Abstract: The present disclosure relates to methods of treating breast cancer in a patient, comprising administering to the patient a therapeutic combination comprising elacestrant, or a pharmaceutically acceptable salt thereof, and abemaciclib, or a pharmaceutically acceptable salt thereof. The present disclosure also relates to methods of treating breast cancer in a patient that produce a longer Progression Free Survival time as compared to other treatments.

Abstract: The present disclosure relates to methods of treating breast cancer in a patient, comprising administering to the patient a therapeutic combination comprising elacestrant, or a pharmaceutically acceptable salt thereof, and abemaciclib, or a pharmaceutically acceptable salt thereof. The present disclosure also relates to methods of treating breast cancer in a patient that produce a longer Progression Free Survival time as compared to other treatments.

Abstract: A system includes a data shuttle with rows of data storage devices, which are communicatively coupled to a shared printed circuit board assembly. Each row includes multiple data storage devices. The printed circuit board assembly is configured to communicatively couple to a first controller to enable storing data to the data storage devices and to communicatively coupled to a second controller to enable transferring data from the data storage devices.

Abstract: A system includes a data shuttle with rows of data storage devices, which are communicatively coupled to a shared printed circuit board assembly. Each row includes multiple data storage devices. The printed circuit board assembly is configured to communicatively couple to a first controller to enable storing data to the data storage devices and to communicatively coupled to a second controller to enable transferring data from the data storage devices.

Abstract: The present disclosure relates to methods of treating breast cancer in a patient, comprising administering to the patient a therapeutic combination comprising elacestrant, or a pharmaceutically acceptable salt thereof, and abemaciclib, or a pharmaceutically acceptable salt thereof. The present disclosure also relates to methods of treating breast cancer in a patient that produce a longer Progression Free Survival time as compared to other treatments.

Abstract: Techniques are described for improving language translation of content (e.g., web content) on computing devices (e.g., mobile computing devices). For example, automatic translation can be performed when entering reading view in association with displayed web content by determining that the displayed web content is not in a language that is understood by the user (e.g., as indicated by language settings). As another example, language-related meta-data can be passed between applications and used in language detection of content, such as web content.

Abstract: A system running on a mobile device such as a smartphone is configured to expose a user interface (UI) to enable a user to specify web pages that can be pinned to a start screen of the device. Once pinned, the user may launch a web page by voice command from any location on the UI or from within any experience that is currently being supported on the device. Thus, the user can be on a call with a friend talking about a new video game and then use a voice command to launch a web browser application on the mobile device that navigates to a pinned web page having information about the game's release date. Web pages can be readily pinned and unpinned from the start screen through the UI. When a web page is unpinned from the start screen, the system disables voice web navigation for it.

Abstract: A magazine loader for a firearm is provided. The magazine loader includes a base having a lip that is configured to removably engage a magazine in an upstanding position thereon. The base further includes a hydraulic shaft having a first end and a second end, wherein the first end is affixed to the base. The second end includes a depressible platform and a projection configured to load an unloaded cartridge placed above an opening of a magazine. The depressible platform is configured to be hand actuated in relation to the hydraulic shaft to apply downward pressure on the unloaded cartridge with the projection. In this way, the cartridge can be forced downwardly and loaded into the magazine. The depressible platform and projection automatically return to the resting position to allow for additional cartridges to be loaded.

Abstract: A web browser has a user interface that includes a content rendering area within the web browser user interface and a control layout area adjacent the content rendering area. The control layout area includes a user-selectable icon that is always available to the user in the control layout area and which is user-configurable. For example, the user-configurable icon may be configured with one of two pre-defined functions. In one illustrative implementation the two pre-defined functions may be a tabs function and a favorites function.

Abstract: A system running on a mobile device such as a smartphone is configured to expose a user interface (UI) to enable a user to specify web pages that can be pinned to a start screen of the device. Once pinned, the user may launch a web page by voice command from any location on the UI or from within any experience that is currently being supported on the device. Thus, the user can be on a call with a friend talking about a new video game and then use a voice command to launch a web browser application on the mobile device that navigates to a pinned web page having information about the game's release date. Web pages can be readily pinned and unpinned from the start screen through the UI. When a web page is unpinned from the start screen, the system disables voice web navigation for it.

