Patents by Inventor Charles M. Baum

Charles M. Baum has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF TREATING OVARIAN CANCER
    Publication number: 20100112039
    Abstract: Disclosed are methods of treating ovarian cancer (e.g., epithelial ovarian cancer) using lonafarnib, a taxane (e.g., paclitaxel or docetaxel) and a platinum coordinator complex (e.g., carboplatin, cisplatin or oxaliplatin). Also disclosed are methods of treating ovarian cancer (e.g. epithelial ovarian cancer) using lonafarnib, paclitaxel and carboplatin. Also disclosed are methods of treating ovarian cancer using lonafarnib in combination with a liposomal doxorubicin.
    Type: Application
    Filed: October 23, 2007
    Publication date: May 6, 2010
    Applicant: SCHERING CORPORATION
    Inventors: Thomas M. Estok, Sara Zaknoen, Charles M. Baum
  • Combinations and Methods of Using an Indolinone Compound
    Publication number: 20080193448
    Abstract: The invention provides methods of treating cancer using a compound of formula (1) or a pharmaceutically acceptable salt thereof, particularly a malate salt, in combination with various additional therapeutic agents. The invention also provides therapeutic dosing regimens, using the compound of formula (1) and an additional therapeutic agent.
    Type: Application
    Filed: May 4, 2006
    Publication date: August 14, 2008
    Applicant: PFIZER INC.
    Inventor: Charles M. Baum
  • Multi-functional hematopoietic fusion proteins between sequence rearranged G-CSF receptor agonists and other hematopoietic factors
    Publication number: 20040171115
    Abstract: Disclosed are novel multi-functional hematopoietic receptor agonist proteins, DNAs which encode the multi-functional hematopoietic receptor agonists proteins, methods of making the multi-functional hematopoietic receptor agonists proteins and methods of using the multi-functional hematopoietic receptor agonists proteins.
    Type: Application
    Filed: October 27, 2003
    Publication date: September 2, 2004
    Inventors: Yiqing Feng, Nicholas R. Staten, Charles M. Baum, Neena L. Summers, Maire Helena Caparon, S. Christopher Bauer, Linda L. Zurfluh, John P. McKearn, Barbara K. Klein, Stephen C. Lee, Charles A. McWherter, Judith G. Giri
  • Fused G-CSF and IL-3 proteins and uses thereof
    Patent number: 6730303
    Abstract: Disclosed are novel multi-functional hematopoietic receptor agonist proteins, DNAs which encode the multi-functional hematopoietic receptor agonists proteins, methods of making the multi-functional hematopoietic receptor agonists proteins and methods of using the multi-functional hematopoietic receptor agonists proteins.
    Type: Grant
    Filed: February 22, 2000
    Date of Patent: May 4, 2004
    Assignee: Pharmacia Corporation
    Inventors: Yiqing Feng, Nicholas R. Staten, Charles M. Baum, Neena L. Summers, Maire Helena Caparon, S. Christopher Bauer, Linda L. Zurfluh, John P. McKearn, Barbara K. Klein, Stephen C. Lee, Charles A. McWherter, Judith G. Giri
  • Thrombopoietin: IL-3 fusion protein
    Patent number: 6254870
    Abstract: The present invention relates to variants of human c-mpl ligands (thrombopoietin) with activity on hematopoietic differentiation and expansion.
    Type: Grant
    Filed: January 30, 1998
    Date of Patent: July 3, 2001
    Assignee: G. D. Searle & Co.
    Inventors: Nicholas R. Staten, Jean P. Favara, Larry E. Kahn, Lyle E. Pegg, John P. McKearn, Charles M. Baum
  • Multi-functional hematopoietic fusion proteins between sequence rearranged C-MPL receptor agonists and other hematopoietic factors
    Patent number: 6066318
    Abstract: Disclosed are novel multi-functional hematopoietic receptor agonist proteins, DNAs which encode the multi-functional hematopoietic receptor agonists proteins, methods of making the multi-functional hematopoietic receptor agonists proteins and methods of using the multi-functional hematopoietic receptor agonists proteins.
