Abstract: A biocompatible gel matrix that is produced from an emulsion comprising a water-soluble material capable of forming a gel and a biocompatible hydrophobic substance is provided. In certain aspects. the biocompatible gel matrix of the present disclosure may include a plurality of microchannels and a plurality of nanochannels, wherein the plurality of microchannels and the plurality of nanochannels are not patterned microchannels and nanochannels: and a plurality of cells, wherein the cells are adjacent the plurality of microchannels and wherein a majority of the plurality of cells are within a distance of 50 microns or less from at least one of the plurality of microchannels. wherein the plurality of microchannels have a width of 5-500 microns and the plurality of nanochannels have a width of 1 nm-500 nm. Methods of using the matrix and methods of making the matrix are also provided.

Abstract: A method and system of supplementing a main illuminating light with a supplementary illuminating light using a plurality of solid-state light emitters to illuminate a space according to a target illumination spectrum are provided. The method can include determining or receiving a reference illumination spectrum associated with the main illuminating light. The method can also include determining a spectral deviation between the reference illumination spectrum and the target illumination spectrum. The method can further include controlling the solid-state light emitters to emit respective emitter beams forming the supplementary illuminating light and illuminating the space along with the main illuminating light, the emitter beams having respective emitter spectra together defining a supplementary illumination spectrum of the supplementary illuminating light.

Abstract: An off-road vehicle has a frame, a motor, a steering input device, a storage bin disposed forward of the steering input device, the storage bin having side walls and a bottom wall, and an accessory holder assembly connected to the storage bin. The accessory holder assembly includes a receptacle having an upwardly facing receptacle aperture for receiving an accessory. The receptacle aperture is disposed within a perimeter defined by the side walls of the storage bin. The receptacle extends below the bottom wall of the storage bin. A height of a portion of the receptacle extending below the bottom wall of the storage bin being greater than a width of the receptacle aperture and greater than a length of the receptacle aperture.

Abstract: Described herein is a therapeutic method that specifically addresses tumor-infiltrated regulatory T cells (Tregs) with minimal impact on the peripheral Tregs.

Abstract: Bioartificial ultrafiltration devices comprising a scaffold comprising a population of cells enclosed in a matrix and disposed adjacent a plurality of channels are provided. The population of cells provides molecules such as therapeutic molecules to a subject in need thereof and is supported by the nutrients filtered in an ultrafiltrate from the blood of the subject. The plurality of channels in the scaffold facilitate the transportation of the ultrafiltrate and exchange of molecules between the ultrafiltrate and the population of cells.

Abstract: Disclosed here is a system to enable interaction between a user with a disability and a computer program. The system can obtain a representation of a user interface to present to a user. The system can determine an element associated with the user interface, where the element is configured to provide information to the user, however, the user interface presentation of the element at least partially fails to provide the information to the user. Based on the element, the system can determine an appropriate test to perform. The appropriate test indicates at least two of: a test to perform with a keyboard, a gesture test to perform with a mobile screen reader, and an audio test to perform with a screen reader. The system can generate an indication of the appropriate test. The system can provide the indication of the appropriate test prior to releasing the user interface to the user.

Abstract: A track assembly is to be mounted on a drive axle of a vehicle. The track assembly has a frame, at least one leading idler wheel mounted to the front of the frame for rotation about a transverse leading idler wheel axis, at least one trailing idler wheel mounted to the rear of the frame for rotation about a traverse trailing idler wheel axis parallel to the leading idler wheel axis, and a single drive wheel assembly. The drive wheel assembly includes a sub-frame removably securable to the frame in any one of a plurality of longitudinal securement positions on the frame, and a drive wheel rotationally mounted on the sub-frame for rotation about a drive wheel axis. The drive wheel is operatively connectable to the drive axle of the vehicle. A pair of track assemblies is also described. A vehicle having the pair of track assemblies is also described.

Abstract: A track assembly for a vehicle includes: a frame; a plurality of track-contacting wheels; an endless track disposed around the track-contacting wheels; a rotation limiting device for limiting rotation of the track assembly relative to a vehicle frame; a connection bracket for connecting the rotation limiting device to the frame; and a bushing assembly slidably connecting a device connecting end of the connection bracket to an elongate support of the rotation limiting device. The bushing assembly includes an inner bushing slidably mounted to the elongate support, an outer bushing affixed to the device connecting end, and a resilient element connected between the bushings. The resilient element is resiliently deformable such that: the inner bushing is rotatable relative to the outer bushing such that an inner bushing axis can be angled relative to an outer bushing axis; and the inner bushing is axially movable relative to the outer bushing.

Abstract: A track assembly for a vehicle is provided. The vehicle has a suspension arm for connecting the track assembly to the vehicle. The track assembly includes a frame, a plurality of track-contacting wheels, and an endless track disposed around the track-contacting wheels. The track-contacting wheels include: a drive wheel rotationally connected to the frame and at least one idler wheel rotationally connected to the frame. The drive wheel defines a drive wheel axis about which the drive wheel is rotatable. The drive wheel is adapted for driving the endless track. The track assembly also includes a rotation limiting device for limiting rotation of the track assembly relative to the suspension arm of the vehicle. The rotation limiting device is connected to the frame of the track assembly and is configured to be connected to the suspension arm of the vehicle.

Abstract: An off-road vehicle has a frame, a motor, a steering input device, a storage bin disposed forward of the steering input device, the storage bin having side walls and a bottom wall, and an accessory holder assembly connected to the storage bin. The accessory holder assembly includes a receptacle having an upwardly facing receptacle aperture for receiving an accessory. The receptacle aperture is disposed within a perimeter defined by the side walls of the storage bin. The receptacle extends below the bottom wall of the storage bin. A height of a portion of the receptacle extending below the bottom wall of the storage bin being greater than a width of the receptacle aperture and greater than a length of the receptacle aperture.

