Patents by Inventor Charles S. Agree

Charles S. Agree has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fused pyrazole compounds, pharmaceutical compositions, and methods for modulating or inhibiting ERAB or HADH2 activity
    Patent number: 6964957
    Abstract: Pyrazole compounds represented by the formula: are described. The pyrazole compounds and pharmaceutical compositions containing them may be used in inhibiting ERAB or HADH2 activity and in treating ERAB, HADH2 or amyloid-? mediated diseases and conditions.
    Type: Grant
    Filed: August 17, 2001
    Date of Patent: November 15, 2005
    Assignee: Agouron Pharmaceuticals, Inc.
    Inventors: Melwyn A. Abreo, Jerry J. Meng, Charles S. Agree
  • Peptide mutant of human ERAB or HADH2, its X-ray crystal structure, and materials and method for identification of inhibitors thereof
    Publication number: 20020132319
    Abstract: The identification, isolation and modification of human ERAB or HADH2 is described. A crystal structure of ERAB or HADH2 is described which may be used in the discovery, identification and characterization of inhibitors or modulators of ERAB or HADH2. This structure provides a three-dimensional description of binding sites of ERAB or HADH2 for structure-based design of inhibitors or modulators thereof as therapeutic agents, for example in the treatment of Alzheimer's disease).
    Type: Application
    Filed: August 17, 2001
    Publication date: September 19, 2002
    Inventors: Melwyn A. Abreo, Charles S. Agree, Robert M. Aust, Charles R. Kissinger, Stephen Margosiak, Jerry J. Meng, Laura A. Pelletier, Paul Abraham Rejto, Richard Edward Showalter, James Arthur Thomson, Anna Tempczyk-Russell, Darin Vanderpool, Jesus Ernesto Villafranca
  • Pyrazole compounds, pharmaceutical compositions, and methods for modulating or inhibiting ERAB or HADH2 activity
    Publication number: 20020065292
    Abstract: Pyrazole compounds represented by the formula: 1
    Type: Application
    Filed: August 17, 2001
    Publication date: May 30, 2002
    Inventors: Melwyn A. Abreo, Jerry J. Meng, Charles S. Agree