Patents by Inventor Charles R. Heap

Charles R. Heap has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TERPENOPHENOLIC COMPOUNDS AND THEIR USE
    Publication number: 20230225985
    Abstract: The present disclosure describes terpenophenolic compounds and their use in medicine. The present disclosure further describes perrottetinene-like compounds, the manufacture thereof, formulations containing same and their use in medicine. Such compounds include (1?R,2?R)-5?-methyl-phenethyl-2?-(prop-1-ene-2-yl)-1?,2?,3?,4?-tetrahydro-[1,1?-biphenyl]-2,6-diol (CBD-PET) or (1?R,2?R)-4-(4-hydroxyphenethyl)-5?-methyl-2?-(prop-1-ene-2-yl)-1?,2?,3?,4?-tetrahydro-[1,1?-biphenyl]-2,6-diol (CBD-PET-OH).
    Type: Application
    Filed: September 30, 2022
    Publication date: July 20, 2023
    Inventors: Colin George Stott, Charles R. Heap, Ramamoorthy Gurusankar
  • IMIDAZO(4,5-B) PYRIDIN-2-YL AMIDES AS KV7 CHANNEL ACTIVATORS
    Publication number: 20170240547
    Abstract: Compounds represented by formula 1 can be potent and/or partially selective for the Kv7.2/7.3 heteromultimer. They may be useful in treating disorders related to seizures, pain, neurotransmitter release, etc.
    Type: Application
    Filed: May 10, 2017
    Publication date: August 24, 2017
    Inventors: Lynn Resnick, George T. Topalov, Steven A. Boyd, Justin K. Belardi, Charles A. Flentge, James S. Hale, Scott S. Harried, David A. Mareska, Kai Zhang, Charles R. Heap, Mark Hadden, Wenge Cui, Hélène Decornez, Shuang Liu
  • Imidazo(4,5-) pyridin-2-yl amides as K7 channel activators
    Patent number: 9650376
    Abstract: Compounds represented by formula 1 can be potent and/or partially selective for the Kv7.2/7.3 heteromultimer. They may be useful in treating disorders related to seizures, pain, neurotransmitter release, etc.
    Type: Grant
    Filed: March 17, 2014
    Date of Patent: May 16, 2017
    Assignee: KNOPP BIOSCIENCES LLC
    Inventors: Lynn Resnick, George T. Topalov, Steven A. Boyd, Justin K. Belardi, Charles A. Flentge, James S. Hale, Scott S. Harried, David A. Mareska, Kai Zhang, Charles R. Heap, Mark Hadden, Wenge Cui, Hélène Decornez, Shuang Liu
  • IMIDAZO(4,5-B) PYRIDIN-2-YL AMIDES AS KV7 CHANNEL ACTIVATORS
    Publication number: 20160031875
    Abstract: Compounds represented by formula 1 can be potent and/or partially selective for the Kv7.2/7.3 heteromultimer. They may be useful in treating disorders related to seizures, pain, neurotransmitter release, etc.
    Type: Application
    Filed: March 17, 2014
    Publication date: February 4, 2016
    Inventors: Lynn Resnick, George T. Topalov, Steven A. Boyd, Justin K. Belardi, Charles A. Flentge, James S. Hale, Scott S. Harried, David A. Mareska, Kai Zhang, Charles R. Heap, Mark Hadden, Wenge Cui, Hélène Decornez, Shuang Liu