Abstract: An ultrasonic imaging system acquires echo signals from an object being imaged such as a moving coronary artery and the cross-correlation between echo signals is employed as an objective measure of relative object location. The method is used in a prescan procedure to determine an optimal gating window to acquire image data during a cardiac gated scan, and it is used during the scan as a real time gating signal.

Abstract: An integrated cantilever sensor array system that accurately detects and measures the presence of target substances in various environmental conditions. The integrated cantilever sensor array system comprises a cantilever sensor measurement head, a cantilever sensor system for measuring the oscillatory properties of the cantilevers and a measurement chamber. The measurement head includes a cantilever array having at least one cantilever, a light source and a detector positioned to detect incoming light reflected by the cantilevers within the cantilever array. The cantilever sensor system measures the oscillatory properties generated by the cantilevers within the cantilever array. The system includes the cantilever array and a detection system that measures a signal related to the bending of the cantilever. In addition, optional components such as a high frequency clock, Q-Control, may be added to more accurately measure the oscillation of the cantilevers within the cantilever array.

Abstract: The swivel hinge includes a swivel element with apertures and a base element with a swivel shaft which is journaled for rotation within the apertures. The apertures include radially inwardly extending fingers which position the swivel shaft and are formed as molding gates for molding windows which are provided in common for initially molding the base element and the swivel member as a single integral piece. Subsequent rotation breaks the molding gates and the vestiges form the fingers.

Abstract: In accordance with the objects outlined above, the present invention provides methods of diagnosing individuals at risk for a disease state which results in aberrant Rad51 loci. The methods comprise determining the distribution of Rad51 foci in a first tissue type of a first individual, and then comparing the distribution to the distribution of Rad51 foci from a second normal tissue type from the first individual or a second unaffected individual. A difference in the distributions indicates that the first individual is at risk for a disease state which results in aberrant Rad51 loci. Preferred disease states include cancer and disease states associated with apoptosis.

Abstract: In accordance with the objects outlined above, the present invention provides methods of diagnosing individuals at risk for a disease state which results in aberrant Rad51 loci. The methods comprise determining the distribution of Rad51 foci in a first tissue type of a first individual, and then comparing the distribution to the distribution of Rad51 foci from a second normal tissue type from the first individual or a second unaffected individual. A difference in the distributions indicates that the first individual is at risk for a disease state which results in aberrant Rad51 loci. Preferred disease states include cancer and disease states associated with apoptosis.

Abstract: Compositions and methods are provided for identifying and diagnosing individuals at risk for a disease state associated with aberrant Rad41 foci.

Abstract: The device is a swivel clip or swivel prong with a relatively rotatable swivel and base elements. The swivel element rotates about a shaft which passes through an aperture in the base element. The swivel clip is initially formed in one piece by molding windows in an upper portion of the swivel element which are opposed to molding windows in a lower portion of the swivel element (that is, alternating around the periphery of the shaft). The windows meet in the base member, forming the swivel shaft, the swivel aperture and the internal gates as a single piece. Subsequently breaking the internal gates provides vestiges which support the swivel shaft within the aperture. Radially oriented upwardly extending inverted V-shaped support boss formed on the swivel and base elements position the swivel and base elements with respect to each other.

Abstract: The clip of the present invention includes a plurality of internally threaded legs which form an aperture for receiving an externally threaded stud or similar structural device. A moveable circular collet is attached to a plunger and travels from a pre-driven position wherein the collet is substantially free from engagement with the internally threaded legs and allows for flexure of the internally threaded legs and a fully driven position wherein the collet engages the internally threaded legs in a locked position, inhibiting flexure and engaging the externally threaded stud.

Abstract: The clip includes a body and a lid slidably mounted on tracks on the sides of the lid. A trough formed in the body receives a cylindrical item, such as a rod, pipe or conduit. The lid slides between an open or pre-driven position wherein the lid does not cover the trough, and a closed position wherein the lid covers the trough. The tracks are somewhat inclined with respect to the body so that the lid does not contact the rod in the trough until immediately prior to the closing of the lid. Sloped stop ramps on the body detent engage apertures in the lid in both the open position and the closed position. The underside of the body includes a second trough with a “rabbit ear” detent mechanism to engage a second cylindrical item, such as a rod, pipe or conduit.

Abstract: Compositions and methods are provided for identifying agents which bind to or modulate Rad51.

