Patents by Inventor Charles Ryan Yates

Charles Ryan Yates has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SmartCore compositions and methods
    Patent number: 11752121
    Abstract: Nutritionally acceptable non-lipid compositions and methods are presented that modulate lipid metabolism, and especially increase LPC concentrations. Consequently, the compositions and methods presented herein will facilitate DHA transport to neural and retinal tissues as well as LA availability for cardiolipin synthesis.
    Type: Grant
    Filed: August 11, 2022
    Date of Patent: September 12, 2023
    Assignee: NPI, LLC
    Inventors: Charles Ryan Yates, Cameron Volpe Fili, Ling Lin, Jonathan Chapman, Hector L. Lopez
  • SmartCore Compositions and Methods
    Publication number: 20220378732
    Abstract: Nutritionally acceptable non-lipid compositions and methods are presented that modulate lipid metabolism, and especially increase LPC concentrations. Consequently, the compositions and methods presented herein will facilitate DHA transport to neural and retinal tissues as well as LA availability for cardiolipin synthesis.
    Type: Application
    Filed: August 11, 2022
    Publication date: December 1, 2022
    Applicant: NPI, LLC
    Inventors: Charles Ryan Yates, Cameron Volpe Fili, Ling Lin, Jonathan Chapman, Hector L. Lopez
  • Immunosuppressive compounds and therapeutics
    Patent number: 10369133
    Abstract: Here provided are new immunosuppressive compounds and novel therapeutics for improving tissue transplantation.
    Type: Grant
    Filed: July 23, 2014
    Date of Patent: August 6, 2019
    Assignee: THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION
    Inventors: Duane Douglas Miller, Charles Ryan Yates, Jayaprakash Pagadala, Ram Mahato, Hao Wu
  • Method for regulating retinal endothelial cell viability
    Patent number: 10010516
    Abstract: Here provided is a method for regulating retinal endothelial cell viability in a mammal by administering to the mammal a therapeutically effective amount of a quinic acid analog. The method may be applied to prevent, treat or cure pathological conditions of retinal endothelial cells associated with radiation retinopathy, diabetic retinopathy and chemotherapy for retinoblastoma.
    Type: Grant
    Filed: February 9, 2017
    Date of Patent: July 3, 2018
    Assignee: The University of Tennessee Research Foundation
    Inventors: Charles Ryan Yates, Jena Steinle Smith, Duane Douglas Miller, Jordan J. Toutounchian
  • Inhibitors of paxillin function and related compositions and methods
    Patent number: 9834525
    Abstract: This disclosure relates to small molecule inhibitors of paxillin and paxillin binding, and related compositions and methods of treatment.
    Type: Grant
    Filed: February 4, 2015
    Date of Patent: December 5, 2017
    Assignee: UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION
    Inventors: Charles Ryan Yates, Duane D. Miller, Frank Park, Jordan J. Toutounchian, Vanessa Morales-Tirado, Shivaputra Patil, Jayaprakash Pagadala, Bilal Abou Aleiwi
  • CRYSTALLINE SALTS OF (Z)-O-OCTADEC-9-EN-1-YL O,O-DIHYDROGEN PHOSPHOROTHIOATE
    Publication number: 20170226139
    Abstract: Here provided are a salt of Z)—O-octadec-9-en-1-yl O,O-dihydrogen phosphorothioate with an L-lysine addition in crystalline form and methods of making and using the same.
    Type: Application
    Filed: February 10, 2017
    Publication date: August 10, 2017
    Inventors: Rama Krishna Reddy Singidi, Veeresh Gududuru, Mahmoud Mirmehrabi, Karin Emmons Thompson, Gabor Jozsef Tigyi, Charles Ryan Yates, Jurriaan Strobos
  • Method for regulating retinal endothelial cell viability
    Patent number: 9566255
    Abstract: Here provided is a method for regulating retinal endothelial cell viability in a mammal by administering to the mammal a therapeutically effective amount of a quinic acid analog. The method may be applied to prevent, treat or cure pathological conditions of retinal endothelial cells associated with radiation retinopathy, diabetic retinopathy and chemotherapy for retinoblastoma.
