Patents by Inventor Charles Shoemaker
Charles Shoemaker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250066459Abstract: Provided are single-domain antibodies (sdAbs), also called heavy-chain-only variable domains (VHHs) or camelids, that contain reactive, non-canonical amino acids (ncAAs) and crosslink to target antigen protein. The target antigen may be a toxin or a neurotoxin produced by a pathogenic organism or microorganism that causes or is associated with a disease or pathology. Compositions and methods using the reactive ncAA-containing sdAbs to treat subjects afflicted with a pathology caused by a toxin- or neurotoxin-producing pathogen, such as Botulinum, are provided. In some cases, the compositions and methods comprising the sdAbs treat or prevent intoxication and inhibit and/or neutralize toxin or neurotoxin activity.Type: ApplicationFiled: November 11, 2024Publication date: February 27, 2025Applicant: Trustees of Tufts CollegeInventors: James Van Deventer, Charles Shoemaker, Rafael de Jesus Alcala-Torano
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Publication number: 20200206269Abstract: Multi-step methods for the in vitro production of enucleated red blood cells and the enucleated red blood cells thus prepared are provided. Such enucleated red blood cells may express fusion proteins comprising an antigen binding protein which allows the red blood cell to bind a toxin or an antigen of a pathogen. Also described herein are methods for neutralizing a toxin or pathogen in a subject by administering enucleated red blood cells that express any of the fusion proteins provided herein.Type: ApplicationFiled: August 22, 2018Publication date: July 2, 2020Applicants: Whitehead Institute for Biomedical Research, Trustees of Tufts CollegeInventors: Harvey Lodish, Nai-Jia Huang, Novalia Pishesha, Hidde L. Ploegh, Charles Shoemaker
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Patent number: 10275976Abstract: Methods, systems, and devices are disclosed for optimizing the delivery of products through an automated product dispensation system. The disclosed systems implement different dispensation parameters based on the size, shape, and other criteria for the different products that are dispensed through the device. The disclosed methods first identify the product being dispensed, and then determine the parameters at which the product should be dispensed for maximum efficiency.Type: GrantFiled: July 11, 2013Date of Patent: April 30, 2019Assignee: Freeosk, Inc.Inventors: Tony Lee Koenigsknecht, Albert John Kohn, Scott Alan Albright, Robert Kevin Blake, Jonathan Charles Shoemaker
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Patent number: 9446904Abstract: An interchangeable flighting insert is disclosed to maximize the efficiency of singularly delivering objects, such as products, to a user through a product dispensation device. The flighting insert can be removably coupled to an auger of the product dispensation device, thereby allowing variation of the flighting characteristics based on the object to be dispensed. The same auger can therefore use a first flighting for certain products, and a second flighting for different products.Type: GrantFiled: July 11, 2013Date of Patent: September 20, 2016Assignee: FREEOSK, INC.Inventors: Tony Lee Koenigsknecht, Albert John Kohn, Scott Alan Albright, Robert Kevin Blake, Jonathan Charles Shoemaker
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Publication number: 20130331979Abstract: An interchangeable flighting insert is disclosed to maximize the efficiency of singularly delivering objects, such as products, to a user through a product dispensation device. The flighting insert can be removably coupled to an auger of the product dispensation device, thereby allowing variation of the flighting characteristics based on the object to be dispensed. The same auger can therefore use a first flighting for certain products, and a second flighting for different products.Type: ApplicationFiled: July 11, 2013Publication date: December 12, 2013Applicant: Freeosk Marketing. Inc.Inventors: Tony Lee Koenigsknecht, Albert John Kohn, Scott Alan Albright, Robert Kevin Blake, Jonathan Charles Shoemaker
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Publication number: 20130331980Abstract: Methods, systems, and devices are disclosed for optimizing the delivery of products through an automated product dispensation system. The disclosed systems implement different dispensation parameters based on the size, shape, and other criteria for the different products that are dispensed through the device. The disclosed methods first identify the product being dispensed, and then determine the parameters at which the product should be dispensed for maximum efficiency.Type: ApplicationFiled: July 11, 2013Publication date: December 12, 2013Applicant: Freeosk Marketing, Inc.Inventors: Tony Lee Koenigsknecht, Albert John Kohn, Scott Alan Albright, Robert Kevin Blake, Jonathan Charles Shoemaker
