Abstract: An synthetic fiber oral flavored product includes a fibrous substrate. The fibrous substrate is made of a synthetic polyester in a typically pelletized shape imbued a carrier liquid of propylene glycol or equivalent. The carrier liquid carries a freebase synthetic nicotine, a binding agent, a textural adjustment agent and flavorants. In some examples, the fibrous substrate is heat treated and modified by heating and rapid cooling the substrate to increase the zeta potential of the fibrous substrate.

Abstract: Haptens, ligands (including antibodies), immunoassays, and test kits for detecting tobacco-specific nitrosamines (TSNAs) in samples such as tobacco products are provided. The hapten is a molecule that contains one or more structural characteristics of one or more TSNAs, and is bound to an immunogenic carrier. An antibody specific for one or more TSNAs is produced by immunizing an animal with the hapten bound to the carrier. Immunoassays and test kits using those antibodies are also provided.