Abstract: Trailer mounted portable solar power supplies disclosed can include lights and a backup generator. A solar array with solar panels can be connected to a 360 degree rotatable turntable mounted on a trailer frame enabling the capture of sunlight from all directions. A rotatable telescoping mast with mounted lights can be mounted to the trailer frame. Solar power supply systems can be configured with or without batteries. The AC voltage output can provide electricity for vehicles, homes, buildings, electric vehicles, etc. Portable solar power systems can implement multiple solar arrays to capture more sunlight and generate more electricity. The solar arrays and solar panels are foldable allowing the power system to be retracted for transport. The solar panels can also include sensors to control the positioning of the panels and turn the lights on and off by an onboard computer or wirelessly.

Abstract: Compositions and methods for the treatment of tuberculosis, as well as other mycobacterial and gram positive bacterial infections are disclosed. These compositions contain a highly potent and selective oxazolidinone encapsulated with high efficiency to maximize dosing potential of low toxicity drugs, and are stable in the presence of plasma. The compositions are long circulating and retain their encapsulated drug while in the circulation following intravenous dosing to allow for efficient accumulation at the site of the bacterial or mycobacterial infection. The high doses that can be achieved when combined with the long circulating properties and highly stable retention of the drug allow for a reduced frequency of administration when compared to daily or twice daily administrations of other drugs typically utilized to treat these infections.

Abstract: Compositions and methods for the treatment of tuberculosis, as well as other mycobacterial and gram positive bacterial infections are disclosed. These compositions contain a highly potent and selective oxazolidinone encapsulated with high efficiency to maximize dosing potential of low toxicity drugs, and are stable in the presence of plasma. The compositions are long circulating and retain their encapsulated drug while in the circulation following intravenous dosing to allow for efficient accumulation at the site of the bacterial or mycobacterial infection. The high doses that can be achieved when combined with the long circulating properties and highly stable retention of the drug allow for a reduced frequency of administration when compared to daily or twice daily administrations of other drugs typically utilized to treat these infections.

Abstract: The present disclosure relates to methods of treating a coenzyme A reduction, elevation, sequestration, toxicity, or redistribution (CASTOR) disease such as, for example, defects in fatty acid oxidation enzymes, methylmalonic acidemia, glutaric acidemia, propionic academia, and HMG-CoA lyase, via small molecule modulators of CoA levels. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Abstract: The presently claimed invention relates to aramid pulp comprising a plurality of fibrils having a coating of polyalkyleneimine disposed thereon. The presently claimed invention further relates to a method of coating the aramid pulp with polyalkyleneimine. The presently claimed invention also relates to a rubber composition comprising the coated aramid pulp and rubber as well as to a method for preparing the rubber composition.

Abstract: A method, electromagnetic switch, controller and program product, when energizing an electromagnetic coil to urge a selected shoe into a diverting path downstream of the electromagnetic switch, reverse current flow during at least a portion of the time that the electromagnetic coil is energized to recover energy from the electromagnetic coil.

Abstract: Techniques for flexible, on-site additive manufacturing of components or portions thereof for transport structures are disclosed. An automated assembly system for a transport structure may include a plurality of automated constructors to assemble the transport structure. In one aspect, the assembly system may span the full vertically integrated production process, from powder production to recycling. At least some of the automated constructors are able to move in an automated fashion between the station under the guidance of a control system. A first of the automated constructors may include a 3-D printer to print at least a portion of a component and to transfer the component to a second one of the automated constructors for installation during the assembly of the transport structure. The automated constructors may also be adapted to perform a variety of different tasks utilizing sensors for enabling machine-learning.

Abstract: A computer directs activity within a computer storage subsystem. The computer identifies a computer operating environment including a computer, and a storage subsystem connected to a group of storage devices. The compute receives metadata representing current and historic performance metrics of said computer operating environment. The computer identifies a first device associated with a first behavior profile governed by a power law distribution, and a second device associated with a second behavior profile governed by a normal distribution. The computer trains Machine Learning (ML) models based on the behavior profiles. The computer establishes Device Performance Rules based on the ML models. The computer forecasts time-based storage system requirements based, at least in part on the Device Performance Rules. The computer prefetches data to a cache component based, at least in part on said forecasted system requirements, in accordance with a time reference available to said computer.

Abstract: Compositions and methods for the treatment of tuberculosis, as well as other mycobacterial and gram positive bacterial infections are disclosed. These compositions contain a highly potent and selective oxazolidinone encapsulated with high efficiency to maximize dosing potential of low toxicity drugs, and are stable in the presence of plasma. The compositions are long circulating and retain their encapsulated drug while in the circulation following intravenous dosing to allow for efficient accumulation at the site of the bacterial or mycobacterial infection. The high doses that can be achieved when combined with the long circulating properties and highly stable retention of the drug allow for a reduced frequency of administration when compared to daily or twice daily administrations of other drugs typically utilized to treat these infections.

Abstract: Emmacin-related substituted dihydropyrimidine compounds demonstrate potency at low concentrations and inhibit Methicillin-resistant S. aureus growth.

