Patents by Inventor Charles R. Scaf

Charles R. Scaf has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for searching polynucleotide probe targets in databases
    Patent number: 7085652
    Abstract: Methods for determining the binding affinity of a probe to a target or targets in a polynucleotide composite using an automated system. Such methods determine relative binding sites based on thermodynamic principles, using a thermodynamic alphabet and a thermodynamic scoring matrix, with appropriate computer software, such as BLASTP. The invention also provides methods for designing polynucleotide probes to be used in hybridization assays, and minimizing the occurrence of cross-hybridization.
    Type: Grant
    Filed: February 14, 2003
    Date of Patent: August 1, 2006
    Assignee: Applera Corporation
    Inventors: Charles R. Scaf, Nicolas Peyret, Francisco M. De La Vega, Ryan T. Koehler, Eugene G. Spier