of characterizing chemical and/or morphological features of a material, comprising acquiring energy relaxation data from 1H low field nuclear magnetic resonance (1H LF-NMR) measurements of said material, converting the relaxation signals into a multidimensional distribution of longitudinal and transverse relaxation times by solving an inverse problem under both L1 and L2 regularizations and further imposing a non-negativity constraint, and identifying one or more characteristics of said material with the aid of said multidimensional T1-T2 distribution. The method is useful, inter alia, in monitoring chemical processes, screening of additives and quality control.
    Type: Grant
    Filed: September 6, 2019
    Date of Patent: November 30, 2021
    Inventors: Ze'ev Wiesman, Charles Linder, Ofer Levi
  • Publication number: 20210106687
    Abstract: Bolaamphiphilic compounds are provided according to formula I: where HG1, HG2 and L1 are as defined herein. Provided bolaamphilphilic compounds and the pharmaceutical compositions thereof are useful for delivering imaging agents into animal or human brain.
    Type: Application
    Filed: December 22, 2020
    Publication date: April 15, 2021
    Inventors: Charles LINDER, Eliahu HELDMAN, Sarina GRINBERG
  • Publication number: 20210023009
    Abstract: Nano-sized particles are provided comprising at least one multi-headed amphiphilic compound, in which at least one headgroup of said multi-headed amphiphilic compound is selectively cleavable or contains a selectively cleavable group, and at least one biologically active agent, which is both encapsulated within the nano-particle and non-covalently associated thereto.
    Type: Application
    Filed: October 15, 2020
    Publication date: January 28, 2021
    Inventors: Charles LINDER, Sarina GRINBERG, Eliahu HELDMAN
  • Patent number: 10842747
    Abstract: Nano-sized particles are provided comprising at least one multi-headed amphiphilic compound, in which at least one headgroup of said multi-headed amphiphilic compound is selectively cleavable or contains a selectively cleavable group, and at least one biologically active agent, which is both encapsulated within the nano-particle and non-covalently associated thereto.
    Type: Grant
    Filed: May 9, 2017
    Date of Patent: November 24, 2020
    Assignee: Ben-Gurion University of Negev R & D
    Inventors: Charles Linder, Sarina Grinberg, Eliahu Heldman
  • Publication number: 20200241095
    Abstract: A method of characterizing chemical and/or morphological features of a material, comprising acquiring energy relaxation data from 1H low field nuclear magnetic resonance (1H LF-NMR) measurements of said material, converting the relaxation signals into a multidimensional distribution of longitudinal and transverse relaxation times by solving an inverse problem under both L1 and L2 regularizations and further imposing a non-negativity constraint, and identifying one or more characteristics of said material with the aid of said multidimensional T1-T2 distribution. The method is useful, inter alia, in monitoring chemical processes, screening of additives and quality control.
    Type: Application
    Filed: September 6, 2019
    Publication date: July 30, 2020
    Inventors: Ze'ev WIESMAN, Charles LINDER, Ofer LEVI
  • Publication number: 20200205383
    Abstract: A container for a nucleus hive of bees is provided including a box having a polygonal shaped bottom and a plurality of side walls. Each one of the plurality of side walls extends upwardly from an edge of the polygonal shaped bottom. A side edge of each side wall is attached to a side edge of an adjacent side wall and upper edges of the side walls form an opening. The opening has an area larger than the area of the polygonal shaped bottom and a shape substantially corresponding to the polygonal shaped bottom. A hive frame support means is positioned on inner wall surfaces of a plurality of the side walls. A polygonal shaped removable lid is configured to rest upon and cover the opening. The box and lid are preferably formed from a rigid commodity grade plastic material.
    Type: Application
    Filed: December 27, 2019
    Publication date: July 2, 2020
    Inventor: Charles Linder
  • Publication number: 20190381137
    Abstract: Bolaamphiphilic compounds are provided according to formula I: HG2-L1-HG1?? I where HG1, HG2 and L1 are as defined herein. Provided bolaamphilphilic compounds and the pharmaceutical compositions thereof are useful for delivering siRNA into animal or human cell.
    Type: Application
    Filed: June 27, 2019
    Publication date: December 19, 2019
    Inventors: Charles LINDER, Eliahu HELDMAN, Sarina GRINBERG
  • Publication number: 20190216895
    Abstract: Bolaamphiphilic compounds are provided according to formula I: HG2—L1—HG1 ??I where HG1, HG2 and L1 are as defined herein. Provided bolaamphilphilic compounds and the pharmaceutical compositions thereof are useful for delivering GDNF or NGF into animal or human brain.