Abstract: The present disclosure relates to chemical compounds that modulate pantothenate kinase (PanK) activity for the treatment of metabolic disorders (such as diabetes mellitus type II), neurologic disorders (such as pantothenate kinase-associated neurodegeneration), pharmaceutical compositions containing such compounds, and their use in treatment. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Abstract: Techniques for flexible, on-site additive manufacturing of components or portions thereof for transport structures are disclosed. An automated assembly system for a transport structure may include a plurality of automated constructors to assemble the transport structure. In one aspect, the assembly system may span the full vertically integrated production process, from powder production to recycling. At least some of the automated constructors are able to move in an automated fashion between the station under the guidance of a control system. A first of the automated constructors may include a 3-D printer to print at least a portion of a component and to transfer the component to a second one of the automated constructors for installation during the assembly of the transport structure. The automated constructors may also be adapted to perform a variety of different tasks utilizing sensors for enabling machine-learning.

Abstract: Methods, systems, and computer program products for pharmacy substitutions obtain claims data associated with a claim for a prescription associated with a patient; determine, based on the claims data, a universal identifier for the prescription; obtain drug diagnosis data associated with known diagnoses for universal identifiers associated with prescriptions; determine, based on the universal identifier and the drug diagnosis data, a likely diagnosis associated with the prescription; determine, based on the claims data, a cost associated with the likely diagnosis; determine, for the likely diagnosis, using a machine learning model trained based on a training dataset, a potential alternative prescription to the prescription; update, based on user input, the training dataset to include the likely diagnosis associated with the alternative prescription; and train the machine learning model based on the updated training dataset.

Abstract: A method, system and computer program product for data backup based on a workload behavior includes a first computer identifying, using machine learning tools, data associated with frequently accessed files on the first computer by a workload being processed by a second computer. The first computer processes the identified data associated with the frequently accessed files to generate a list of frequently accessed files by the workload, and compares the list of frequently accessed files to backup policy rules active on the first computer. Based on the comparison, the first computer identifies a mismatch between the list of frequently accessed files and the backup policy rules, and specifies a new backup rule to update the backup policy rules for each identified mismatch between the list of frequently accessed files and the backup policy rules.

Abstract: The current disclosure relates to a system and method for secured screen sharing. A specially configured screen sharing server of the system may facilitate screen sharing between two independent and remote devices. The system may be configured to access state information from a primary client device. The system may then determine if any of the elements of the application state primary client interface correspond to sensitive information. The system may then mask the primary client interface to create a replica client interface by masking any elements of the application state that correspond to sensitive information. The system may then cause the replica client device to display the replica client interface by transmitting the application state to the replica client interface.

Abstract: Provided herein are methods and compositions for treating and preventing inflammatory bowel disease.

Abstract: An agricultural product delivery applicator for delivering particulate product to a field. The applicator includes a supply compartment to hold the product and a pneumatic conveying system. The system includes an airflow source to provide an airflow, and a delivery line operably connected to the airflow source and to the supply compartment. The delivery line includes a supply line and a plurality of distribution lines. The system further includes a distributor coupling the supply line with the plurality of distribution lines, a motor disposed on the distribution lines side of the distributor, a shaft assembly rotatable by the motor, and a bearing supporting the shaft assembly on the supply line side of the distributor. The applicator further includes a metering system operably connected between the supply compartment and the pneumatic conveying system. The metering system meters product with the airflow to result in a mixed flow of airflow and product.

Abstract: Systems and Methods of the current disclosure may provide customized webpages. A client device of the system may retrieve a profile corresponding to a user. The client device may further receive a deck including a set of packs, with each pack including a set of cards. As defined herein, a deck corresponds to a workflow (i.e., a series of webpages), while each pack includes context specific user-interface elements which make up a webpage. Further, a card may correspond to one or more elements of the webpage. The client device renders and displays webpages locally by selecting elements to be displayed on the webpage based on a details corresponding to a user of the client device. In other words, the client device creates webpages by selecting one or more cards for each pack of the deck based on details indicated in the profile.

Abstract: A method, electromagnetic switch, controller and program product, when energizing an electromagnetic coil to urge a selected shoe into a diverting path downstream of the electromagnetic switch, reverse current flow during at least a portion of the time that the electromagnetic coil is energized to recover energy from the electromagnetic coil.

Abstract: Compositions and methods for the treatment of tuberculosis, as well as other mycobacterial and gram positive bacterial infections are disclosed. These compositions contain a highly potent and selective oxazolidinone encapsulated with high efficiency to maximize dosing potential of low toxicity drugs, and are stable in the presence of plasma. The compositions are long circulating and retain their encapsulated drug while in the circulation following intravenous dosing to allow for efficient accumulation at the site of the bacterial or mycobacterial infection. The high doses that can be achieved when combined with the long circulating properties and highly stable retention of the drug allow for a reduced frequency of administration when compared to daily or twice daily administrations of other drugs typically utilized to treat these infections.