Abstract: Apparatuses, systems, and methods are provided for automatically selecting first and last frames for a sequence of frames from which an accumulation contrast image may be generated. In some examples, statistical distributions of groups of pixels of the image frames may be analyzed to generate parametric maps. The parametric maps may be analyzed to select the first and last image frames of the sequence. In some examples, an image frame corresponding to the parametric map having a value above a threshold value may be selected as a first frame. In some examples, an image frame corresponding to the parametric map having a maximum value of all the parametric maps may be selected as the last frame. In some examples, the parametric maps may be used to segment features, such as a tumor, from the image frame.

Abstract: An ultrasound system produces persisted images in response to both persistence coefficients and noise bias coefficients. The persistence coefficients control the degree of persistence, which reduces noise variance by persistence processing. The noise bias coefficients are produced in correspondence with the likelihood that an image pixel is noise, and operate to reduce the noise floor of the persisted images. A single user control enables a user to control both the noise variance and the noise level of images in tandem or, alternatively, dedicated controls can become available to adjust noise variance and noise level separately.

Abstract: Systems and methods for providing data for visualization and data for quantification are disclosed herein. The data for visualization may be used to generate images to provide to a user on a display. The data for quantification may be used to calculate various physiologically relevant parameters, such as hepato-renal index (HRI) values. In some examples, the quantification data may not be used to generate images. In some examples, a user may select regions of interest (ROIs) in the images generated from the visualization data and the corresponding quantification data for the ROIs may be used to calculate one or more parameters. The visualization data and quantification data may be generated from different imaging modes or same imaging modes with different data processing in some examples.

Abstract: A method for determining a physical characteristic on a punctual location inside a medium, comprising the steps of: sending an emitted sequence comprising emitted pulses having different amplitudes, receiving a received sequence comprising received pulses corresponding to echoes of emitted pulses, calculating a phase difference between the received pulses relative to the emitted pulses, and determining the physical characteristic on the bases of a phase difference.

Abstract: In some examples, color Doppler data may be separated into luminance data and chrominance data. The luminance data may be modified without modifying the chrominance data. In some examples, the luminance data may be adjusted based, at least in part, on power Doppler data. The adjusted luminance data may be recombined with the chrominance data to provide augmented color Doppler data. In some examples, the power Doppler data may be enhanced by filtering, for example, by applying a Frangi vesselness filter, prior to being used to adjust the luminance data of the color Doppler data.

Abstract: Systems and methods for multi-level vascular imaging for construction and display of vasculature from large to small vessels and micro-vessels using a combination of varying resolution contrast enhanced ultrasound flow imaging modalities are disclosed. While one or more resolution flow imaging modes may be employed for imaging large to small vessels of a vascular tree within a large region of interest, a high resolution mode, such as super resolution imaging, constructed for delineation of the microvascular morphology and directional microcirculation is provided within one or more small ROIs placed in selected locations within the larger ROI.

Abstract: Systems and methods for generating adaptive contrast accumulation imaging images are disclosed. A point spread function thinning/skeletonization technique may be performed on contrast enhanced image frames. An aggressiveness parameter of the technique may be adapted temporally and/or spatially. The aggressiveness parameter may be adapted based on various factors, including, but not limited to, time since injection of the contrast agent, signal intensity, and/or vessel size. The images may be temporally accumulated to generate a final sequence of adaptive contrast accumulation imaging images.

Abstract: Aspects of the present disclosure provide ultrasound systems and devices that provide for reduction of reverberation artifacts in ultrasound images by automatically changing imaging settings such as PRI or transmit/receive configuration based on detected amounts of reverberation in ultrasound images. In an exemplary embodiment, an apparatus includes a processor circuit in communication with an ultrasound probe. The processor circuit obtains a plurality of ultrasound images obtained using a plurality of different PRIs and/or pulse sequences, calculates an amount of reverberation artifacts in each of the plurality of ultrasound images, selects a pulse repetition interval and/or pulse sequence based on the amounts of reverberation artifacts in each of the plurality of ultrasound images, and controls the ultrasound transducer to obtain a reduced-reverberation ultrasound image using the selected pulse repetition interval or pulse sequence. The reduced-reverberation ultrasound image is then output to a display.

