Abstract: An apparatus includes a substrate; a group III-Nitride barrier layer; a source electrically coupled to the group III-Nitride barrier layer; a gate on the group III-Nitride barrier layer; a drain electrically coupled to the group III-Nitride barrier layer; a p-region being arranged at or below the group III-Nitride barrier layer; and a recovery enhancement circuit configured to reduce an impact of an overload received by the gate. Additionally, at least a portion of the p-region is arranged vertically below at least one of the following: the source, the gate, an area between the gate and the drain.

Abstract: An apparatus includes a substrate; a group III-Nitride barrier layer; a source electrically coupled to the group III-Nitride barrier layer; a gate on the group III-Nitride barrier layer; a drain electrically coupled to the group III-Nitride barrier layer; a p-region being arranged at or below the group III-Nitride barrier layer; and a recovery enhancement circuit configured to reduce an impact of an overload received by the gate. Additionally, at least a portion of the p-region is arranged vertically below at least one of the following: the source, the gate, an area between the gate and the drain.

Abstract: The present invention, provides a method of treating cognitive impairment of Hunter syndrome. Among other things, the present invention provides a method comprising a step of administering intrathecally to a subject in need of treatment a recombinant iduronate-2-sulfatase (I2S) enzyme at a therapeutically effective dose and an administration interval for a treatment period sufficient to improve, stabilize or reduce declining of one or more cognitive, adaptive, motor, and/or executive functions relative to a control.

Abstract: The present invention, provides a method of treating cognitive impairment of Hunter syndrome.

Abstract: The present invention, provides a method of treating cognitive impairment of Hunter syndrome. Among other things, the present invention provides a method comprising a step of administering intrathecally to a subject in need of treatment a recombinant iduronate-2-sulfatase (I2S) enzyme at a therapeutically effective dose and an administration interval for a treatment period sufficient to improve, stabilize or reduce declining of one or more cognitive, adaptive, motor, and/or executive functions relative to a control.

Abstract: A solid-state lighting fixture includes a first group of solid-state light elements, a second group of solid-state light elements, and a light control module. The first group of solid-state light elements is configured to emit visible light at a first wavelength. The second group of solid-state light elements is configured to emit light at a second wavelength, which is different from the first wavelength. The light control module is configured to modulate the light emitted from the first group of solid-state light elements and modulate the light emitted from the second group of solid-state light elements, respectively, such that the modulation pattern of the emitted light from each one of the first group of solid-state light elements and the second group of solid-state light elements communicates a first subset of data and a second subset of data, respectively, while being undetectable to the human eye.

Abstract: a lighting fixture includes a power input configured to be coupled to a power source, a power output configured to be coupled to an external load and a lighting device, such as a light emitting diode (LED) device, coupled to the power input and configured to provide illumination. The lighting fixture further includes a protection circuit coupled between the power input and the power output and configured to detect a condition of a power source coupled to the power input and to control power transmission between the power input and the power output responsive to the detected condition. The power output may be configured to support daisy-chain connection of the lighting fixture to at least one other lighting fixture, and the protection circuit may be configured to control power transmission to the at least one other lighting fixture responsive to the detected condition.

Abstract: A system and method detect direction of movement. The system includes at least two radio frequency identification (RFID) readers arranged in different locations. The RFID readers transmit respective location signals from their locations and receive corresponding response signals from a portable electronic device (PED) when the PED is within range to receive the corresponding location signals, respectively. The system includes a controller configured to determine whether the individual response signals received by the RFID readers respectively satisfy a predetermined condition at a first time and a second time after the first time. The controller is configured to determine a direction of movement of the PED relative to the locations of the RFID readers during the first and second times based on whether the response signals respectively satisfy the predetermined condition at the first and second times, and control operations of the PED based on the determined movement of the PED.

Abstract: The present invention, provides a method of treating cognitive impairment of Hunter syndrome.

Abstract: A system and method are provided for detecting direction of movement. The system includes at least two radio frequency identification (RFID) readers arranged in different locations. The RFID readers transmit respective location signals from their locations and receive corresponding response signals from a portable electronic device (PED) when the PED is within range to receive the corresponding location signals, respectively. The system includes a controller configured to determine whether the individual response signals received by the RFID readers respectively satisfy a predetermined condition at a first time and a second time subsequent to the first time. The controller is also configured to determine a direction of movement of the portable electronic device relative to the locations of the RFID readers during the first and second times based on whether the response signals respectively satisfy the predetermined condition at the first and second times.

Abstract: The present invention provides a method of treating cognitive impairment of Hunter syndrome. Among other things, the present invention provides a method comprising a step of administering intrathecally to a subject in need of treatment a recombinant iduronate-2-sulfatase (I2S) enzyme at a therapeutically effective dose and an administration interval for a treatment period sufficient to improve, stabilize or reduce declining of one or more cognitive, adaptive, motor, and/or executive functions relative to a control.