    Type: Grant
    Filed: November 7, 2013
    Date of Patent: February 14, 2017
    Assignee: The University of Tennessee Research Foundation
    Inventors: Charles Ryan Yates, Jena Steinle Smith, Duane Douglas Miller, Jordan J. Toutounchian
  • Crystalline salts of (Z)-O-octadec-9-en-1-yl O,O-dihydrogen phosphorothioate
    Patent number: 9567288
    Abstract: Here provided are a salt of Z)—O-octadec-9-en-1-yl O,O-dihydrogen phosphorothioate with an L-lysine addition in crystalline form and methods of making and using the same.
    Type: Grant
    Filed: December 12, 2014
    Date of Patent: February 14, 2017
    Assignee: RxBio, Inc.
    Inventors: Rama Krishna Reddy Singidi, Veeresh Gududuru, Mahmoud Mirmehrabi, Karin Emmons Thompson, Gabor Jozsef Tigyi, Charles Ryan Yates, Jurriaan Strobos
  • INHIBITORS OF PAXILLIN FUNCTION AND RELATED COMPOSITIONS AND METHODS
    Publication number: 20160347725
    Abstract: This disclosure relates to small molecule inhibitors of paxillin and paxillin binding, and related compositions and methods of treatment.
    Type: Application
    Filed: February 4, 2015
    Publication date: December 1, 2016
    Inventors: Charles Ryan Yates, Duane D. Miller, Frank Park, Jordan J. Toutounchian, Vanessa Moraies-Tirado, Shivaputra Patil, Jayaprakash Pagadala, Bial Abou Aleiwi
  • IMMUNOSUPPRESSIVE COMPOUNDS AND THERAPEUTICS
    Publication number: 20160175281
    Abstract: Here provided are new immunosuppressive compounds and novel therapeutics for improving tissue transplantation.
    Type: Application
    Filed: July 23, 2014
    Publication date: June 23, 2016
    Inventors: Duane Douglas Miller, Charles Ryan Yates
  • Compounds with increased specificity for the treatment of glioma
    Patent number: 9187449
    Abstract: Disclosed are compounds for the treatment of cancer. Compounds disclosed herein are particularly effective for the selective inhibition of glioma cells.
    Type: Grant
    Filed: March 25, 2014
    Date of Patent: November 17, 2015
    Assignee: The University of Tennessee Research Foundation
    Inventors: Duane D. Miller, Shivaputra Appanna Patil, Renukadevi Patil, Terreia Jones, Amira Ahmed, Likeselam Asres, Charles Ryan Yates, Eldon Geisert
  • CRYSTALLINE SALTS OF (Z)-O-OCTADEC-9-EN-1-YL O,O-DIHYDROGEN PHOSPHOROTHIOATE
    Publication number: 20150183726
    Abstract: Here provided are a salt of Z)—O-octadec-9-en-1-yl O,O-dihydrogen phosphorothioate with an L-lysine addition in crystalline form and methods of making and using the same.
    Type: Application
    Filed: December 12, 2014
    Publication date: July 2, 2015
    Inventors: Rama Krishna Reddy Singidi, Veeresh Gududuru, Mahmoud Mirmehrabi, Karin Emmons Thompson, Gabor Jozsef Tigyi, Charles Ryan Yates, Jurriaan Strobos
  • Anti-inflammatory quinic acid derivatives for radioprotection/radiomitigation
    Patent number: 8906965
    Abstract: Disclosed are methods of use of analogs of quinic acids or shikimic acids for protection from the harmful effects of radiation when administered either prior to radiation exposure, after radiation exposure, or both. These methods are useful for treating humans and animals exposed to radiation and at risk for radiation sickness and/or death as the result of radiation exposure.
