Patents by Inventor Charles M. Moehle

Charles M. Moehle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CANDIDA ALBICANS mRNA 5'5-TRIPHOSPHATASE (CET-1) POLYNUCLEOTIDES
    Publication number: 20020018774
    Abstract: The present invention relates to enzymes involved in capping of fungal mRNAs, and molecules that inhibit such enzymes. In particular, the invention relates to the novel C. albicans capping enzyme genes ABD1 and CET1 and their encoded protein products, as well as derivatives and analogs thereof. The invention also relates to methods of using of fungal capping enzymes to screen for fungal inhibitors.
    Type: Application
    Filed: December 17, 1998
    Publication date: February 14, 2002
    Inventors: SIMON GREEN, GARY DALLMANN, MAGDELEINE HUNG, JULIE LANE, CHARLES M. MOEHLE
  • Methods for screening for antibiotics
    Patent number: 5998159
    Abstract: The present invention provides methods for identification of antibiotic agents which cause the accumulation of ppGpp in bacterial organisms involving a relA-independent pathway. The methods comprise screening assays in which test compounds are brought into contact with relA.sup.- test cells and observing the effect such compounds have on ppGpp levels in the test cells. The invention also provides genetically manipulated relA.sup.- test cells which contain a reporter gene the expression of which is sensitive to the level of ppGpp. The invention also encompasses agents identified by the screening assays, and uses of these agents in the treatment of infectious diseases.
    Type: Grant
    Filed: February 10, 1998
    Date of Patent: December 7, 1999
    Assignee: RiboGene, Inc.
    Inventors: Julia C. Watson, Charles M. Moehle, Ritu Gina Bahador, Victor James Hernandez
  • Methods for screening for antimycotics
    Patent number: 5871923
    Abstract: Screening methods for identification of antimy-cotic agents active in mycotic cell translation, the agents identified thereby, and uses of these agents.
    Type: Grant
    Filed: February 19, 1997
    Date of Patent: February 16, 1999
    Assignee: Ribogene, Inc.
    Inventor: Charles M. Moehle
  • Methods for screening for antimycotics
    Patent number: 5641627
    Abstract: This application relates to screening methods for identification of antimycotic agents active in mycotic cell translation, the agents identified thereby, and uses of these agents.
    Type: Grant
    Filed: October 24, 1994
    Date of Patent: June 24, 1997
    Assignee: RiboGene, Inc.
    Inventor: Charles M. Moehle