Abstract: Apparatus and methods for culturing cells in a cell culture medium including magnetic beads in a fluid. A variable magnetic field can be applied to the magnetic beads to create shear forces on cells on the surface of the beads. In certain embodiments, a rotational force can also be applied to the magnetic beads and the magnetic force can counteract the rotational force.

Abstract: Devices and methods for extraction and processing of substantia gelatinea funiculi umbilicalis (Wharton's Jelly) from an umbilical cord.

Abstract: Devices and methods for extraction and processing of substantiagelatineafuniculi umbilicalis (Wharton's Jelly) from an umbilical cord.

Abstract: A bioreactor system for conditioning of pluripotent cells or cell media is provided. In further aspects, conditioned pluripotent cells and methods for making such cells are provided.

Abstract: Devices and methods for extraction and processing of substantiagelatineafuniculi umbilicalis (Wharton's Jelly) from an umbilical cord.

Abstract: A bioreactor system for conditioning of pluripotent cells or cell media is provided. In further aspects, conditioned pluripotent cells and methods for making such cells are provided.

Abstract: An apparatus for determining the capacity of a blood sample to clot, the apparatus having a body with a cavity thereon to receive the blood sample, a displacement member movably received on the body and movable from a first position to a second position, a spring element for imparting a retaining force against movement of the displacement member from the first position, and a discrete indicator for generating a signal when the displacement member is moved to the second position. The coagulation and contraction of the blood sample as it clots adheres to and moves the displacement member from the first position towards the second position against the retaining force of the spring element. The indicator may include a mechanical switch, an exothermic chemical switch, a chemiluminescent chemical switch, a segmented optical pathway, an electrical switch, a field effect transistor switch or a Hall effect magnetic switch.

Abstract: Devices and methods for extraction and processing of substantia gelatinea funiculi umbilicalis (Wharton's Jelly) from an umbilical cord. Isolated pluripotent cell compositions and methods of using the same are also provided.

Abstract: A bioreactor system for conditioning of pluripotent cells or cell media is provided. In further aspects, conditioned pluripotent cells and methods for making such cells are provided.

Abstract: A bioreactor system for conditioning of pluripotent cells or cell media is provided. In further aspects, conditioned pluripotent cells and methods for making such cells are provided.

Abstract: A bioreactor system for conditioning of potent cells or cell media is provided. In further aspects, conditioned pluripotent cells and methods for making such cells are provided.

Abstract: Devices and methods for extraction and processing of substantia gelatinea funiculi umbilicalis (Wharton's Jelly) from an umbilical cord. Isolated pluripotent cell compositions and methods of using the same are also provided.

Abstract: A portable body warming device comprised of a housing (1), a powered blower (19), a combustion chamber (25), an activator (27), a heat exchanger (35) within the housing, a portable hydrocarbon gas fuel source (39) and a battery for powering the blower and activator. The activator initiates combustion of fuel gas in the combustion chamber, and an exhaust vent port discharges combustion byproducts from the housing to serve as the portable warmer.

Abstract: The invention is directed to a multi-disk centrifugal pump suitable for pumping fluids, including biocompatible fluids, such as blood. The design of the pump components is optimized to reduce or eliminate the probability of clotting and hemolysis when pumping blood, and to be energy efficient and resistant to physical shock for portable applications.

Abstract: A device is provided for automatically inserting a catheter or other medical implement into a patient. An imaging module (100) identifies a selected point of insertion on the patient. A manipulator module (200) positions a catheter or medical implement at the desired position with respect to the selected point of insertion on the patient. A catheter insertion module (300) or implement insertion module (350) inserts the medical instrument into the patient to complete the desired tasks.

Abstract: A portable body warming device comprised of a housing (1), a powered blower (19), a combustion chamber (25), an activator (27), a heat exchanger (35) within the housing, a portable hydrocarbon gas fuel source (39) and a battery for powering the blower and activator. The activator initiates combustion of fuel gas in the combustion chamber, and an exhaust vent port discharges combustion byproducts from the housing to serve as the portable warmer.

Abstract: The invention provides methods for treating traumatic brain injury. The invention is generally directed to treating traumatic brain injury by administering cells that have one or more of the following effects in an injured subject: interact with splenocytes, preserve splenic mass, increase proliferation of CD4+ and CD8+ T-cells, increase IL-4 and IL-10, and increase M2:M1 macrophage ratio at the site of injury. The invention is also directed to drug discovery methods to screen for agents that modulate the ability of the cells to have these effects. The invention is also directed to cell banks that can be used to provide cells for administration to a subject, the banks comprising cells having desired potency for achieving these effects.

Abstract: The invention is directed to a multi-disk centrifugal pump suitable for pumping fluids, including biocompatible fluids, such as blood. The design of the pump components is optimized to reduce or eliminate the probability of clotting and hemolysis when pumping blood, and to be energy efficient and resistant to physical shock for portable applications.