Patents by Inventor Charles M. Zepp

Charles M. Zepp has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immune system modulators
    Patent number: 10117875
    Abstract: The present invention relates to a compound of Formula I: or a pharmaceutically acceptable salt thereof, wherein the symbols are as defined in the specification; a pharmaceutical composition comprising the same; and a method for treating or preventing autoimmunity disease using the same.
    Type: Grant
    Filed: April 3, 2017
    Date of Patent: November 6, 2018
    Assignee: JANUS BIOTHERAPEUTICS, INC.
    Inventors: Grayson B. Lipford, Charles M. Zepp
  • Imidazole quinoline-based immune system modulators
    Patent number: 9873694
    Abstract: The present invention relates to a compound of Formula I: or an enantiomer, diastereomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein the symbols are as defined in the specification; a pharmaceutical composition comprising the same; and a method for treating or preventing autoimmunity disease using the same.
    Type: Grant
    Filed: October 3, 2012
    Date of Patent: January 23, 2018
    Assignee: JANUS BIOTHERAPEUTICS, INC.
    Inventors: Grayson B. Lipford, Charles M. Zepp
  • NOVEL N2, N4, N7, 6-TETRASUBSTITUTED PTERIDINE-2,4,7-TRIAMINE AND 2, 4, 6, 7-TETRASUBSTITUTED PTERIDINE COMPOUNDS AND METHODS OF SYNTHESIS AND USE THEREOF
    Publication number: 20170275287
    Abstract: Compounds as immune system modulators bearing a pteridine core are described. A pharmaceutical composition comprising the same, methods of making the same, and a method for treating or preventing autoimmunity disease using the same are described.
    Type: Application
    Filed: August 21, 2015
    Publication date: September 28, 2017
    Applicant: Janus Biotherapeutics, Inc.
    Inventors: Grayson B. LIPFORD, Charles M. ZEPP
  • NOVEL IMMUNE SYSTEM MODULATORS
    Publication number: 20170224699
    Abstract: The present invention relates to a compound of Formula I: or a pharmaceutically acceptable salt thereof, wherein the symbols are as defined in the specification; a pharmaceutical composition comprising the same; and a method for treating or preventing autoimmunity disease using the same.
    Type: Application
    Filed: April 3, 2017
    Publication date: August 10, 2017
    Inventors: Grayson B. LIPFORD, Charles M. ZEPP
  • Immune system modulators
    Patent number: 9637489
    Abstract: The present invention relates to a compound of Formula I: or a pharmaceutically acceptable salt thereof, wherein the symbols are as defined in the specification; a pharmaceutical composition comprising the same; and a method for treating or preventing autoimmunity disease using the same.
    Type: Grant
    Filed: September 4, 2015
    Date of Patent: May 2, 2017
    Assignee: JANUS BIOTHERAPEUTICS, INC.
    Inventors: Grayson B. Lipford, Charles M. Zepp
  • Immune system modulators
    Patent number: 9359361
    Abstract: The present invention relates to a compound of Formula I: or a pharmaceutically acceptable salt thereof, wherein the symbols are as defined in the specification; a pharmaceutical composition comprising the same; and a method for treating or preventing autoimmunity disease using the same.
    Type: Grant
    Filed: June 1, 2012
    Date of Patent: June 7, 2016
    Assignee: JANUS BIOTHERAPEUTICS, INC.
    Inventors: Grayson B. Lipford, Charles M. Zepp
  • Immune system modulators
    Patent number: 9353115
    Abstract: The present invention relates to a compound of Formula I: or a pharmaceutically acceptable salt thereof, wherein the symbols are as defined in the specification; a pharmaceutical composition comprising the same; and a method for treating or preventing autoimmunity disease using the same.
    Type: Grant
    Filed: June 1, 2012
    Date of Patent: May 31, 2016
    Assignee: JANUS BIOTHERAPEUTICS, INC.
    Inventors: Grayson B. Lipford, Charles M. Zepp
  • NOVEL IMMUNE SYSTEM MODULATORS
    Publication number: 20160074403
    Abstract: The present invention relates to a compound of Formula I: or a pharmaceutically acceptable salt thereof, wherein the symbols are as defined in the specification; a pharmaceutical composition comprising the same; and a method for treating or preventing autoimmunity disease using the same.
    Type: Application
    Filed: September 4, 2015
    Publication date: March 17, 2016
    Inventors: Grayson B. LIPFORD, Charles M. ZEPP
  • Immune system modulators
    Patent number: 9126996
    Abstract: The present invention relates to a compound of Formula I: or a pharmaceutically acceptable salt thereof, wherein the symbols are as defined in the specification; a pharmaceutical composition comprising the same; and a method for treating or preventing autoimmunity disease using the same.
    Type: Grant
    Filed: February 12, 2014
    Date of Patent: September 8, 2015
    Assignee: JANUS BIOTHERAPEUTICS, INC.
    Inventors: Grayson B. Lipford, Charles M. Zepp
  • NOVEL IMIDAZOLE QUINOLINE-BASED IMMUNE SYSTEM MODULATORS
    Publication number: 20140242121
    Abstract: The present invention relates to a compound of Formula I: or an enantiomer, diastereomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein the symbols are as defined in the specification; a pharmaceutical composition comprising the same; and a method for treating or preventing autoimmunity disease using the same.
    Type: Application
    Filed: October 3, 2012
    Publication date: August 28, 2014
    Applicant: JANUS BIOTHERAPEUTICS, INC.
