Abstract: A system and method for the measurement of radiation emitted from an in-vivo administered radioactive analyte. Gamma radiation sensors may be used to determine the proper or improper administration of a radioactive analyte, and provide real time feedback to an autoinjector or other administration device or person. The feedback may include identification of an infiltration event and/or a likelihood that an infiltration event resulted in a radiation dose to a patient above a certain value, among other things.

Abstract: A system and method for the measurement of radiation emitted from an in-vivo administered radioactive analyte is presented. Gamma radiation sensors may be used to determine the proper or improper administration of a radioactive analyte. In some cases, the system utilizes computer program code executable by a computer processor that performs the steps of receiving signal data, accessing reference data, and comparing the signal data to the reference data to determine a likelihood of improper administration of the radioactive analyte to the subject.

Abstract: A system and method for the measurement of radiation emitted from an in-vivo administered radioactive analyte. Gamma radiation sensors may be used to determine the proper or improper administration of a radioactive analyte, and identify patient administration factors that correlate with improper administration over a set of patients so as to identify administration risk factors to improve administration of radioactive analyte. In some cases, the system employs a sensor having a scintillation material to convert gamma radiation to visible light, which enables embodiments of the sensor to be ex vivo. A light detector converts the visible light to an electrical signal. This signal is amplified and is processed to measure the captured radiation. The sensor enables collection of sufficient data to support separate application to predictive models, background comparisons, or change analysis.

Abstract: A system and method for the measurement of radiation emitted from an in-vivo administered radioactive analyte. Gamma radiation sensors may be used to determine the proper or improper administration of a radioactive analyte, and identify patient administration factors that correlate with improper administration over a set of patients so as to identify administration risk factors to improve administration of radioactive analyte. In some cases, the system employs a sensor having a scintillation material to convert gamma radiation to visible light, which enables embodiments of the sensor to be ex vivo. A light detector converts the visible light to an electrical signal. This signal is amplified and is processed to measure the captured radiation. The sensor enables collection of sufficient data to support separate application to predictive models, background comparisons, or change analysis.

Abstract: A system and method for the measurement of radiation emitted from an in-vivo administered radioactive analyte. Gamma radiation sensors may be used to determine the proper or improper administration of a radioactive analyte. In some cases, the system employs a sensor having a scintillation material to convert gamma radiation to visible light, which enables embodiments of the sensor to be ex vivo. A light detector converts the visible light to an electrical signal. This signal is amplified and is processed to measure the captured radiation. Temperature of the sensor may be recorded along with this radiation measurement for temperature compensation of ex vivo embodiments. The sensor enables collection of sufficient data to support separate application to predictive models, background comparisons, or change analysis.

Abstract: A system and method for the measurement of radiation emitted from an in-vivo administered radioactive analyte. Gamma radiation sensors may be used to determine the proper or improper administration of a radioactive analyte. In some cases, the system employs a sensor having a scintillation material to convert gamma radiation to visible light, which enables embodiments of the sensor to be ex vivo. A light detector converts the visible light to an electrical signal. This signal is amplified and is processed to measure the captured radiation. Temperature of the sensor may be recorded along with this radiation measurement for temperature compensation of ex vivo embodiments. The sensor enables collection of sufficient data to support separate application to predictive models, background comparisons, or change analysis.

Abstract: Various embodiments of a device for in-vivo measurements radiopharmaceuticals used for diagnosis and radiotherapy is presented. In some embodiments, the present disclosure relates to a scintillation device having a cannula that may include scintillation material and a delivery lumen, wherein the device may be used to both deliver material to the patient (e.g., deliver radiotracers used in radiopharmaceuticals) and measure levels of radioactive material in, for example, the patient's blood both during and after administration of the radioactive material. In some embodiments, particles emitted by the radioactive material interact with the scintillation material, resulting in the release of light that may be transmitted, via the scintillation material and/or fiber optic material, to one or more optical detectors or processors for processing.

Abstract: A system and method for the measurement of radiation emitted from an in-vivo administered radioactive analyte. Gamma radiation sensors may be used to determine the proper or improper administration of a radioactive analyte in some cases, the system employs a sensor having a scintillation material to convert gamma radiation to visible light, which enables embodiments of the sensor to be ex vivo. A light detector converts the visible light to an electrical signal. This signal is amplified and is processed to measure the captured radiation. Temperature of the sensor may be recorded along with this radiation measurement for temperature compensation of ex vivo embodiments. The sensor enables collection of sufficient data to support separate application to predictive models, background comparisons, or change analysis.

Abstract: Oncology monitoring systems include: (a) a first plurality of radiation sensors configured to reside proximate a target tumor treatment site of a patient, the sensors being configured to provide radiation data associated with the tumor treatment site; and (b) a first portable receiver in communication with the plurality of sensors. The receiver is configured to obtain radiation data from the sensors at a plurality of different times. The receiver is in communication with a local and/or remote computer that tracks variation in the radiation data to provide dynamic tumor site information.