Abstract: Systems and methods for time-varying two-dimensional (2D) color maps for visualizing images or sequences of images are disclosed. The 2D color map may include brightness values of a hue corresponding to different intensities that changes over time. In some 2D color maps, the hue used for the intensity scale may change over time while the brightness of a pixel may not. In some 2D color maps, both the hue and the brightness may change relative to intensity over time.

Abstract: A particular sequence of ultrasound transmissions and corresponding echo receptions enables the production of Amplitude Modulated (AM) and Amplitude Modulated Phase Inverted (AMPI) signals that are temporally balanced. Temporal balancing significantly reduces tissue artifacts caused by movement of tissue during acquisition of the ultrasound echoes. Additionally, in combining the selected echo signals to produce the AM5 and AMPI signals, and optionally a Phase Inverted (PI) signal, each of the echo signals is equally weighted to facilitate an amplitude balance that avoids different echoes affecting the produced AM, AMPI, and PI signals differently.

Abstract: Systems and methods for preprocessing three dimensional (3D) data prior to generating inverted renders are disclosed herein. The preprocessing may include segmenting the 3D data to remove portions of the data associated with noise such that those portions do not appear in the generated render. The segmentation may include applying a mask to the 3D data. The mask may be generated by sorting data points in the 3D data set into a first set or a second set. In some examples, the 3D data may be filtered prior to generating the mask. In some examples, the mask may be adjusted based on feature recognition. The preprocessing may allow the visualization of hypoechoic regions of interest in a volume.

Abstract: Systems and methods for visualizing microbubbles for contrast-enhanced imaging are described herein. Microbubbles may be visualized by multi-pixel spots by identifying and localizing individual microbubbles. Motion compensation may be provided for localized microbubbles or for contrast images prior to microbubble identification and localization. Users may determine the size of the multi-pixel spot by adjusting a filter, for example, adjusting a threshold value of the filter. Altering the size of the multi-pixel spot may alter the resolution. As the number of pixels increases, the resolution decreases, but the acquisition time may also decrease. As the number of pixels decreases, the resolution increases, but the acquisition time may increase.

Abstract: The present disclosure describes ultrasound systems configured to perform microbubble-based contrast imaging with enhanced sensitivity. The systems can enhance echo signals derived from microbubbles while suppressing echo signals derived from tissue by detecting phase shifts exhibited by microbubbles in resonance. To detect the phase shifts, and thereby distinguish between microbubble-based signals and tissue-based signals, the systems can transmit a series of ultrasound pulses into a target region in accordance with a predefined sequence. The sequence can include an initiation pulse configured to stimulate microbubbles into nonlinear oscillation, a detection pulse configured to detect the nonlinear oscillation, and a summation pulse formed by transmitting an initiation pulse and detection pulse with a small time delay therebetween.

Abstract: A method for determining a physical characteristic on a punctual location inside a medium, comprising the steps of: sending an emitted sequence comprising emitted pulses having different amplitudes, receiving a received sequence comprising received pulses corresponding to echoes of said emitted pulses, calculating a phase difference between the received pulses relative to the emitted pulses, and determining the physical characteristic on the bases of said phase difference.

Abstract: An ultrasound system produces persisted images in response to both persistence coefficients and noise bias coefficients. The persistence coefficients control the degree of persistence, which reduces noise variance by persistence processing. The noise bias coefficients are produced in correspondence with the likelihood that an image pixel is noise, and operate to reduce the noise floor of the persisted images. A single user control enables a user to control both the noise variance and the noise level of images in tandem or, alternatively, dedicated controls can become available to adjust noise variance and noise level separately.

Abstract: A method for determining a physical characteristic on a punctual location inside a medium, comprising the steps of: sending an emitted sequence comprising emitted pulses having different amplitudes, receiving a received sequence comprising received pulses corresponding to echoes of said emitted pulses, calculating a phase difference between the received pulses relative to the emitted pulses, and determining the physical characteristic on the bases of said phase difference.