Abstract: The disclosed 2-D resistance tomographic imaging method optimizes computation speed for performing electrical impedance tomography using a model-space with a minimal number of orthonormal polynomial basis functions to describe discernable features in the 2-D resistance tomographic image, determining a minimal number of contacts to take fewer measurements than available information based on the number of basis functions, selecting a subset of rows of a matrix of calculated sensitivity coefficients to form a square Jacobian matrix for a linearized forward problem to be solved and inversion of the linear forward problem, and solving an inverse problem based on the square Jacobian matrix by performing at least one iteration of a Newton's method solve.

Abstract: The present disclosure provides binding proteins (e.g., antibodies or antigen binding fragments thereof) that specifically bind to Klebsiella pneumoniae O2 and induce opsonophagocytic killing of Klebsiella (e.g., Klebsiella pneumoniae) and/or protects mice from a lethal Klebsiella challenge. The present disclosure also provides methods of reducing Klebsiella (e.g., Klebsiella pneumoniae) or treating or preventing Klebsiella (e.g., Klebsiella pneumoniae) infection in a subject comprising administering the Klebsiella pneumoniae O2 binding proteins, (e.g., antibodies or antigen-binding fragments thereof) to the subject.

Abstract: The present disclosure describes various aspects of remote presence interfaces (RPIs) for use on portable electronic devices (PEDs) to interface with remote presence devices. An RPI may allow a user to interact with a telepresence device, view a live video feed, provide navigational instructions, and/or otherwise interact with the telepresence device. The RPI may allow a user to manually, semi-autonomously, or autonomously control the movement of the telepresence device. One or more panels associated with a video feed, patient data, calendars, date, time, telemetry data, PED data, telepresence device data, healthcare facility information, healthcare practitioner information, menu tabs, settings controls, and/or other features may be utilized via the RPI.

Abstract: The present application discloses stretched films comprising regioselectively substituted cellulose esters and a component A: (I), (II), (III), or (IV), wherein A, B, C, R1, R2, R5, R6, R8, R9, m, n, and k are defined herein. The films exhibit negative birefringence and improved wavelength dispersion.

Abstract: A measuring assembly for a measuring tape device may include a blade, an end hook and an anti-rollover attachment. The blade may include a first end configured to extend from an aperture in a housing of the measuring tape device and a second end configured to be wound on a reel assembly. The end hook may be disposed at the first end of the blade to engage an object for measurement, and may extend substantially perpendicular to a longitudinal centerline of the blade to extend away from an underside of the blade. The anti-rollover attachment may be disposed proximate to the end hook at the first end of the blade such that a center of gravity of the anti-rollover attachment is spaced apart from the underside of the blade. A combined weight of the end hook and the anti-rollover attachment may be in a range between about 10 grams and about 55 grams.

Abstract: A hand tool includes an elongate, plate shaped steel core having a top face and a bottom face in parallel planes, a drive head portion formed at one end of the steel core and having a drive head cavity formed therein, a tang portion extending from the drive head portion to the other end of the steel core, a ratchet assembly disposed in the drive head cavity, and a first encapsulation layer covering the tang portion and the drive head portion, but not covering at least a portion of the ratchet assembly. The first encapsulation layer may include a fiber reinforced plastic composite material.

Abstract: Techniques for identifying a root cause of an operational result of a deterministic machine learning model are disclosed. A system applies a deterministic machine learning model to a set of data to generate an operational result, such as a prediction of a “fault” or “no-fault” in the system. The set of data includes signals from multiple different data sources, such as sensors. The system applies an abductive model, generated based on the deterministic machine learning model, to the operational result. The abductive model identifies a particular set of data sources that is associated with the root cause of the operational result. The system generates a human-understandable explanation for the operational result based on the identified root cause.

Abstract: A robotic vacuum cleaner may include a housing, a displaceable bumper, an emitter/detector pair, and at least one divider. The displaceable bumper may be moveably coupled to the housing and may be configured to be displaced along at least one axis. The emitter/detector pair may have an emitter and a detector, wherein the emitter is configured to emit light through at least a portion of the displaceable bumper. The at least one divider may be disposed between the emitter and the detector of the emitter/detector pair.

Abstract: Various embodiments may provide streaming service downlink assistance and/or uplink assistance mechanisms for a wireless device using attention (AT) commands exchanged between a modem processor of the wireless device and another processor of the wireless device. Various embodiments may include an AT command that is a bitrate recommendation action command including an indication of a stream identifier, an indication of a requested bitrate, and an indication of a direction. Various embodiments may include an AT response that is a bitrate recommendation response, the bitrate recommendation response including an indication of a stream identifier, an indication of a bitrate recommendation, and an indication of a direction.

Abstract: The invention provides compounds of Formula (I) as described herein, along with pharmaceutically acceptable salts, pharmaceutical compositions containing such compounds, and methods to use these compounds, salts and compositions for treating viral infections, particularly infections caused by herpesviruses.