Abstract: Techniques are described for improving language translation of content (e.g., web content) on computing devices (e.g., mobile computing devices). For example, automatic translation can be performed when entering reading view in association with displayed web content by determining that the displayed web content is not in a language that is understood by the user (e.g., as indicated by language settings). As another example, language-related meta-data can be passed between applications and used in language detection of content, such as web content.

Abstract: A web browser has a user interface that includes a content rendering area within the web browser user interface and a control layout area adjacent the content rendering area. The control layout area includes a user-selectable icon that is always available to the user in the control layout area and which is user-configurable. For example, the user-configurable icon may be configured with one of two pre-defined functions. In one illustrative implementation the two pre-defined functions may be a tabs function and a favorites function.

Abstract: A data processing apparatus, comprising a metadata store storing information about files that are stored in a distributed data storage system, and comprising a class database; one or more processing units; logic configured for receiving and storing in the class database a definition of a class of data storage servers comprising one or more subclasses each comprising one or more server selection criteria; associating the class with one or more directories of the data storage system; in response to a data client storing a data file in a directory, binding the class to the data file, determining and storing a set of identifiers of one or more data storage servers in the system that match the server selection criteria, and providing the set of identifiers to the data client.

Abstract: A system and method for enhanced security for a self-checkout system is disclosed where predicted weights of items are used to predict the total order weight. The predicted total order weight is compared to an actual weight of the order based on a weighing of the total order, and an output provided indicating whether the comparison is within acceptable limits or if a security alert or attendant assistance is needed.

Abstract: A data processing apparatus, comprising a metadata store storing information about files that are stored in a distributed data storage system, and comprising a class database; one or more processing units; logic configured for receiving and storing in the class database a definition of a class of data storage servers comprising one or more subclasses each comprising one or more server selection criteria; associating the class with one or more directories of the data storage system; in response to a data client storing a data file in a directory, binding the class to the data file, determining and storing a set of identifiers of one or more data storage servers in the system that match the server selection criteria, and providing the set of identifiers to the data client.

Abstract: A data processing apparatus, comprising a metadata store storing information about files that are stored in a distributed data storage system, and comprising a class database; one or more processing units; logic configured for receiving and storing in the class database a definition of a class of data storage servers comprising one or more subclasses each comprising one or more server selection criteria; associating the class with one or more directories of the data storage system; in response to a data client storing a data file in a directory, binding the class to the data file, determining and storing a set of identifiers of one or more data storage servers in the system that match the server selection criteria, and providing the set of identifiers to the data client.

Abstract: A data processing apparatus, comprising a metadata store storing information about files that are stored in a distributed data storage system, and comprising a class database; one or more processing units; logic configured for receiving and storing in the class database a definition of a class of data storage servers comprising one or more subclasses each comprising one or more server selection criteria; associating the class with one or more directories of the data storage system; in response to a data client storing a data file in a directory, binding the class to the data file, determining and storing a set of identifiers of one or more data storage servers in the system that match the server selection criteria, and providing the set of identifiers to the data client.

Abstract: A structural mechanism for an aircraft includes a support, a hinged surface, and a hinge assembly joining the hinged surface to the support. An actuation system includes an actuator shaft engaged to the hinges and lying coincident with a hinged-surface hinge axis and extending through the aligned center passageways of the hinges of the hinge assembly. A lock is selectively operable to lock the hinged surface to the support when the actuator shaft engages the lock. An actuator structure is controllably operable to move the actuator shaft longitudinally along the hinge-surface hinge axis between a first shaft axial position wherein the actuator shaft engages the lock and the hinges, and a second shaft axial position wherein the actuator shaft does not engage the lock but does engage the hinges, and is controllably operable to rotate the actuator shaft about the hinged-surface hinge axis.

Abstract: A self-checkout system receives a plurality of objects for the identification of each object in the plurality of objects. The system allows security for a collection of the objects and a subset of the collection of objects to be resolved during a self checkout. In order for security to be resolved on an object, a subset of the collection of objects, or a collection of objects the weight detected on a security scale must be equal to the weight of the object, a sum of a subset weight of the collection, or a sum of the collection weight within a given tolerance. If security is not resolved, the system will prevent an additional object from being recognized by the system until the security for the object is resolved.

Abstract: A system and method for enhanced security for a self-checkout system is disclosed where predicted weights of items are used to predict the total order weight. The predicted total order weight is compared to an actual weight of the order based on a weighing of the total order, and an output provided indicating whether the comparison is within acceptable limits or if a security alert or attendant assistance is needed.