Abstract: Disclosed here is a system to enable interaction between a user with a disability and a computer program. The system can obtain a representation of a user interface to present to a user. The system can determine an element associated with the user interface, where the element is configured to provide information to the user, however, the user interface presentation of the element at least partially fails to provide the information to the user. Based on the element, the system can determine an appropriate test to perform. The appropriate test indicates at least two of: a test to perform with a keyboard, a gesture test to perform with a mobile screen reader, and an audio test to perform with a screen reader. The system can generate an indication of the appropriate test. The system can provide the indication of the appropriate test prior to releasing the user interface to the user.

Abstract: A method for mounting a track assembly to a vehicle comprises: pivotally connecting a frame of the track assembly to a distal end portion of an A-arm of the vehicle for permitting rotation of the track assembly about a steering axis; inserting a fastener through a fastener aperture defined in the distal end portion of the A-arm; and fastening an anti-rotation device of the track assembly to the distal end portion of the A-arm with the fastener, the anti-rotation device being connected to the frame. A suspension and track assembly for a vehicle is also disclosed.

Abstract: A loading system for a vehicle includes a buggy for transporting cargo and a mounting assembly for loading the buggy onto the vehicle. A buggy frame has an elongated member. The mounting assembly is configured to be connected to the vehicle and has a sliding rail configured to slidingly receive the elongated member of the buggy frame to allow the buggy to slide along the sliding rail. The sliding rail has a first portion and a second portion extending at an angle relative to the first portion such that, when the mounting assembly is connected to the vehicle, the first portion extends generally horizontally and the second portion extends downwardly from the first portion. The second portion is configured to slide the buggy upwards onto the vehicle. The first portion being configured to slide the buggy generally horizontally into a loaded position on the vehicle.

Abstract: Disclosed here is a system to enable interaction between a user with a disability and a computer program. The system can obtain a representation of a user interface to present to a user. The system can determine an element associated with the user interface, where the element is configured to provide information to the user, however, the user interface presentation of the element at least partially fails to provide the information to the user. Based on the element, the system can determine an appropriate test to perform. The appropriate test indicates at least two of: a test to perform with a keyboard, a gesture test to perform with a mobile screen reader, and an audio test to perform with a screen reader. The system can generate an indication of the appropriate test. The system can provide the indication of the appropriate test prior to releasing the user interface to the user.

Abstract: An implement connection system for connecting an implement to a vehicle. The implement connection system includes a pin having a distal portion defining a distal end of the pin and a proximal portion defining a proximal end of the pin. The distal portion is adapted to be received by an implement connector. The implement connection system also includes a fastener extending into the pin for removably fastening the pin to a portion of the vehicle. The proximal end is disposed between the distal end and the portion of the vehicle when the pin is fastened to the portion of the vehicle.

Abstract: A loading system for a vehicle includes a buggy for transporting cargo and a mounting assembly for loading the buggy onto the vehicle. A buggy frame has an elongated member. The mounting assembly is configured to be connected to the vehicle and has a sliding rail configured to slidingly receive the elongated member of the buggy frame to allow the buggy to slide along the sliding rail. The sliding rail has a first portion and a second portion extending at an angle relative to the first portion such that, when the mounting assembly is connected to the vehicle, the first portion extends generally horizontally and the second portion extends downwardly from the first portion. The second portion is configured to slide the buggy upwards onto the vehicle. The first portion being configured to slide the buggy generally horizontally into a loaded position on the vehicle.

Abstract: A track assembly for a vehicle has a frame; a drive wheel rotatably mounted to the frame; an idler wheel mount pivotally connected to the frame, the idler wheel mount being selectively pivotable between an operating position and a released position; a lock selectively locking the idler wheel mount in the operating position; an idler wheel rotationally connected to the idler wheel mount, the idler wheel being pivotable with the idler wheel mount; and an endless track driven by the drive wheel around the frame. In the operating position of the idler wheel mount, the idler wheel tensions the endless track. Pivoting the idler wheel mount from the operating position to the released position releases at least some tension from the endless track. A vehicle having the track assembly and a method for installing an endless track having derailed from other components of a track assembly are also disclosed.

Abstract: A track assembly is to be mounted on a drive axle of a vehicle. The track assembly has a frame, at least one leading idler wheel mounted to the front of the frame for rotation about a transverse leading idler wheel axis, at least one trailing idler wheel mounted to the rear of the frame for rotation about a traverse trailing idler wheel axis parallel to the leading idler wheel axis, and a single drive wheel assembly. The drive wheel assembly includes a sub-frame removably securable to the frame in any one of a plurality of longitudinal securement positions on the frame, and a drive wheel rotationally mounted on the sub-frame for rotation about a drive wheel axis. The drive wheel is operatively connectable to the drive axle of the vehicle. A pair of track assemblies is also described. A vehicle having the pair of track assemblies is also described.

Abstract: A clamping and cutting device that has a blade and blade receptacle aspect of the cutting mechanism with open clamping mechanisms that are actuated in a step-wise fashion due to a mechanical timing mechanism.

Abstract: Apparatus and methods advantageously maintain transistors of open-drain differential pairs biased in the saturation region when “active,” rather in than the triode or linear region. The biasing techniques are effective over a broad range of process, voltage, and temperature (PVT) variations. By controlling a high voltage level used to drive the gate of a transistor of the differential pair, the biasing of the transistor in the saturation region is maintained. In one embodiment, the low voltage level used to cut off the transistor of the differential pair is also controlled. These techniques advantageously permit differential drivers to exhibit relatively large output swings, relatively high edge rates, relatively high return loss, and relatively good efficiency.