Abstract: The subject matter of this specification can be implemented in, among other things, a method, system, and/or device to receive current metrology data for an operation on a current sample in a fabrication process. The metrology data includes a current value for a parameter at each of one or more locations on the current sample. The method further includes determining a current rate of change of the parameter value for each of the one or more locations. The current rate of change is associated with the current sample. The method further includes identifying one or more violating locations each having an associated current rate of change of the parameter value that is greater than an associated reference rate of change of the parameter value, and identifying an instance of abnormality of the fabrication process based on the one or more violating locations.

Abstract: An optical fiber configured to improve the pump conversion efficiency of an L-band fiber amplifier which uses the multimode pump source. By directly absorbing multimode light including 915 nm, an active fiber core region co-doped with both erbium and ytterbium can provide gain to the L-band signals via stimulated emission. The unwanted C-band amplified spontaneous emission (ASE) light generate from this active fiber core region can be absorbed by another active fiber core region doped with erbium, then provides additional gain to the L-band signals. Active regions and cladding can be configured to match a given spatial mode of the optical signal. Signal-pump combiners with end-coupling or side coupling can be used.

Abstract: The present invention provides a prosthetic heart valve device that has a frame, and a leaflet assembly having a plurality of leaflets that are secured to the frame. The frame is defined by an annular body and has three spaced-apart commissure regions, each commissure region having a commissure post extending from a proximal outflow end of the frame. A first clipping arm and a second clipping arm extend from opposite sides of each commissure post, each clipping arm extending from each commissure post at an obtuse angle with respect to each commissure post. Each clipping arm has a free end with a tip provided at the free end. The body has a first diameter at a location where the tips of the clipping arms are located, and the tips of the clipping arms extend away from define a second diameter, with the second diameter being greater than or equal to the first diameter.

Abstract: A processor coupled to memory is configured to receive an identification of a geographical location associated with a target specified by a user remote from a vehicle. A machine learning model is utilized to generate a representation of at least a portion of an environment surrounding the vehicle using sensor data from one or more sensors of the vehicle. At least a portion of a path to a target location corresponding to the received geographical location is calculated using the generated representation of the at least portion of the environment surrounding the vehicle. At least one command is provided to automatically navigate the vehicle based on the determined path and updated sensor data from at least a portion of the one or more sensors of the vehicle.

Abstract: Provided herein are compounds according to Formula (I) or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R5, and R7 are defined herein. Also provided herein are pharmaceutical compositions comprising a compound of Formula (I) as well as the use of such compounds as M4 receptor agonists.

Abstract: Systems and methods for multi-level vascular imaging for construction and display of vasculature from large to small vessels and micro-vessels using a combination of varying resolution contrast enhanced ultrasound flow imaging modalities are disclosed. While one or more resolution flow imaging modes may be employed for imaging large to small vessels of a vascular tree within a large region of interest, a high resolution mode, such as super resolution imaging, constructed for delineation of the microvascular morphology and directional microcirculation is provided within one or more small ROIs placed in selected locations within the larger ROI.

Abstract: Various embodiments described herein illustrate a glove that includes an anterior portion and a posterior portion. The anterior portion is knitted seamlessly with the posterior portion to define a metacarpal region and a plurality of finger regions extending out from the metacarpal region. A first conductive pad is knitted on the anterior portion of the glove. The first conductive pad is knitted on a distal end portion of a first finger region. A second conductive pad knitted on the posterior portion of the glove. Further, the second conductive pad is knitted on a second finger region. An electronic device is removably attached to the posterior portion and is in electrical communication with the first conductive pad and the second conductive pad. The electronic device is triggered in an instance in which the first conductive pad contacts the second conductive pad.

Abstract: Systems and methods for generating adaptive contrast accumulation imaging images are disclosed. A point spread function thinning/skeletonization technique may be performed on contrast enhanced image frames. An aggressiveness parameter of the technique may be adapted temporally and/or spatially. The aggressiveness parameter may be adapted based on various factors, including, but not limited to, time since injection of the contrast agent, signal intensity, and/or vessel size. The images may be temporally accumulated to generate a final sequence of adaptive contrast accumulation imaging images.

Abstract: Provided herein are compounds according to Formula (I) or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R5, and R7 are defined herein. Also provided herein are pharmaceutical compositions comprising a compound of Formula (I) as well as the use of such compounds as M4 receptor agonists.

Abstract: In an example, a method includes collecting biodata of a subject. The method includes generating or updating a personalized ML model of the subject from the biodata of the subject. The method includes detecting anomalies in the biodata based on the personalized ML model. The method includes filtering the detected anomalies to determine whether the detected anomalies indicate that the subject has a clinical condition or is at risk of having the clinical condition.