    Type: Application
    Filed: November 12, 2018
    Publication date: July 18, 2019
    Inventors: Charles LINDER, Eliahu HELDMAN, Sarina GRINBERG
  • Publication number: 20190076533
    Abstract: Bolaamphiphilic compounds are provided according to formula I: HG2-L1-HG1??I where HG1, HG2 and L1 are as defined herein. Provided bolaamphilphilic compounds and the pharmaceutical compositions thereof are useful for delivering imaging agents into animal or human brain.
    Type: Application
    Filed: July 25, 2018
    Publication date: March 14, 2019
    Inventors: Charles LINDER, Eliahu Heldman, Sarina Grinberg
  • Publication number: 20180220627
    Abstract: A package and system for holding and transporting small living beings, particularly, insects such as honeybees and the like, configurable in a robust, sturdy three-dimensional shape for handling and transport by mail and commercial carriers, which prevents stinging from within the package, allows escape of smaller accompanying insects such as hive beetles, is interlocking with others of the packages and strong enough to support other packages and items thereon; that provides for air flow through and about the package for heat dissipation for proper honeybee environment; that accommodates food and separately carrying a queen bee; and that can be easily and quickly broken down into a non-operational, generally flat configuration for initial sale, transport, and storage.
    Type: Application
    Filed: April 2, 2018
    Publication date: August 9, 2018
    Inventors: Charles Linder, Bryan S. Claerhout
  • Patent number: 9930869
    Abstract: A package and system for holding and transporting small living beings, particularly, insects such as honeybees and the like, configurable in a robust, sturdy three-dimensional shape for handling and transport by mail and commercial carriers, which prevents stinging from within the package, allows escape of smaller accompanying insects such as hive beetles, is interlocking with others of the packages and strong enough to support other packages and items thereon; that provides for air flow through and about the package for heat dissipation for proper honeybee environment; that accommodates food and separately carrying a queen bee; and that can be easily and quickly broken down into a non-operational, generally flat configuration for initial sale, transport, and storage.
    Type: Grant
    Filed: November 19, 2014
    Date of Patent: April 3, 2018
    Inventors: Charles Linder, Bryan S. Claerhout
  • Publication number: 20180036376
    Abstract: Bolaamphiphilic compounds are provided according to formula I: HG2-L1-HG1??I where HG1, HG2 and L1 are as defined herein. Provided bolaamphilphilic compounds and the pharmaceutical compositions thereof are useful for delivering siRNA into animal or human cell.
    Type: Application
    Filed: July 20, 2017
    Publication date: February 8, 2018
    Inventors: Charles LINDER, Eliahu HELDMAN, Sarina GRINBERG
  • Publication number: 20180021368
    Abstract: Bolaamphiphilic compounds are provided according to formula I: HG2-L1-HG1?? I where HG1, HG2 and L1 are as defined herein. Provided bolaamphilphilic compounds and the pharmaceutical compositions thereof are useful for delivering biologically active drugs into animal or human brain.
    Type: Application
    Filed: June 30, 2017
    Publication date: January 25, 2018
    Inventors: Charles LINDER, Eliahu HELDMAN, Sarina GRINBERG
  • Publication number: 20170367980
    Abstract: Nano-sized particles are provided comprising at least one multi-headed amphiphilic compound, in which at least one headgroup of said multi-headed amphiphilic compound is selectively cleavable or contains a selectively cleavable group, and at least one biologically active agent, which is both encapsulated within the nano-particle and non-covalently associated thereto.
    Type: Application
    Filed: May 9, 2017
    Publication date: December 28, 2017
    Inventors: Charles LINDER, Sarina GRINBERG, Eliahu HELDMAN
  • Patent number: 9717240
    Abstract: Method for the preparation of microencapsulated essential oils or a formulation thereof for various non-agricultural applications.
    Type: Grant
    Filed: November 5, 2015
    Date of Patent: August 1, 2017
    Assignee: BOTANOCAP LTD.
    Inventors: Arie Markus, Pnina Strongin, Charles Linder
  • Publication number: 20170189864
    Abstract: The present invention discloses stable composite membranes comprising a porous support having one or more thin selective layers coated on a top surface thereof, whereas at least one of said thin selective layers comprises a crosslinked fluorinated silicone polymer, and further wherein the total thickness of said one or more thin selective layers ranges between 0.1 to 10 microns. The use of these membranes in the process of olive oil wastewater treatment and the valorization of polyphenol-rich by-products, are also disclosed.
    Type: Application
    Filed: May 27, 2015
    Publication date: July 6, 2017
    Applicant: B.G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD., AT BEN-GURION UNIVERSITY
    Inventors: Jack GILRON, Charles LINDER, Zeev WIESMAN