Abstract: A method is provided for reducing particle formation during manufacture of shell caps for containers such as pharmaceutical containers. The method entails providing a solid polymeric coating on substantially all surfaces of the shell caps to form coated shell caps before permitting the coated shell caps to contact each other or other objects. A pharmaceutical container which employs the shell caps also is provided. The container comprises a vial for storing medicinal compositions therein and a shell cap for sealing the vial. The shell cap includes a hollow metallic preform and a solid polymeric coating which substantially completely encapsulates the preform.

Abstract: A method is provided for reducing particle formation during manufacture of shell caps for containers such as pharmaceutical containers. The method entails providing a solid polymeric coating on substantially all surfaces of the shell caps to form coated shell caps before permitting the coated shell caps to contact each other or other objects. A pharmaceutical container which employs the shell caps also is provided. The container comprises a vial for storing medicinal compositions therein and a shell cap for sealing the vial. The shell cap includes a hollow metallic preform and a solid polymeric coating which substantially completely encapsulates the preform.

Abstract: An apparatus for applying and verifying a printed mark on the periphery of generally cylindrically-shaped objects as they travel on a path. The apparatus comprises at least a first conveyor mounted for movement on a first side of the path. The first conveyor is located to engage the objects to translate the objects at a known translational velocity along the path. A transport assembly is mounted for cyclic movement back and forth along a transport assembly path parallel to the path of the objects at least part of the cyclic movement being approximately at the known translational velocity of the objects. A mark applicator is mounted on the transport assembly and is located in a position to apply a mark on each object as the object is translated by the first conveyor. A sensor is mounted on the transport assembly. The sensor is located in a position to read the applied mark on each object as the object is translated by the belt. The sensor generates a signal representative of the mark.

Abstract: The present invention relates to a combination container for holding sterilized elements and a sterilizable transfer port for transferring the sterilized elements into an isolation system having a wall. The container includes a flexible bag defining a cavity containing a plurality of the sterilized elements. The container also includes a collar which has an interior surface defining a bore extending through the collar. The bag is secured to the collar with the opening in registry with the bore. A removable seal is movable between a first position where the seal initially extends across the bore to prevent elements from being removed from the cavity and to maintain the sterility of the elements and a second position where the seal is moved from the first position to access the cavity such that the elements are removable from the cavity through the opening and the bore.

Abstract: A system for pharmaceutical product identification, comprising a closure on a pharmaceutical container, including a cap seal having a dependent skirt and an upwardly facing top. The seal has a first identifying indicia and the removable overcap protecting the closure has a second identifying indicia thereon. The first and second indicia cooperatively conveying information to the user of said container.

Abstract: A system for pharmaceutical product identification, comprising a closure on a pharmaceutical container, including a cap seal having a dependent skirt and an upwardly facing top. The seal has a first identifying indicia and the removable overcap protecting the closure has a second identifying indicia thereon. The first and second indicia cooperatively conveying information to the user of said container.