Abstract: The invention relates to a process employing a multi-directional heat pump and a cryo-trap to separate gases.

Abstract: An apparatus for containing and cooling enriched water for the production of activated fluorine (18F). A target assembly includes internal cooling channels in which developed flow of a coolant removes the heat from the target liquid in the target chamber. In one embodiment, the target assembly is fabricated of tantalum.

Abstract: A closure (10) for shielding, and selectively providing access to, the targeting assembly of a particle accelerator of a radioisotope production system. The closure (10) includes at least one, and in one embodiment, first and second doors (44, 46), for selectively covering an opening in the housing of the particle accelerator which provides access to the targeting assembly. A door mounting assembly is also provided for mounting the first and second doors (44, 46) on the housing of the particle accelerator. In one embodiment the door mounting assembly includes a frame (30) for being secured about the opening in the particle accelerator accessing the targeting assembly. Further, in one embodiment the frame (30) and first and second doors (44, 46) are fabricated of copper.

Abstract: A beta detector assembly for use in the synthesis and analysis of radiopharmaceuticals, such as in microfluidic radiochromatography. The beta detector assembly includes a base, preferably fabricated from glass so as to take advantage of electroosmotic flow, that serves as the body of the beta detector assembly. A microfluidic channel passes through the length of the base. A solid-state charge particle detector, for detecting beta particles, is provided and is positioned with respect to the base so as to receive beta particles. A portion of the base is disposed between the microfluidic channel and the solid-state charge particle detector and has a thickness that is selected to substantially allow transmission of beta particles there thru for detection by the charge particle detector. In one embodiment, the base is fabricated of glass. In another embodiment, the base is fabricated of silicon such that the base and the solid-state charge particle detector are integral.

Abstract: The invention provides a method and apparatus for preparation of radiochemicals wherein the reaction that couples the radioactive isotope to the reactive precursor to form a positron-emitting molecular imaging probe is performed in a microfluidic environment.