Abstract: A portable aircraft stretcher for supporting a person on an aircraft, the stretcher configured for location in a port-starboard orientation across three or four side-by-side commercial aircraft seats. The stretcher includes a seat and a backrest. The backrest has a reclined orientation for supporting the person in a reclined position across and above the three or four aircraft seats. The stretcher further includes a support member extending downwardly from the backrest for supporting the backrest. The stretcher further includes a harness for securing the person to the stretches and one or more connection points configured to engage with at least one aircraft seatbelt of the three or four aircraft seats for securing the stretcher to the aircraft seats.

Abstract: The present invention relates to vaccine compositions comprising Norovirus antigens and adjuvants, in particular, mixtures of monovalent VLPs and mixtures of multivalent VLPs, and to methods of conferring protective immunity to Norovirus infections in a human subject.

Abstract: The present disclosure relates to targeting SARS-CoV-2, in particular, prevalent strains of SARS-CoV-2, and methods of using such vaccines to induce neutralizing antibody levels against SARS-CoV-2.

Abstract: A disc golf disc stand is provided. The disc golf disc stand includes a stand base. The stand base includes a base coupling connected to a basal periphery by at least one coupling support. The basal periphery is configured to rest on a surface, such as the ground. A stand upright is secured to the base coupling and extends vertically upwardly therefrom. A disc stack holder is coupled with the stand upright and includes a stack holder base or plate and at least one stack rest. The disc golf disc stand is configured to carry at least one disc on the stack holder base and stack rest.

Abstract: Disclosed is a method of making a nanostructure by solubilizing a recombinant component B (compB) protein from inclusion bodies with a solubilization solution, thereby generating a product sample comprising product compB protein.

Abstract: The present invention relates to vaccine compositions comprising Norovirus antigens and adjuvants, in particular, mixtures of monovalent VLPs and mixtures of multivalent VLPs, and to methods of conferring protective immunity to Norovirus infections in a human subject.

Abstract: The present invention relates to single dose parenteral vaccine compositions comprising mixtures of monovalent Norovirus virus-like particles. Methods of conferring protective immunity against Norovirus infections in a human subject by administering such compositions are also disclosed.

Abstract: Disclosed are methods of a method of making a nanostructure, comprising adding a component A (compA) protein to a solution comprising a component B (compB) protein under conditions that minimize shear stress, thereby forming a compA:compB complex. Further disclosed are methods of making a nanostructure, comprising (i) providing a first inlet fluid stream comprising a first protein and a second inlet fluid stream comprising a second protein, and (ii) contacting the first inlet fluid stream and the second inlet fluid stream to form an outlet stream, wherein mixing of the first protein and the second protein occurs in the outlet stream, thereby forming a protein complex comprises the first protein and the second protein. A microfluidic mixer may be used. The methods may further comprise purifying the compA:compB complex from excess compA, excess compB, and/or other impurities by filtering the solution with a 1,000 kDa membrane or an equivalent thereof.

Abstract: The present invention relates to single dose parenteral vaccine compositions comprising mixtures of monovalent Norovirus virus-like particles. Methods of conferring protective immunity against Norovirus infections in a human subject by administering such compositions are also disclosed.

Abstract: Embodiments of this application disclose a manufacturer usage description (MUD) file obtaining method and a device. A MUD controller uses a verified valid MUD uniform resource locator (URL) as a trusted basis. When a terminal device is currently updated, the MUD controller obtains a new MUD file based on a new MUD URL that meets a matching condition with the trusted MUD URL. Alternatively, the MUD controller uses fixed attribute information of a valid MUD URL as a trusted basis. When a terminal device is currently updated, the MUD controller obtains an updated MUD URL based on the trusted fixed attribute information and newly received variable attribute information, and obtains a new MUD file.

Abstract: The disclosure relates to a modified adeno-associated virus (AAV) vector for treating various pathologies. The modified AAV vector may include transfected Claudin genes for use in treating those pathologies via the disclosed gene therapy. The disclosure also relates to the methods of preparing, administering, and testing the disclosed genetic therapies. Furthermore, the disclosure relates to systems and methods for monitoring, locally or remotely, a patient's medical condition and the efficacy of an administered genetic therapy. The system and methods also disclose adjusting the genetic therapies based on established operating parameters.

Abstract: The disclosure relates to an effervescent therapeutic composition for delivering multiple compounds to a patient in a single administration. In some embodiments, the effervescent therapeutic composition includes an alkaline effervescing compound, one or more compressible binders, a pharmaceutically acceptable salt of metformin, a pharmaceutically acceptable cobalamin, and an acid compound or an acid salt. In other embodiments, the effervescent therapeutic composition may include a folate or folic acid and metformin. In yet other embodiments, the effervescent therapeutic composition may include a folate or folic acid, cobalamin, and metformin.

Abstract: The present invention relates to vaccine compositions comprising Norovirus antigens and adjuvants, in particular, mixtures of monovalent VLPs and mixtures of multivalent VLPs, and to methods of conferring protective immunity to Norovirus infections in a human subject.

Abstract: The present invention relates to vaccine compositions comprising Norovirus antigens and adjuvants, in particular, mixtures of monovalent VLPs and mixtures of multivalent VLPs, and to methods of conferring protective immunity to Norovirus infections in a human subject.

Abstract: The present invention relates to vaccine compositions comprising Norovirus antigens and adjuvants, in particular, mixtures of monovalent VLPs and mixtures of multivalent VLPs, and to methods of conferring protective immunity to Norovirus infections in a human subject.

Abstract: Methods for purifying human Calciviruses are disclosed, including Noroviruses and Sapoviruses.

Abstract: The present invention relates to vaccine compositions comprising Norovirus antigens and adjuvants, in particular, mixtures of monovalent VLPs and mixtures of multivalent VLPs, and to methods of conferring protective immunity to Norovirus infections in a human subject.

Abstract: The present invention relates to single dose parental vaccine compositions comprising mixtures of monovalent Norovirus virus-like particles. Methods of conferring protective immunity against Norovirus infections in a human subject by administering such compositions are also disclosed.

Abstract: The present invention relates to antigenic and vaccine compositions comprising Norovirus antigens and adjuvants, in particular, mixtures of monovalent VLPs and mixtures of multivalent VLPs, and to a process for the production of both monovalent and multivalent VLPs, the VLPs comprising capsid proteins from one or more Norovirus genogroups.

Abstract: The present invention relates to vaccine compositions comprising Norovirus antigens and adjuvants, in particular, mixtures of monovalent VLPs and mixtures of multivalent VLPs, and to methods of conferring protective immunity to Norovirus infections in a human subject.