Abstract: Oligonucleotide analogues comprising modified intersubunit linkages and/or modified 3? and/or 5?-end groups are provided. The disclosed compounds are useful for the treatment of diseases where inhibition of protein expression or correction of aberrant mRNA splice products produces beneficial therapeutic effects.

Abstract: Oligonucleotide analogues comprising modified intersubunit linkages and/or modified 3? and/or 5?-end groups are provided. The disclosed compounds are useful for the treatment of diseases where inhibition of protein expression or correction of aberrant mRNA splice products produces beneficial therapeutic effects.

Abstract: Oligonucleotide analogues comprising modified intersubunit linkages and/or modified 3? and/or 5?-end groups are provided. The disclosed compounds are useful for the treatment of diseases where inhibition of protein expression or correction of aberrant mRNA splice products produces beneficial therapeutic effects.

Abstract: Oligonucleotide analogs comprising modified intersubunit linkages and/or modified 3? and/or 5?-end groups are provided. The disclosed compounds are useful for the treatment of diseases where inhibition of protein expression or correction of aberrant mRNA splice products produces beneficial therapeutic effects.

Abstract: Oligonucleotide analogues comprising modified intersubunit linkages and/or modified 3? and/or 5?-end groups are provided. The disclosed compounds are useful for the treatment of diseases where inhibition of protein expression or correction of aberrant mRNA splice products produces beneficial therapeutic effects.

Abstract: Oligonucleotide analogs comprising modified intersubunit linkages and/or modified 3? and/or 5?-end groups are provided. The disclosed compounds are useful for the treatment of diseases where inhibition of protein expression or correction of aberrant mRNA splice products produces beneficial therapeutic effects.

Abstract: Oligonucleotide analogues comprising modified intersubunit linkages and/or modified 3? and/or 5?-end groups are provided. The disclosed compounds are useful for the treatment of diseases where inhibition of protein expression or correction of aberrant mRNA splice products produces beneficial therapeutic effects.

Abstract: The invention concerns an anode straightening apparatus (10, 30, 60) for the straightening of an anode (100) typically used in an electrowinning process. In the preferred embodiment the apparatus includes clamps (21, 41, 71) for clamping a busbar (101) of the anode and clamps (22, 42, 71) for clam in a blade of the anode to the apparatus during the course of the straightening process. At least one sensor (29, 52, 85) monitors the curvature of the blade (102) of the anode (100) when the anode is secured to the apparatus by the clamps. The apparatus ((10, 30, 60) includes a movable head (24, 44, 78) housing straightening means for bending the anode in a desired direction in response to feedback received from the sensor. The head is movable in two planes of movement which are transverse to one another.

Abstract: Oligonucleotide analogues comprising modified intersubunit linkages and/or modified 3? and/or 5?-end groups are provided. The disclosed compounds are useful for the treatment of diseases where inhibition of protein expression or correction of aberrant mRNA splice products produces beneficial therapeutic effects.

Abstract: Oligonucleotide analogues comprising modified intersubunit linkages and/or modified 3? and/or 5?-end groups are provided. The disclosed compounds are useful for the treatment of diseases where inhibition of protein expression or correction of aberrant mRNA splice products produces beneficial therapeutic effects.

Abstract: A method of routing in a computer network having a pool of servers capable of servicing requests for access to a set of server resource objects. The set of server resource objects are distributed in a non-homogeneous manner across the server pool. According to the method, each incoming client request for access to a specified server resource object is targeted to a router having an associated port space identifying a plurality of ports. Based on the port on which an incoming client request is received, the request is mapped to one of the server resource objects. The router then selects the “best provider” and redirects or forwards the request to that server. The routing and redirection is based upon the port for the incoming request.

Abstract: An absorbent wiping band that is specifically adapted to be releasably and conformably fastened around the forearm, elbow and upper arm to expose an absorbent strip of material extending upwardly along the upper arm beginning at the elbow such that when the arm is straightened the absorbent band is even with the wearer's forehead and can be manipulated to wipe the forehead for removal of perspiration.

Abstract: A method of dynamically generating a Web page at a Web server in response to an HTTP request from a Web client in a computer network. The Web page has a hypertext reference identifying a linked page supported on each of a set of other servers in the computer network. In response to the request, a given one of the set of other servers is identified based on some given criteria, e.g., shortest access time, lightest current load, or the like. Information identifying a path to the identified other server is then inserted into the hypertext reference as the Web page (including the hypertext reference) is returned to the Web client in response to the request. Thus, if the hypertext reference is later activated by the user browsing the returned Web page, the linked page is preferentially served from the identified other server.

Abstract: One or more policies are implemented at a Web browser to enhance access to Web servers that host content requested by the browser. When the browser issues a request, a name service returns a list of IP addresses that may service that request. The list is configured as "random" or "ordered" according to a given naming convention or other local policy, and IP addresses are selected from the list at random or in order (as the case may be) until a connection to an appropriate server is obtained. The browser remembers (for a given time period) which IP addresses have failed so that those addresses are not repeatedly tried. The browser's "timeout" period is also selectively varied depending on the type of list returned from the name service.

Abstract: An apparatus and method for allocating virtual memory upon demand to reduce the amount of virtual memory allocated. Privilege level transitions requested by a program of instructions invoke a fault handler routine which allocates memory for implementing the transition. Allocation of memory is thus delayed until such request for privilege level transition occurs.