    Type: Grant
    Filed: May 11, 2010
    Date of Patent: December 9, 2014
    Assignee: The University of Tennessee Research Foundation
    Inventors: Charles Ryan Yates, Duane Douglas Miller, Mostafa Waleed Gaber, Karin Emmons Thompson, Kui Zeng, Jordan J. Toutounchian
  • COMPOUNDS WITH INCREASED SPECIFICITY FOR THE TREATMENT OF GLIOMA
    Publication number: 20140296286
    Abstract: Disclosed are compounds for the treatment of cancer. Compounds disclosed herein are particularly effective for the selective inhibition of glioma cells.
    Type: Application
    Filed: March 25, 2014
    Publication date: October 2, 2014
    Applicant: University of Tennessee Research Foundation
    Inventors: Duane D. Miller, Shivaputra Appanna Patil, Renukadevi Patil, Terreia Jones, Amira Ahmed, Likeselam Asres, Charles Ryan Yates, Eldon Geisert
  • METHOD FOR REGULATING RETINAL ENDOTHELIAL CELL VIABILITY
    Publication number: 20140094518
    Abstract: Here provided is a method for regulating retinal endothelial cell viability in a mammal by administering to the mammal a therapeutically effective amount of a quinic acid analog. The method may be applied to prevent, treat or cure pathological conditions of retinal endothelial cells associated with radiation retinopathy, diabetic retinopathy and chemotherapy for retinoblastoma.
    Type: Application
    Filed: November 7, 2013
    Publication date: April 3, 2014
    Applicant: The University of Tennessee Research Foundation
    Inventors: Charles Ryan Yates, Jena Steinle Smith, Duane Douglas Miller, Jordan J. Toutounchian
  • Therapeutic tetrahydroisoquinoline-based compositions for cancer therapy
    Patent number: 8507523
    Abstract: Disclosed are therapeutic tetrahydroisoquinoline compositions for the treatment of cancer, these compositions having selectivity for cancer cells while demonstrating few, if any, deleterious side effects on normal cells.
    Type: Grant
    Filed: November 21, 2007
    Date of Patent: August 13, 2013
    Inventors: Renukadevi Patil, Charles Ryan Yates, Duane D. Miller, Eldon E. Geisert
  • Anti-Inflammatory Quinic Acid Derivatives for Radioprotection/Radiomitigation
    Publication number: 20120283331
    Abstract: Disclosed are methods of use of analogs of quinic acids or shikimic acids for protection from the harmful effects of radiation when administered either prior to radiation exposure, after radiation exposure, or both. These methods are useful for treating humans and animals exposed to radiation and at risk for radiation sickness and/or death as the result of radiation exposure.
    Type: Application
    Filed: May 11, 2010
    Publication date: November 8, 2012
    Applicant: UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION
    Inventors: Charles Ryan Yates, Duane Douglas Miller, Mostafa Waleed Gaber, Karin Emmons Thompson, Kui Zeng, Jordan J. Toutounchian
  • 1,2,3,4-TETRAHYDROISOQUINOLINE DERIVATIVES EFFECTIVE AS ANTIGLIOMA AGENTS, METHODS OF MAKING, AND THEIR USE
    Publication number: 20120059032
    Abstract: Disclosed are tetrahydroisoquinoline-derivative compounds effective for killing cancer cells, shrinking tumor size, and treating cancer.
    Type: Application
    Filed: March 7, 2011
    Publication date: March 8, 2012
    Applicant: University of Tennessee Research Foundation
    Inventors: Renukadevi Patil, Shivaputra A. Patil, Duane D. Miller, Charles Ryan Yates, Eldon E. Geisert
  • Therapeutic Tetrahydroisoquinoline-Based Compositions for Cancer Therapy
    Publication number: 20080146597
    Abstract: Disclosed are therapeutic tetrahydroisoquinoline compositions for the treatment of cancer, these compositions having selectivity for cancer cells while demonstrating few, if any, deleterious side effects on normal cells.
    Type: Application
    Filed: November 21, 2007
    Publication date: June 19, 2008
    Applicant: UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION
    Inventors: Renukadevi Patil, Charles Ryan Yates, Duane D. Miller, Eldon E. Geisert