Patents by Inventor Charles Waechter

Charles Waechter has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biosynthetic system that produces immunogenic polysaccharides in prokaryotic cells
    Patent number: 9764018
    Abstract: The invention is directed to bioconjugate vaccines comprising N-glycosylated proteins. Further, the present invention is directed to a recombinant prokaryotic biosynthetic system comprising nucleic acids encoding an epimerase that synthesizes an oligo- or polysaccharide having N-acetylgalactosamine at the reducing terminus. The invention is further directed to N-glycosylated proteins containing an oligo- or polysaccharide having N-acetylgalactosamine at the reducing terminus and an expression system and methods for producing such N-glycosylated proteins.
    Type: Grant
    Filed: August 18, 2014
    Date of Patent: September 19, 2017
    Assignee: GLYCOVAXYN AG
    Inventors: Michael Wacker, Charles Waechter
  • BIOSYNTHETIC SYSTEM THAT PRODUCES IMMUNOGENIC POLYSACCHARIDES IN PROKARYOTIC CELLS
    Publication number: 20150190492
    Abstract: The invention is directed to bioconjugate vaccines comprising N-glycosylated proteins. Further, the present invention is directed to a recombinant prokaryotic biosynthetic system comprising nucleic acids encoding an epimerase that synthesizes an oligo- or polysaccharide having N-acetylgalactosamine at the reducing terminus. The invention is further directed to N-glycosylated proteins containing an oligo- or polysaccharide having N-acetylgalactosamine at the reducing terminus and an expression system and methods for producing such N-glycosylated proteins.
    Type: Application
    Filed: August 18, 2014
    Publication date: July 9, 2015
    Applicant: GlycoVaxyn AG
    Inventors: Michael Wacker, Charles Waechter
  • Biosynthetic system that produces immunogenic polysaccharides in prokaryotic cells
    Patent number: 8846342
    Abstract: The invention is directed to bioconjugate vaccines comprising N-glycosylated proteins. Further, the present invention is directed to a recombinant prokaryotic biosynthetic system comprising nucleic acids encoding an epimerase that synthesizes an oligo- or polysaccharide having N-acetylgalactosamine at the reducing terminus. The invention is further directed to N-glycosylated proteins containing an oligo- or polysaccharide having N-acetylgalactosamine at the reducing terminus and an expression system and methods for producing such N-glycosylated proteins.
    Type: Grant
    Filed: November 16, 2010
    Date of Patent: September 30, 2014
    Assignee: GlycoVaxyn AG
    Inventors: Michael Wacker, Charles Waechter
  • BIOSYNTHETIC SYSTEM THAT PRODUCES IMMUNOGENIC POLYSACCHARIDES IN PROKARYOTIC CELLS
    Publication number: 20130028926
    Abstract: The invention is directed to bioconjugate vaccines comprising N-glycosylated proteins. Further, the present invention is directed to a recombinant prokaryotic biosynthetic system comprising nucleic acids encoding an epimerase that synthesizes an oligo- or polysaccharide having N-acetylgalactosamine at the reducing terminus. The invention is further directed to N-glycosylated proteins containing an oligo- or polysaccharide having N-acetylgalactosamine at the reducing terminus and an expression system and methods for producing such N-glycosylated proteins.
    Type: Application
    Filed: November 16, 2010
    Publication date: January 31, 2013
    Applicant: GLYCOVAXYN AG
    Inventors: Michael Wacker, Charles Waechter