Patents by Inventor Charles Peter Woloshuk

Charles Peter Woloshuk has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Transgenic fungal resistant plants expressing chitinase and glucanase, process for obtaining, and recombinant polynucleotides for uses therein
    Patent number: 6087560
    Abstract: Plants are provided with improved resistance against pathogenic fungi. They are genetically transformed with one or more polynucleotides which essentially comprise one or more genes encoding plant chitinases and .beta.-1,3-glucanases. Preferred are the intracellular forms of the said hydrolytic enzymes, especially preferred are those forms which are targeted to the apoplastic space of the plant by virtue of the modification of the genes encoding the said enzymes. Particularly preferred are plants exhibiting a relative overexpression of at least one gene encoding a chitinase and one gene encoding a .beta.-1,3-glucanase.
    Type: Grant
    Filed: February 18, 1997
    Date of Patent: July 11, 2000
    Assignees: Rijksuniversiteit te Leiden, Mogen International, N.V.
    Inventors: Bernardus J. C. Cornelissen, Leo Sjoerd Melchers, Elisabeth J. S. Meulenhoff, Jeroen S. C. van Roekel, Marianne Beatrix Sela-Buurlage, Alexandra Aleida Vloemans, Charles Peter Woloshuk, John Ferdinand Bol, Hubertus J. M. Linthorst
  • Antifungal preparations containing osmotin
    Patent number: 5856151
    Abstract: A method for inhibiting the growth and/or germination of a fungus that is susceptible to an osmotin protein by contacting the fungus, or causing the fungus to be contacted with, an effective amount of an osmotin protein. The fungus can be, for example, a plant pathogenic fungus, such as an Oomycete. In one embodiment of the invention, the effective amount of the osmotin protein is produced by a plant having incorporated into its genome a chimeric gene having a) an open reading frame encoding the osmotin protein, or a precursor of the osmotin protein, and having operably linked thereto b) a regulatory region which causes the chimeric gene to be expressed in the plant.
    Type: Grant
    Filed: September 30, 1994
    Date of Patent: January 5, 1999
    Assignee: Mogen International, N.V.
    Inventors: Charles Peter Woloshuk, Leo Sjoerd Melchers, Bernardus Johannes Clemens Cornelissen, Elisabeth Josine Sophie Meulenhoff, Petrus Josephus Maria Van Den Elzen
  • Fungal resistant plants, process for obtaining fungal resistant plants and recombinant polynucleotides for use therein
    Patent number: 5670706
    Abstract: Plants are provided with improved resistance against pathogenic fungi. They are genetically transformed with one or more polynucleotides which essentially comprise one or more genes encoding plant chitinases and .beta.-1,3-glucanases. Preferred are the intracellular forms of the said hydrolytic enzymes, especially preferred are those forms which are targeted to the apoplastic space of the plant by virtue of the modification of the genes encoding the said enzymes. Particularly preferred are plants exhibiting a relative overexpression of at least one gene encoding a chitinase and one gene encoding a .beta.-1,3-glucanase.
    Type: Grant
    Filed: April 19, 1993
    Date of Patent: September 23, 1997
    Assignees: MOGEN International, n.v., Rijksuniversiteit te Leiden
    Inventors: Bernardus J. C. Cornelissen, Leo Sjoerd Melchers, Elisabeth J. S. Meulenhoff, Jeroen S. C. van Roekel, Marianne Beatrix Sela-Buurlage, Alexandra Aleida Vloemans, Charles Peter Woloshuk, John Ferdinand Bol, Hubertus J. M. Linthorst