Abstract: The present invention provides biomarkers for efficient and accurate characterization of Sanfilippo syndrome. In particular, the present invention provides biomarkers differentially expressed in Sanfilippo syndrome. Those biomarkers, used alone or in combination, may permit more accurate robust characterization of Sanfilippo syndrome, resulting in more precise determination of the types and/or severity of the syndrome. In addition, inventive biomarkers according to the present invention can be used to effective monitor treatment response in Sanfilippo syndrome patients and/or to optimize treatment for Sanfilippo syndrome.

Abstract: The present invention, provides a method of treating cognitive impairment of Hunter syndrome.

Abstract: A solid-state lighting fixture includes a first group of solid-state light elements, a second group of solid-state light elements, and a light control module. The first group of solid-state light elements is configured to emit visible light at a first wavelength. The second group of solid-state light elements is configured to emit light at a second wavelength, which is different from the first wavelength. The light control module is configured to modulate the light emitted from the first group of solid-state light elements and modulate the light emitted from the second group of solid-state light elements, respectively, such that the modulation pattern of the emitted light from each one of the first group of solid-state light elements and the second group of solid-state light elements communicates a first subset of data and a second subset of data, respectively, while being undetectable to the human eye.

Abstract: A lighting fixture includes a power input configured to be coupled to a power source, a power output configured to be coupled to an external load and a lighting device, such as a light emitting diode (LED) device, coupled to the power input and configured to provide illumination. The lighting fixture further includes a protection circuit coupled between the power input and the power output and configured to detect a condition of a power source coupled to the power input and to control power transmission between the power input and the power output responsive to the detected condition. The power output may be configured to support daisy-chain connection of the lighting fixture to at least one other lighting fixture, and the protection circuit may be configured to control power transmission to the at least one other lighting fixture responsive to the detected condition.

Abstract: The present disclosure presents a predictive signal producing method that effectively levels transmitter output power in a multi-carrier communication system and results in approaching amplifier performance normally associated with constant carrier waveforms. Embodiments of the disclosed solution offers >10 dB reduction in the peak-to-average power required to support the transmission of, for example, orthogonal frequency division modulation (“OFDM”) modulation techniques. Embodiments of the novel system and method maximize peak-to-average power ratio (“PAPR”) reduction with selective mapping and soft clipping, which may include filtering, combined. This novel approach also minimizes overhead, bit error rate, retransmissions, and increases latency as well as implementing processing cycles with a number of iterations.

Abstract: The present disclosure presents a predictive signal producing method that effectively levels transmitter output power in a multi-carrier communication system and results in approaching amplifier performance normally associated with constant carrier waveforms. Embodiments of the disclosed solution offers >10 dB reduction in the peak-to-average power required to support the transmission of, for example, orthogonal frequency division modulation (“OFDM”) modulation techniques. Embodiments of the novel system and method maximize peak-to-average power ratio (“PAPR”) reduction with selective mapping and soft clipping, which may include filtering, combined. This novel approach also minimizes overhead, bit error rate, retransmissions, and increases latency as well as implementing processing cycles with a number of iterations.

Abstract: The present disclosure presents a predictive signal producing method that effectively levels transmitter output power in a multi-carrier communication system and results in approaching amplifier performance normally associated with constant carrier waveforms. Embodiments of the disclosed solution offers >10 dB reduction in the peak-to-average power required to support the transmission of, for example, orthogonal frequency division modulation (“OFDM”) modulation techniques. Embodiments of the novel system and method maximize peak-to-average power ratio (“PAPR”) reduction with selective mapping and soft clipping, which may include filtering, combined. This novel approach also minimizes overhead, bit error rate, retransmissions, and increases latency as well as implementing processing cycles with a number of iterations.

Abstract: The present disclosure presents a predictive signal producing method that effectively levels transmitter output power in a multi-carrier communication system and results in approaching amplifier performance normally associated with constant carrier waveforms. Embodiments of the disclosed solution offers >10 dB reduction in the peak-to-average power required to support the transmission of, for example, orthogonal frequency division modulation (“OFDM”) modulation techniques. Embodiments of the novel system and method maximize peak-to-average power ratio (“PAPR”) reduction with selective mapping and soft clipping, which may include filtering, combined. This novel approach also minimizes overhead, bit error rate, retransmissions, and increases latency as well as implementing processing cycles with a number of iterations.

Abstract: The present disclosure presents a predictive signal producing method that effectively levels transmitter output power in a multi-carrier communication system and results in approaching amplifier performance normally associated with constant carrier waveforms. Embodiments of the disclosed solution offers >10 dB reduction in the peak-to-average power required to support the transmission of, for example, orthogonal frequency division modulation (“OFDM”) modulation techniques. Embodiments of the novel system and method maximize peak-to-average power ratio (“PAPR”) reduction with selective mapping and soft clipping, which may include filtering, combined. This novel approach also minimizes overhead, bit error rate, retransmissions, and increases latency as well as implementing processing cycles with a number of iterations.