Patents by Inventor Charles S. Markos

Charles S. Markos has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of 17.beta.-hydroxy-3-oxo-17.alpha.-pregn-4-ene-21-carboxylic acid .gamma.-lactone
    Patent number: 4057543
    Abstract: A new process utilizing certain novel intermediates for the preparation of 17.beta.-hydroxy-3-oxo-17.alpha.-pregn-4-ene-21-carboxylic acid .gamma.-lactone is described herein. The procedure utilizes readily available and inexpensive sarsasaponin as starting material.
    Type: Grant
    Filed: July 1, 1976
    Date of Patent: November 8, 1977
    Assignee: G. D. Searle & Co.
    Inventors: Hugh L. Dryden, Jr., Charles S. Markos
  • 2-[5-(CYCLIC AMINO) ETHYL-10,11-DIHYDRO-5H-dibenzo[a,d]-cyclohepten-5- yl]- 5
    Patent number: 4012393
    Abstract: This invention encompasses novel 2-[5-(cyclic amino)ethyl-10,11-dihydro-5H-dibenzo[a,d] cyclohepten-5-yl]-5-alkyl-1,3,4-oxadiazoles and congeners, useful as anti-diarrheal agents.
    Type: Grant
    Filed: March 22, 1976
    Date of Patent: March 15, 1977
    Assignee: G. D. Searle & Co.
    Inventors: Charles S. Markos, Chung H. Yen
  • (16.alpha.)-16,17-ALKYLIDENEBIS(OXY)-3-ARYLPREGNA-2,4-TRIEN-20-ONES
    Patent number: 3974143
    Abstract: Preparation of (16.alpha.)-16,17-alkylidenebis(oxy)-3-arylpregna-2,4,6-trien-20-ones and their progestational and glucocorticoid antiinflammatory utility are disclosed.
    Type: Grant
    Filed: September 19, 1975
    Date of Patent: August 10, 1976
    Assignee: G. D. Searle & Co.
    Inventor: Charles S. Markos