Abstract: A system and method for the measurement of radiation emitted from an in-vivo administered radioactive analyte. Gamma radiation sensors may be used to determine the proper or improper administration of a radioactive analyte in some cases, the system employs a sensor having a scintillation material to convert gamma radiation to visible light, which enables embodiments of the sensor to be ex vivo. A light detector converts the visible light to an electrical signal. This signal is amplified and is processed to measure the captured radiation. Temperature of the sensor may be recorded along with this radiation measurement for temperature compensation of ex vivo embodiments. The sensor enables collection of sufficient data to support separate application to predictive models, background comparisons, or change analysis.

Abstract: A system and method for the measurement of radiation emitted from an in-vivo administered radioactive analyte. Gamma radiation sensors may be used to determine the proper or improper administration of a radioactive analyte in some cases, the system employs a sensor having a scintillation material to convert gamma radiation to visible light, which enables embodiments of the sensor to be ex vivo. A light detector converts the visible light to an electrical signal. This signal is amplified and is processed to measure the captured radiation. Temperature of the sensor may be recorded along with this radiation measurement for temperature compensation of ex vivo embodiments. The sensor enables collection of sufficient data to support separate application to predictive models, background comparisons, or change analysis.

Abstract: A system for the measurement of radiation emitted from an in-vivo administered radioactive analyte. The system employs a sensor having a scintillation material to convert gamma radiation to visible light, which enables embodiments of the sensor to be ex vivo. A light detector converts the visible light to an electrical signal. This signal is amplified and is processed to measure the captured radiation. Temperature of the sensor may be recorded along with this radiation measurement for temperature compensation of ex vivo embodiments. The sensor enables collection of sufficient data to support separate application to predictive models, background comparisons, or change analysis.

Abstract: A system for the measurement of radiation emitted from an in-vivo administered radioactive analyte. The system employs a sensor having a scintillation material to convert gamma radiation to visible light, which enables embodiments of the sensor to be ex vivo. A light detector converts the visible light to an electrical signal. This signal is amplified and is processed to measure the captured radiation. Temperature of the sensor may be recorded along with this radiation measurement for temperature compensation of ex vivo embodiments. The sensor enables collection of sufficient data to support separate application to predictive models, background comparisons, or change analysis.

Abstract: Biocompatible sensors configured for implantation include a first body in communication with a plurality of remote sensor bodies to detect physiological parameters in vivo.

Abstract: Oncology monitoring systems include: (a) a first plurality of radiation sensors configured to reside proximate a target tumor treatment site of a patient, the sensors being configured to provide radiation data associated with the tumor treatment site; and (b) a first portable receiver in communication with the plurality of sensors. The receiver is configured to obtain radiation data from the sensors at a plurality of different times. The receiver is in communication with a local and/or remote computer that tracks variation in the radiation data to provide dynamic tumor site information.

Abstract: Biocompatible sensors configured for implantation include a first body in communication with a plurality of remote sensor bodies to detect physiological parameters in vivo.

Abstract: Methods and systems for evaluating external beam radiation therapy delivered to a subject include: (a) placing at least one wireless implantable sensor in a first subject at a target location; (b) administering a first dose of radiation therapy into the first subject; (c) obtaining radiation data from the at least one wireless implantable sensor; and (d) calculating a radiation dose amount received by the first subject at the target location based on the radiation data obtained from the at least one wireless sensor during and/or after exposure to the first administered dose of radiation to determine and/or verify a dose amount of radiation delivered to the target location.

Abstract: Methods and systems for evaluating external beam radiation therapy delivered to a subject include: (a) placing at least one wireless implantable sensor in a first subject at a target location; (b) administering a first dose of radiation therapy into the first subject; (c) obtaining radiation data from the at least one wireless implantable sensor; and (d) calculating a radiation dose amount received by the first subject at the target location based on the radiation data obtained from the at least one wireless sensor during and/or after exposure to the first administered dose of radiation to determine and/or verify a dose amount of radiation delivered to the target location.

Abstract: Methods and systems for evaluating external beam radiation therapy delivered to a subject include: (a) placing at least one wireless implantable sensor in a first subject at a target location; (b) administering a first dose of radiation therapy into tile first subject; (c) obtaining radiation data from the at least one wireless implantable sensor; and (d) calculating a radiation dose amount received by the first subject at the target location based on the radiation data obtained from the at least one wireless sensor during and/or after exposure to the first administered dose of radiation to determine and/or verify a dose amount of radiation delivered to the target location.

Abstract: Biocompatible sensors configured for implantation include a first body in communication with a plurality of remote sensor bodies to detect physiological parameters in vivo.