Patents by Inventor Charles S. Hubscher

Charles S. Hubscher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of for improvement of lower urinary tract function
    Patent number: 11813446
    Abstract: The present invention relates to methods for improvement in lower urinary tract function in an individual with neurogenic urological dysfunction through epidural stimulation of the spinal cord. In certain embodiments, the methods comprise applying a pattern of epidural electrical stimulation to the spinal cord of an individual with impaired lower urinary tract under stimulation parameters sufficient to improve the storage of fluid in the bladder, sensations of fullness and/or emptying, detrusor over-activity, high detrusor pressure, voiding the bladder, transitioning from a storage state to a voiding state, and decreasing detrusor-external urethral sphincter dyssynergia. In certain embodiments, additional patterns of epidural electrical stimulation may be applied simultaneously, such as to maintain a normotensive cardiovascular state of the individual.
    Type: Grant
    Filed: April 4, 2020
    Date of Patent: November 14, 2023
    Assignee: University of Louisville Research Foundation, Inc.
    Inventors: Charles S. Hubscher, Susan J. Harkema, April N. Herrity, Yangsheng Chen, Claudia Angeli
  • METHODS OF FOR IMPROVEMENT OF LOWER URINARY TRACT FUNCTION
    Publication number: 20200316378
    Abstract: The present invention relates to methods for improvement in lower urinary tract function in an individual with neurogenic urological dysfunction through epidural stimulation of the spinal cord. In certain embodiments, the methods comprise applying a pattern of epidural electrical stimulation to the spinal cord of an individual with impaired lower urinary tract under stimulation parameters sufficient to improve the storage of fluid in the bladder, sensations of fullness and/or emptying, detrusor over-activity, high detrusor pressure, voiding the bladder, transitioning from a storage state to a voiding state, and decreasing detrusor-external urethral sphincter dyssynergia. In certain embodiments, additional patterns of epidural electrical stimulation may be applied simultaneously, such as to maintain a normotensive cardiovascular state of the individual.
    Type: Application
    Filed: April 4, 2020
    Publication date: October 8, 2020
    Applicant: University of Louisville Research Foundation, Inc.
    Inventors: Charles S. Hubscher, Susan J. Harkema, April N. Herrity, Yangsheng Chen, Claudia Angeli