Abstract: Fluid transfer assemblies for transferring fluid into or out of a single vessel and distributing the fluid to multiple other vessels are provided. The fluid transfer assemblies are customizable, substantially aseptic, and single-use. The fluid transfer assemblies may be manufactured by solidifying polymeric materials to form a body around a mandrel with protrusions engaged to fluid conduits and leaving recesses in the solidified polymeric material to stretch the resultant body and remove the mandrel with protrusions. The resultant fluid transfer assembly may be surrounded by a rigid housing and valves may be engaged with the conduits and/or body to control the fluid flow within the fluid transfer assembly.

Abstract: Fluid transfer assemblies for transferring fluid into or out of a single vessel and distributing the fluid to multiple other vessels are provided. The fluid transfer assemblies are customizable, substantially aseptic, and single-use. The fluid transfer assemblies may be manufactured by solidifying polymeric materials to form a body around a mandrel with protrusions engaged to fluid conduits and leaving recesses in the solidified polymeric material to stretch the resultant body and remove the mandrel with protrusions. The resultant fluid transfer assembly may be surrounded by a rigid housing and valves may be engaged with the conduits and/or body to control the fluid flow within the fluid transfer assembly.

Abstract: A system and method for transferring chemical, pharmaceutical, and/or biological material into or out of a container are provided. Further, a use of a transfer interface for accessing the interior of a disposable container is provided. The system comprises a disposable container having at least one port for accessing the interior of the container. The system further comprises a transfer interface connectable to the at least one port. The transfer interface comprises a plurality of extendable transfer elements for collecting samples from the disposable container in a sterile manner. The transfer elements may also be referred to as sampling elements, extractors, or probes. Each of the transfer elements has a corresponding biasing element for retracting the transfer element. The biasing element may be implemented as a spring or as another device capable of applying a biasing force.

Abstract: Fluid transfer assemblies for transferring fluid into or out of a single vessel and distributing the fluid to multiple other vessels are provided. The fluid transfer assemblies are customizable, substantially aseptic, and single-use. The fluid transfer assemblies may be manufactured by solidifying polymeric materials to form a body around a mandrel with protrusions engaged to fluid conduits and leaving recesses in the solidified polymeric material to stretch the resultant body and remove the mandrel with protrusions. The resultant fluid transfer assembly may be surrounded by a rigid housing and valves may be engaged with the conduits and/or body to control the fluid flow within the fluid transfer assembly.

Abstract: A flexible container is used in conjunction with a magnetic mixer. The flexible container is in the form of a bag, and is designed to rest on top of a magnetic mixer. The bag is comprised of a flexible, but impermeable-film material. The bag is flat with no seams on the bottom. A stir bar is encapsulated in a nonabrasive and soft material, such as silicone. The non-abrasive material around the stir bar permits the stir bar to directly touch the flexible film material, and prevents scratching or deteriorating of the film, as the stir bar rotates on the bottom of the flexible container.

Abstract: A flexible container is used in conjunction with a magnetic mixer. The flexible container is in the form of a bag, and is designed to rest on top of a magnetic mixer. The bag is comprised of a flexible, but impermeable-film material. A stand may be used in conjunction with bag to support larger volume flexible containers when filled with solution, permitting the exterior body of the flexible container to rest against the sides of the stand. A baffle may be interposed between the stand and bag. The baffle contacts, and thereby deforms (indents) the flexible film membrane of the container, when the container is filled with solution. So, when a stir bar of the mixer spins and fluid circulates, the baffle causes fluid to circulate erratically around a protrusion caused by the baffle, and imparts turbulence when fluid mixes around it. This prevents backflow from occurring.