Patents by Inventor Charles Magness

Charles Magness has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Detection of mutations in a gene associated with resistance to viral infection, OAS1
    Publication number: 20070154467
    Abstract: A method for detecting a mutation related to the gene encoding OAS1. This and other disclosed mutations correlate with resistance of humans to viral infection including hepatitis C. Also provided is a therapeutic agent consisting of a protein or polypeptide encoded by the mutated gene, or a polynucleotide encoding the protein or polypeptide. Inhibitors of human OAS1, including antisense oligonucleotides, methods, and compositions specific for human OAS1, are also provided.
    Type: Application
    Filed: November 2, 2006
    Publication date: July 5, 2007
    Applicant: Illumigen Biosciences, Inc.
    Inventors: Shawn Iadonato, Charles Magness, Gary Rosenberg, Christina Scherer, Thierry Guillaudeux
  • Detection of mutations in a gene associated with resistance to viral infection, OAS2 and OAS3
    Publication number: 20070111231
    Abstract: Compositions and methods are provided for detecting a mutation in a human oligoadenylate synthetase gene, particularly OAS2 or OAS3, wherein the mutation confers resistance to flavivirus infection, including infection by hepatitis C virus, and the mutation relates to other disease states including prostate cancer and diabetes, and uses of the encoded proteins and antibodies thereto.
    Type: Application
    Filed: August 23, 2006
    Publication date: May 17, 2007
    Applicant: Illumigen Biosciences, Inc.
    Inventors: Charles Magness, Shawn Iadonato, Christina Scherer, Phillip Fellin, Kathryn Steiger
  • Mutations in OAS1 genes
    Publication number: 20060275802
    Abstract: Modified amino acid sequences of OAS1 proteins in non-human primates, and genes related thereto, are provided.
    Type: Application
    Filed: May 3, 2006
    Publication date: December 7, 2006
    Inventors: Shawn Iadonato, Charles Magness, P. Fellin, Christina Scherer, Tory Hagen, Amy Olson
  • Method and apparatus for pattern identification in diploid DNA sequence data
    Publication number: 20060154290
    Abstract: This invention provides methods for identifying mutations and methylation patterns in diploid DNA sequence signal data. In particular, the invention provides methods for (1) obtaining two parental allele sequences from diploid DNA sequence signal data, (2) identifying the mutation and haplotype patterns in the two parental allele sequences, (3) assigning likelihood scores for the mutations thus identified, and (4) identifying patterns of methylation.
    Type: Application
    Filed: February 3, 2006
    Publication date: July 13, 2006
    Applicant: Illumigen Biosciences, Inc.
    Inventors: Charles Magness, Dake Sun
  • Detection of mutations in a gene associated with resistance to viral infection, OAS1
    Publication number: 20050191649
    Abstract: A method for detecting a mutation related to the gene encoding OAS1. This and other disclosed mutations correlate with resistance of humans to viral infection including hepatitis C. Also provided is a therapeutic agent consisting of a protein or polypeptide encoded by the mutated gene, or a polynucleotide encoding the protein or polypeptide. Inhibitors of human OAS1, including antisense oligonucleotides, methods, and compositions specific for human OAS1, are also provided.
    Type: Application
    Filed: October 22, 2004
    Publication date: September 1, 2005
    Applicant: Illumigen Biosciences, Inc.
    Inventors: Shawn Iadonato, Charles Magness, Gary Rosenberg, Christina Scherer