    Type: Grant
    Filed: April 4, 1997
    Date of Patent: May 23, 2000
    Assignee: G.D. Searle & Co.
    Inventors: Yiqing Feng, Nicholas R. Staten, Charles M. Baum, Neena L. Summers, Maire Helena Caparon, S. Christopher Bauer, Linda L. Zurfluh, John P. McKearn, Barbara K. Klein, Stephen C. Lee, Charles A. McWherter, Judith G. Giri
  • Human hematopoietic stem cell
    Patent number: 5914108
    Abstract: Human hematopoietic stem cells are provided by separation of the stem cells from dedicated cells. The stem cells may than be maintained by regeneration in an appropriate growth medium. Means are provided for assaying for the stem cells as to their capability for producing members of each of the hematopoietic lineages. A method for treating a human by implanting a cellular composition comprising greater than 90% human hematopoietic stem cells is also disclosed.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: June 22, 1999
    Assignee: Systemix, Inc.
    Inventors: Ann Tsukamoto, Charles M. Baum, Yukoh Aihara, Irving Weissman
  • Human hematopoietic stem cell
    Patent number: 5763197
    Abstract: Human hematopoietic stem cells are provided by separation of the stem cells from dedicated cells. The stem cells may than be maintained by regeneration in an appropriate growth medium. Means are provided for assaying for the stem cells as to their capability for producing members of each of the hematopoietic lineages.
    Type: Grant
    Filed: June 25, 1991
    Date of Patent: June 9, 1998
    Assignee: Systemix, Inc.
    Inventors: Ann Tsukamoto, Charles M. Baum, Yukoh Aihara, Irving Weissman
  • Human hematopoietic stem cell
    Patent number: 5750397
    Abstract: Human hematopoietic stem cells are provided by separation of the stem cells from dedicated cells. The stem cells may than be maintained by regeneration in an appropriate growth medium. Means are provided for assaying for the stem cells as to their capability for producing members of each of the hematopoietic lineages.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: May 12, 1998
    Assignee: Systemix, Inc.
    Inventors: Ann Tsukamoto, Charles M. Baum, Yukoh Aihara, Irving Weissman
  • Human hematopoietic stem cell
    Patent number: 5716827
    Abstract: Human hematopoietic stem cells are provided by separation of the stem cells from dedicated cells. The stem cells may than be maintained by regeneration in an appropriate growth medium. Means are provided for assaying for the stem cells as to their capability for producing members of each of the hematopoietic lineages.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: February 10, 1998
    Assignee: SyStemix, Inc.
    Inventors: Ann Tsukamoto, Charles M. Baum, Yukoh Aihara, Irving Weissman
  • Identification and isolation of human hematopoietic stem cells
    Patent number: 5643741
    Abstract: Human hematopoietic stem cells are identified according to expression of specific cell surface markers. Substantially homogenous stem cell compositions are obtained by selective isolation of cells free of markers associated with differentiated cells, while displaying epitopic characteristics associated with the stem cells. The stem cells may then be maintained by regeneration in an appropriate growth medium. Means are provided for assaying for the stem cells as to their capability for producing members of each of the hematopoietic lineages.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: July 1, 1997
    Assignee: Systemix, Inc.
    Inventors: Ann Tsukamoto, Charles M. Baum, Yukoh Aihara, Irving Weissman
  • Human hematopoietic stem cell
    Patent number: 5061620
    Abstract: Human hematopoietic stem cells are provided by separation of the stem cells from dedicated cells. The stem cells may than be maintained by regeneration in an appropriate growth medium. Means are provided for assaying for the stem cells as to their capability for producing members of each of the hematopoietic lineages.
    Type: Grant
    Filed: March 30, 1990
    Date of Patent: October 29, 1991
    Assignee: SyStemix, Inc.
    Inventors: Ann Tsukamoto, Charles M. Baum, Yukoh Aihara, Irving Weissman