Abstract: Methods and systems providing for collaborative commenting in a drawing tool are provided. One example method includes receiving a shape on a drawing canvas, and receiving a comment associated with the shape, the comment including a name of a commenting user. The method also includes receiving an indication of a movement of the shape from the first position to a second position, and, in response to the indication of the movement of the shape, automatically moving the comment closer to the second position of the shape. In some cases, the commenting user can be a user other than the user adding the shape to the document, and can be performed by a concurrent editor of the document.

Abstract: Integrated workflow visualization and editing is provided using a visual graphic diagramming tool and a web application platform tool to create a workflow. A visual representation of a workflow is created using the visual graphic diagramming tool. A declarative markup language file representing the workflow is provided to a web application platform tool for further modification of the workflow. The workflow is opened in the web application platform tool and desired parameters in the workflow are set. Visualization data from the graphic diagramming tool and the set parameters are bundled in a single declarative markup language file formatted for reading by both the visual graphic diagramming tool and the web application platform tool to allow manipulations and parameterization of the workflow in both the visual graphic diagramming tool and the web application platform tool.

Abstract: Integrated workflow visualization and editing is provided using a visual graphic diagramming tool and a web application platform tool to create a workflow. A visual representation of a workflow is created using the visual graphic diagramming tool. A declarative markup language file representing the workflow is provided to a web application platform tool for further modification of the workflow. The workflow is opened in the web application platform tool and desired parameters in the workflow are set. Visualization data from the graphic diagramming tool and the set parameters are bundled in a single declarative markup language file formatted for reading by both the visual graphic diagramming tool and the web application platform tool to allow manipulations and parameterization of the workflow in both the visual graphic diagramming tool and the web application platform tool.

Abstract: Methods and systems providing for collaborative commenting in a drawing tool are provided. One example method includes receiving a shape on a drawing canvas, and receiving a comment associated with the shape, the comment including a name of a commenting user. The method also includes receiving an indication of a movement of the shape from the first position to a second position, and, in response to the indication of the movement of the shape, automatically moving the comment closer to the second position of the shape. In some cases, the commenting user can be a user other than the user adding the shape to the document, and can be performed by a concurrent editor of the document.

Abstract: The present invention relates to novel adenovirus vectors for use in gene therapy which are designed to prevent the generation of replication-competent adenovirus (RCA) during in vitro propagation and clinical use. The invention also provides methods for the production of the novel virus vectors. These vectors maximize safety for clinical applications in which adenovirus vectors are used to transfer genes into recipient cells for gene therapy.

Abstract: The present invention relates to novel adenovirus vectors for use in gene therapy which are designed to prevent the generation of replication-competent adenovirus (RCA) during in vitro propagation and clinical use. The invention also provides methods for the production of the novel virus vectors. These vectors maximize safety for clinical applications in which adenovirus vectors are used to transfer genes into recipient cells for gene therapy.

Abstract: Disclosed is a crane wherein a trailer-like counterweight carrier has a horizontal motion transmitting connection with a platform which is swivelably mounted on a crane base and which supports the boom and the mast of the crane. Guy connections between the counterweight carrier and the top of the mast and between the mast and the boom translate forward tilting force that a lifted load imposes upon the boom into lifting force on the counterweight carrier. A lost motion connection between the counterweight carrier and the platform comprises rigid members. It allows the carrier to be lifted to a predetermined height above the ground and at that point imposes upon the crane chassis further lift force upon the counterweight carrier, so that the crane base cooperates with the counterweight in resisting forward tilting of the boom under heavy loads. The lost motion connection requires no adjustment to adapt it for different loads and different inclinations of the boom and mast.

Abstract: A method and system for a rapid and sensitive method for determining immunologically active materials in a biological fluid by observing an antigen-antibody reaction after application of reactants on the surface of a gel matrix and applying an alternating current thereto.