Abstract: The fastener includes a body and a locking pin. The body includes a base with an aperture therethrough which is aligned with a slot formed between two downwardly extending conjoined arms. The downwardly extending conjoined arms include predrive engagement notches and locking surfaces. The locking pin includes two downwardly extending flexible legs with predrive positioning protrusions. In the predriven position of the fastener, the predrive positioning protrusions are engaged by the predrive engagement notches. In the driven position of the fastener, the predrive positioning protrusions are engaged by the locking surfaces. Additionally, in the driven position, pin retention protrusions on the locking pin are engaged by mating surfaces in the base of the body. The predrive positioning protrusions are formed in a plane which is perpendicular to the plane in which the pin retention protrusions are formed.

Abstract: The swivel hinge includes a swivel element with apertures and a base element with a swivel shaft which is journaled for rotation within the apertures. The apertures include radially inwardly extending fingers which position the swivel shaft and are formed as molding gates for molding windows which are provided in common for initially molding the base element and the swivel member as a single integral piece. Subsequent rotation breaks the molding gates and the vestiges form the fingers.

Abstract: The invention relates to complexes of eukaryotic Rad52 protein and nucleic acids, and methods of using the complexes.

Abstract: The device is a swivel clip with a relatively stationary base element and a relatively rotatable swivel element. The swivel element rotates about a shaft which passes through an aperture in the base element. The swivel clip is initially formed in one piece by molding windows in an upper portion of the swivel element which are opposed to molding windows in a lower portion of the swivel element (that is, alternating around the periphery of the shaft). The windows meet in the base member, forming the swivel shaft, the swivel aperture and the internal gates as a single piece. Subsequently breaking the internal gates provides vestiges which support the swivel shaft within the aperture.

Abstract: The tree fastener includes a shank, a head and wings on first and second opposed sides of the shank. The wings are split along the tool parting line into wing portions which extend from the shank at different angles so that the spacing between wing portions is one half the distance between successive wings. Additionally, the wing portions are diagonally paired so that wing portions on a first opposed side of the shank and a first side of the tool parting line extend from the shank at the same angle as wing portions on a second opposed side of the shank and a second side of the tool parting line. Likewise, wing portions on a second side of the shank and a first side of the tool parting line extend from the shank at the same angle as wing portions on a first side of the shank and a second side of the tool parting line.

Abstract: A nursing bottle helps reduce tooth decay. The nursing bottle contains a first reservoir for water, a second reservoir for a cariogenic liquid, and a nipple with two fluid flow paths. The first fluid flow path runs from the cariogenic liquid reservoir to an outlet opening in the tip of the nipple. The second fluid flow path runs from the water reservoir to lateral outlet openings near the tip of the nipple. When the reservoirs are filled and the bottle is used, the water enters the baby's mouth nearer the teeth than does the cariogenic liquid, thereby rinsing the teeth and reducing tooth decay.

Abstract: A routing clip for fixing at least one conduit to a support is integrally molded from a plastic material and includes U-shaped channels, each having two substantially parallel walls extending therefrom. One of the walls has an inwardly curving projection extending beyond the centerline of the respective U-shaped channel. The inwardly curving projection prevents a tube or conduit, secured within the U-shaped channel, from being readily removed therefrom.

Abstract: A first embodiment of the invention is a clip assembly which includes a hollow cylindrical portion with an unjoined portion along a longitudinal portion of the periphery. Mating elements are formed on both sides of the unjoined portion. In a mated configuration, the mating elements extend radially from the hollow cylindrical portion. The first mating element includes a distal laterally engaging male mating connector and a distal laterally engaging female mating connector longitudinally adjacent thereto. The second mating element includes similar mating connectors but in reverse order so that the female connector of a mating element engages the male connector of the other mating element. The clip assembly further includes panel thickness adjustment wings peripherally adjacent to the mating connectors. The panel thickness adjustment wings flex to engage structural panels of various thicknesses against detent elements.

Abstract: A routing clip for fixing a conduit to a support is integrally molded from a plastic material and includes a U-shaped channel having two substantially parallel walls extending therefrom. Each of the walls has an inwardly curving projection, perhaps reaching or extending beyond the centerline of the U-shaped channel. The inwardly curving projections prevent a tube or conduit, secured within the U-shaped channel, from being readily removed therefrom.