Abstract: The invention provides certain difluorocyclohexyl-imidazopyridazinyl-imidazolidinone compounds of formula II as IL-17A inhibitors, pharmaceutical compositions thereof, and methods of using a compound of formula II to treat certain symptoms of psoriasis, rheumatoid arthritis or multiple sclerosis.

Abstract: The present invention provides novel ROR gamma-t inhibitors and pharmaceutical compositions thereof, formula (A).

Abstract: An improved hollow point bullet has a core of a soft, dense metal having a generally cylindrical rear section, a tapering front section, and an open forward end opening to a cavity. A jacket of a harder metal than the core surrounds at least the rear and front sections of the core, and extends at least partially into the cavity. An expander of a rigid polymer is disposed in the cavity, substantially filling the cavity and providing at least one passage through to the bottom of the cavity.

Abstract: An improved hollow point bullet has a core of a soft, dense metal having a generally cylindrical rear section, a tapering front section, and an open forward end opening to a cavity. A jacket of a harder metal than the core surrounds at least the rear and front sections of the core, and extends at least partially into the cavity. An expander of a rigid polymer is disposed in the cavity, substantially filling the cavity and providing at least one passage through to the bottom of the cavity.

Abstract: The present invention provides novel ROR gamma-t inhibitors and pharmaceutical compositions thereof. Formula (I).

Abstract: The present invention provides novel ROR gamma-t inhibitors and pharmaceutical compositions thereof, formula (A).

Abstract: An electrically-controlled water flow regulator for use with a poultry watering system receives potable water at a first, high flow rate and reduces the water flow rate of the water provided to watering valves that dispense water to the flock within a poultry house. A variable control valve uses a needle-shaped cone to engage a mating port inside the housing of the regulator. A motor controls the linear movement of the control valve in incremental steps to adjust the water flow rate provided to the flock. A feedback component enables the variable control valve to maintain the water flow rate at a desired set point for the flock. The desired set point for the flock is controlled or automated to match the growth of the flock over their growth cycle. An electrical controller and suitable cabling enable multiple regulators to be controlled efficiently and cost-effectively.

Abstract: The present invention provides novel ROR gamma-t inhibitors and pharmaceutical compositions thereof. Formula (I).

Abstract: An electrically-controlled water flow regulator for use with a poultry watering system receives potable water at a first, high flow rate and reduces the water flow rate of the water provided to watering valves that dispense water to the flock within a poultry house. A variable control valve uses a needle-shaped cone to engage a mating port inside the housing of the regulator. A motor controls the linear movement of the control valve in incremental steps to adjust the water flow rate provided to the flock. A feedback component enables the variable control valve to maintain the water flow rate at a desired set point for the flock. The desired set point for the flock is controlled or automated to match the growth of the flock over their growth cycle. An electrical controller and suitable cabling enable multiple regulators to be controlled efficiently and cost-effectively.

Abstract: An improved, self-balancing water distribution system uses siphon characteristics to maintain negative pressure within the water system and to enable distribution of water to one or more distribution points, such as drinker lines with drinker nipples, at a controlled pressure, for consumption by poultry. The system includes water conduit connected to and configured to distribute water from a water supply reservoir to the one or more distribution points. The water level of the water supply reservoir is used to control the water pressure within the system. A vacuum apparatus is connected to the water conduit to remove entrapped air within the system to help maintain negative pressure within the conduit and throughout the system.

Abstract: An electrically-controlled water flow regulator for use with a poultry watering system receives potable water at a first, high flow rate and reduces the water flow rate of the water provided to watering valves that dispense water to the flock within a poultry house. A variable control valve uses a needle-shaped cone to engage a mating port inside the housing of the regulator. A motor controls the linear movement of the control valve in incremental steps to adjust the water flow rate provided to the flock. A feedback component enables the variable control valve to maintain the water flow rate at a desired set point for the flock. The desired set point for the flock is controlled or automated to match the growth of the flock over their growth cycle. An electrical controller and suitable cabling enable multiple regulators to be controlled efficiently and cost-effectively.

Abstract: An improved, self-balancing water distribution system uses siphon characteristics to maintain negative pressure within the water system and to enable distribution of water to one or more distribution points, such as drinker lines with drinker nipples, at a controlled pressure, for consumption by poultry. The system includes water conduit connected to and configured to distribute water from a water supply reservoir to the one or more distribution points. The water level of the water supply reservoir is used to control the water pressure within the system. A vacuum apparatus is connected to the water conduit to remove entrapped air within the system to help maintain negative pressure within the conduit and throughout the system.

Abstract: Methods, systems, and apparatuses for creating collections of associated accounts for a migration process. An example system includes a processing device and memory that stores accounts in accordance with at least one domain. The processing device may create a collection of related accounts stored in accordance with the at least one domain based on active directory information of the stored accounts and information gathered from a survey and may migrate information included in the at least one domain.

Abstract: Methods, systems, and apparatuses for creating collections of associated accounts for a migration process. An example system includes a processing device and memory that stores accounts in accordance with at least one domain. The processing device may create a collection of related accounts stored in accordance with the at least one domain based on active directory information of the stored accounts and information gathered from a survey and may migrate information included in the at least one domain.

Abstract: An electrically-controlled water flow regulator for use with a poultry watering system receives potable water at a first, high flow rate and reduces the water flow rate of the water provided to watering valves that dispense water to the flock within a poultry house. A variable control valve uses a needle-shaped cone to engage a mating port inside the housing of the regulator. A motor controls the linear movement of the control valve in incremental steps to adjust the water flow rate provided to the flock. A feedback component enables the variable control valve to maintain the water flow rate at a desired set point for the flock. The desired set point for the flock is controlled or automated to match the growth of the flock over their growth cycle. An electrical controller and suitable cabling enable multiple regulators to be controlled efficiently and cost-effectively.

Abstract: Methods, systems, and apparatuses for creating collections of associated accounts for a migration process. An example system includes a processing device and memory that stores accounts in accordance with at least one domain. The processing device may create a collection of related accounts stored in accordance with the at least one domain based on active directory information of the stored accounts and information gathered from a survey and may migrate information included in the at least one domain.

Abstract: An electrically-controlled water pressure regulator for use with a poultry watering system receives potable water at a first high pressure level and reduces the water pressure level of the water provided to watering valves that dispense water to the flock within a poultry house. A variable control valve uses a needle-shaped cone to engage a round port inside the housing of the regulator. A stepper motor controls the liner movement of the control valve in incremental microsteps to adjust the water pressure level provided to the flock. A feedback component enables the variable control valve to maintain the water pressure level at a desired set point for the flock. The desired set point for the flock is controlled or automated to match the growth of the flock over their growth cycle. An electrical controller and suitable cabling enable multiple regulators to be controlled efficiently and cost-effectively.

Abstract: An electrically-controlled water pressure regulator for use with a poultry watering system receives potable water at a first high pressure level and reduces the water pressure level of the water provided to watering valves that dispense water to the flock within a poultry house. A variable control valve uses a needle-shaped cone to engage a round port inside the housing of the regulator. A stepper motor controls the liner movement of the control valve in incremental microsteps to adjust the water pressure level provided to the flock. A feedback component enables the variable control valve to maintain the water pressure level at a desired set point for the flock. The desired set point for the flock is controlled or automated to match the growth of the flock over their growth cycle. An electrical controller and suitable cabling enable multiple regulators to be controlled efficiently and cost-effectively.