Patents by Inventor Charles Rodi

Charles Rodi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tagging and assessing a target sequence
    Patent number: 10619163
    Abstract: Provided in certain aspects are methods for dynamically adding molecular indexes to nucleic acid, and optionally analyzing the tagged nucleic acid. Also provided in certain aspects are methods for producing a single-stranded nucleic acid molecule from two molecules. The first molecule typically is a single-stranded nucleic acid (ssNA) containing a target sequence with optional linked nucleic acid sequences. The second molecule typically is a ssNA containing a target binding sequence and a nucleic acid sequence “tag” that is not complementary to the target sequence.
    Type: Grant
    Filed: July 2, 2015
    Date of Patent: April 14, 2020
    Assignee: RHODX, Inc.
    Inventor: Charles Rodi
  • TAGGING AND ASSESSING A TARGET SEQUENCE
    Publication number: 20170121716
    Abstract: Provided in certain aspects are methods for dynamically adding molecular indexes to nucleic acid, and optionally analyzing the tagged nucleic acid. Also provided in certain aspects are methods for producing a single-stranded nucleic acid molecule from two molecules. The first molecule typically is a single-stranded nucleic acid (ssNA) containing a target sequence with optional linked nucleic acid sequences. The second molecule typically is a ssNA containing a target binding sequence and a nucleic acid sequence “tag” that is not complementary to the target sequence.
    Type: Application
    Filed: July 2, 2015
    Publication date: May 4, 2017
    Inventor: Charles Rodi
  • DETECTION OF NUCLEIC ACIDS IN URINE
    Publication number: 20160002740
    Abstract: Provided are methods of determining whether a subject comprises a target nucleic acid sequence that is 51-110 nucleotides in length. Also provided are methods of monitoring a condition or treatment effect in a subject.
    Type: Application
    Filed: August 20, 2015
    Publication date: January 7, 2016
    Inventors: Cecile Rose Vibat, Vlada Melnikova, Charles Rodi
  • Methods for generating databases and databases for identifying polymorphic genetic markers
    Patent number: 8818735
    Abstract: Processes and methods for creating a database of genomic samples from healthy human donors, methods that use the database to identify and correlate polymorphic genetic markers and other markers with diseases and conditions are provided.
    Type: Grant
    Filed: June 28, 2012
    Date of Patent: August 26, 2014
    Assignee: Sequenom, Inc.
    Inventors: Andreas Braun, Hubert Köster, Dirk Johannes Van Den Boom, Ping Yip, Charles Rodi, Liyan He, Norman Chiu, Christian Jurinke
  • Methods for generating databases and databases for identifying polymorphic genetic markers
    Patent number: 8229677
    Abstract: Processes and methods for creating a database of genomic samples from healthy human donors, methods that use the database to identify and correlate polymorphic genetic markers and other markers with diseases and conditions are provided.
    Type: Grant
    Filed: December 21, 2009
    Date of Patent: July 24, 2012
    Assignee: Sequenom, Inc.
    Inventors: Andreas Braun, Hubert Koster, Dirk Van den Boom, Ping Yip, Charles Rodi, Liyan He, Norman Chiu, Christiane Jurinke
  • Method for Displaying Antibodies
    Publication number: 20110250642
    Abstract: There is disclosed vector designs, constructs and approaches to construct antibody libraries that display antibodies, such as full-length immunoglobulins, single chain antibody (SCA) scFv, or Fab on the host cell surface. There is also disclosed screening approaches to isolate desired antibody binders from above mentioned antibody libraries for selective antibody targets.
    Type: Application
    Filed: April 12, 2011
    Publication date: October 13, 2011
    Inventors: Henry Ji, Heyue Zhou, Yanliang Zhang, Charles Rodi
  • Biomarkers and assays for carcinogenesis
    Publication number: 20060063177
    Abstract: The present invention relates to carcinogenesis biomarkers produced by phenobarbitol-treated rat hepatocytes, nucleic acid molecules that encode carcinogenesis biomarkers or a fragment thereof and nucleic acid molecules that are useful as probes or primers for detecting or inducing carcinogenesis, respectively. The invention also relates to applications of the factor or fragment such as forming antibodies capable of binding the carcinogenesis biomarkers or fragments thereof.
    Type: Application
    Filed: July 25, 2005
    Publication date: March 23, 2006
    Inventors: Roderick Bunch, Dale Morris, Sandra Curtiss, Charles Rodi