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Publication number: 20060059572Abstract: Upon authentication via a required multi-function hardware component, coupled to a computer system with one or more computer-readable media, having a software product embodied thereon, one implementation, described herein, conditionally blocks or grants access to the software functionality of that software product on that computer system.Type: ApplicationFiled: September 10, 2004Publication date: March 16, 2006Applicant: Microsoft CorporationInventors: Charles Shoemaker, Colby Boles, John Elsbree, Mark Weinberg, Mark Newell, Michelle Niethammer, David Fulmer
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Publication number: 20050180978Abstract: The present invention relates to an isolated monoclonal antibody mAb PAB-1, deposited at ATCC on 24 Jan. 2002 and accorded accession PTA-4005, which binds to a surface antigen on nematode L3. It also relates to the antigen which binds to the monoclonal antibody and uses for the monoclonal antibody and antigen in diagnosing and treating or preventing nematode infection.Type: ApplicationFiled: January 30, 2003Publication date: August 18, 2005Applicants: OVITA LIMITED, AgResearch LimitedInventors: Gavin Harrison, Wayne Hein, Hugh Pulford, Charles Shoemaker
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Publication number: 20050080915Abstract: Systems and methods for providing a media device capabilities determination mechanism in a networked computing environment are provided. Some of today's operating systems and applications deliver a set of remoting features to enable a networked ecosystem of remote media consumption devices. These devices connect to the host and display a remoted media experience via remoting protocols and technologies. In this regard, the device capabilities determination mechanism of the invention enables a remote device to specify a custom set of media capabilities that should be remoted from the host to the remote device.Type: ApplicationFiled: September 30, 2003Publication date: April 14, 2005Inventors: Charles Shoemaker, Chia-Chi Teng, Hugh Vidos, Jay Gibson
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Patent number: 6227681Abstract: A floodlight fixture includes a base, a reflector assembly, an aiming mechanism coupled between the base and the reflector assembly, and a relamping mechanism coupled between the base and the reflector assembly. The aiming mechanism permits movement of the reflector assembly relative to the base to aim the reflector assembly and includes a locking mechanism used to fix a configuration of the aiming mechanism. The relamping mechanism permits movement of the reflector assembly between an aimed position and a relamping position without manipulating the locking mechanism to affect the configuration of the aiming mechanism.Type: GrantFiled: May 5, 1999Date of Patent: May 8, 2001Assignee: Cooper Technologies CompanyInventors: David Charles Shoemaker, Christopher Michael Bryant
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Patent number: 5974344Abstract: A wound care electrode including a flexible, electrically conductive body and an electrically conductive gel layer secured to the bottom of the electrically conductive body for releasably coupling the electrically conductive body with the skin of a user. A flexible, nonconductive, separating layer is secured to the top of the electrically conductive body. A flexible, absorbent dressing is secured to the top of the separating layer. The electrically conductive body, the electrically conductive gel layer, and the separating layer have axially aligned perforations for conveying seepage from the skin of a user to the absorbent dressing.Type: GrantFiled: March 2, 1998Date of Patent: October 26, 1999Inventor: Charles Shoemaker, II
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Patent number: D437441Type: GrantFiled: May 5, 1999Date of Patent: February 6, 2001Assignee: Cooper Technologies CompanyInventors: David Charles Shoemaker, Christopher Michael Bryant
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Patent number: D407996Type: GrantFiled: June 22, 1998Date of Patent: April 13, 1999Inventor: Charles Shoemaker, II