    Inventors: Grayson B. Lipford, Charles M. Zepp
  • NOVEL IMMUNE SYSTEM MODULATORS
    Publication number: 20140221646
    Abstract: The present invention relates to a compound of Formula I: or a pharmaceutically acceptable salt thereof, wherein the symbols are as defined in the specification; a pharmaceutical composition comprising the same; and a method for treating or preventing autoimmunity disease using the same.
    Type: Application
    Filed: February 12, 2014
    Publication date: August 7, 2014
    Applicant: JANUS BIOTHERAPEUTICS, INC.
    Inventors: Grayson B. LIPFORD, Charles M. ZEPP
  • NOVEL IMMUNE SYSTEM MODULATORS
    Publication number: 20140107115
    Abstract: The present invention relates to a compound of Formula I: or a pharmaceutically acceptable salt thereof, wherein the symbols are as defined in the specification; a pharmaceutical composition comprising the same; and a method for treating or preventing autoimmunity disease using the same.
    Type: Application
    Filed: June 1, 2012
    Publication date: April 17, 2014
    Applicant: Janus Biotherapeutics, Inc.
    Inventors: Grayson B. Lipford, Charles M. Zepp
  • NOVEL IMMUNE SYSTEM MODULATORS
    Publication number: 20140079724
    Abstract: The present invention relates to a compound of Formula I: or a pharmaceutically acceptable salt thereof, wherein the symbols are as defined in the specification; a pharmaceutical composition comprising the same; and a method for treating or preventing autoimmunity disease using the same.
    Type: Application
    Filed: June 1, 2012
    Publication date: March 20, 2014
    Applicant: Janus Biotherapeutics, Inc.
    Inventors: Grayson B. Lipford, Charles M. Zepp
  • Small Molecule Inhibitors of Toll-Like Receptor 9
    Publication number: 20100160314
    Abstract: Small molecule compounds and compositions containing said compounds useful for inhibiting signaling by certain Toll-like receptors (TLRs), particularly TLR9, are provided. The compounds and compositions can be used to inhibit immune responses, including unwanted immune responses in particular. Compounds, compositions, and methods are provided to treat a variety of conditions involving unwanted immune responses, including for example autoimmune disease, inflammation, transplant rejection, and sepsis.
    Type: Application
    Filed: September 5, 2007
    Publication date: June 24, 2010
    Inventors: Grayson B. Lipford, Charles M. Zepp, Toan B. Nguyen
  • Fatty Acid Modified Forms of Glucocorticoids
    Publication number: 20080221072
    Abstract: Compounds are disclosed of the formula in which R3 is C8 to C24 hydrocarbon or the residue of misoprostol. The compounds are useful for treating rhinitis and asthma, particularly by inhalation, and for treating inflammation, particularly by local or topical administration.
    Type: Application
    Filed: May 15, 2008
    Publication date: September 11, 2008
    Applicant: SEPRACOR INC.
    Inventors: Mark G. Currie, Steven Jones, Charles M. Zepp
  • Fatty acid modified forms of glucocorticoids
    Patent number: 7390796
    Abstract: Compounds are disclosed of the formula in which R3 is C8 to C24 hydrocarbon or the residue of misoprostol. The compounds are useful for treating rhinitis and asthma, particularly by inhalation, and for treating inflammation, particularly by local or topical administration.
    Type: Grant
    Filed: November 14, 2006
    Date of Patent: June 24, 2008
    Assignee: Sepracor Inc.
    Inventors: Mark G. Currie, Steven Jones, Charles M. Zepp
  • Marking and authenticating articles
    Patent number: 7220535
    Abstract: Disclosed herein are methods and apparatus for providing markings upon objects, including the read side of an optical information media, where the markings do not substantially interfere with object, including the use of the optical information media. This invention discloses use of a coating, marking schemes, printing of markings with UV light, as well as methods and apparatus for reading and deciphering said marking. Included is an authentication scheme, where the marking may be used as a lock to limit access to information contained in an optical information media.
    Type: Grant
    Filed: June 6, 2002
    Date of Patent: May 22, 2007
    Assignee: Spectra Systems Corporation
    Inventors: Nabil M. Lawandy, Jeffrey L. Conroy, Robert S. Afzal, Allison Berube, Charles M. Zepp, Andrei Smuk
  • Thermochromic compositions of color formers and lewis acids
    Patent number: 6908505
    Abstract: Thermochromic compositions that include combinations of at least one color former and at least one Lewis acid in a polymer mixture are disclosed. The thermochromic compositions reversibly change appearance from substantially transparent to substantially non-transparent above a lower critical solution temperature.
    Type: Grant
    Filed: October 1, 2003
    Date of Patent: June 21, 2005
    Assignee: Spectra Systems Corporation
    Inventors: Nabil M. Lawandy, Timothy J. Driscoll, Charles M. Zepp
  • Contrast enhancing marking system for application of unobtrusive identification and other markings
    Patent number: 6881915
    Abstract: A method and a system is disclosed for affixing invisible or unobtrusive markings to mail pieces (4), and subsequently collecting information from the mail pieces for sorting purposes. The system includes the affixation of an optically contrasting layer (1) to a mail piece, the layer changing optically upon the application of a stimulus to present a contrasting background for imaging encoded information (3) applied over the layer and related to the mail piece.
    Type: Grant
    Filed: January 30, 2002
    Date of Patent: April 19, 2005
    Assignee: Spectra Systems Corporation
    Inventors: Nabil M. Lawandy, Timothy J. Driscoll, Charles M. Zepp
  • Fatty acid modified forms of glucocorticoids
    Publication number: 20040235811
    Abstract: Compounds are disclosed of the formula 1
    Type: Application
    Filed: October 8, 2003
    Publication date: November 25, 2004
    Applicant: Sepracor Inc.
    Inventors: Mark G. Currie, Steven Jones, Charles M. Zepp