Abstract: The disclosure relates to an antimicrobial hemostatic device having a substrate configured to be in contact with a bleed, where the substrate includes a hemostatic agent, a biguanide based antimicrobial agent, or a pharmaceutically acceptable salt thereof, and a binder configured to maintain the hemostatic agent with the substrate. The disclosure further includes methods of making and using such devices.

Abstract: A vertebral body replacement device includes a first member and a first footplate detachably connectable to the first member, a second member and a second footplate detachably connectable to the second member, and a central member detachably connectable to the first member. The first member is displaceable relative to the second member in response to rotation of the central member relative to the first member to adjust the length of the vertebral body replacement device. The first footplate includes a first surface oriented toward the first member, a second surface oriented away from the first member, and a sidewall extending between the first surface and the second surface. The first surface includes an alignment slot facing the first member. The alignment slot is open through the sidewall of the first footplate and configured to slidingly engage the first member to orient the first footplate relative to the first member.

Abstract: A vertebral body replacement device includes a first member and a first footplate detachably connectable to the first member, a second member and a second footplate detachably connectable to the second member, and a central member detachably connectable to the first member. The first member is axially displaceable relative to the second member in response to rotation of the central member relative to the first member to adjust the length of the vertebral body replacement device. The first member includes a pair of first fastener holes and a pair of second fastener holes angularly offset from the first fastener holes. The first footplate includes an aperture configured to align with one of the first fastener holes to orient the footplate in a first position or one of the second fastener holes to orient the footplate in a second position.

Abstract: A vertebral body replacement device includes a first member and a first footplate detachably connectable to the first member, a second member and a second footplate detachably connectable to the second member, and a central member detachably connectable to the first member. The first member is axially displaceable relative to the second member in response to rotation of the central member relative to the first member to adjust the length of the vertebral body replacement device. The first member includes a pair of first fastener holes and a pair of second fastener holes angularly offset from the first fastener holes. The first footplate includes an aperture configured to align with one of the first fastener holes to orient the footplate in a first position or one of the second fastener holes to orient the footplate in a second position.

Abstract: A vertebral body replacement device includes a first member and a first footplate detachably connectable to the first member, a second member and a second footplate detachably connectable to the second member, and a central member detachably connectable to the first member. The first member is displaceable relative to the second member in response to rotation of the central member relative to the first member to adjust the length of the vertebral body replacement device. The first footplate includes a first surface oriented toward the first member, a second surface oriented away from the first member, and a sidewall extending between the first surface and the second surface. The first surface includes an alignment slot facing the first member. The alignment slot is open through the sidewall of the first footplate and configured to slidingly engage the first member to orient the first footplate relative to the first member.

Abstract: A vertebral body replacement device includes a body member and a central rod member having two threaded portions and configured to be operatively associated with the body member. The device also includes a first end member and a second end member with the end members configured to threadingly engage the threaded portions of the central rod member. The body member and the two end members are further constructed to inhibit rotational movement of the two end members when the device is positioned within a space within a spine as the two end members will engage the adjacent respective vertebral bodies following rotational actuation of the central rod member causing the end members to move in an axial direction relative to the body member, thereby allowing the two end members to apply a force to the two vertebral bodies. A surgical instrument and method for using the device are also disclosed.

Abstract: A vertebral body replacement device includes a body member and a central rod member having two threaded portions and configured to be operatively associated with the body member. The device also includes a first end member and a second end member with the end members configured to threadingly engage the threaded portions of the central rod member. The body member and the two end members are further constructed to inhibit rotational movement of the two end members when the device is positioned within a space within a spine as the two end members will engage the adjacent respective vertebral bodies following rotational actuation of the central rod member causing the end members to move in an axial direction relative to the body member, thereby allowing the two end members to apply a force to the two vertebral bodies. A surgical instrument and method for using the device are also disclosed.

Abstract: A vertebral body replacement device includes a body member and a central rod member having two threaded portions and configured to be operatively associated with the body member. The device also includes a first end member and a second end member with the end members configured to threadingly engage the threaded portions of the central rod member. The body member and the two end members are further constructed to inhibit rotational movement of the two end members when the device is positioned within a space within a spine as the two end members will engage the adjacent respective vertebral bodies following rotational actuation of the central rod member causing the end members to move in an axial direction relative to the body member, thereby allowing the two end members to apply a force to the two vertebral bodies. A surgical instrument and method for using the device are also disclosed.

Abstract: A vertebral body replacement device includes a body member and a central rod member having two threaded portions and configured to be operatively associated with the body member. The device also includes a first end member and a second end member with the end members configured to threadingly engage the threaded portions of the central rod member. The body member and the two end members are further constructed to inhibit rotational movement of the two end members when the device is positioned within a space within a spine as the two end members will engage the adjacent respective vertebral bodies following rotational actuation of the central rod member causing the end members to move in an axial direction relative to the body member, thereby allowing the two end members to apply a force to the two vertebral bodies. A surgical instrument and method for using the device are also disclosed.

Abstract: A vertebral body replacement device includes a body member and a central rod member having two threaded portions and configured to be operatively associated with the body member. The device also includes a first end member and a second end member with the end members configured to threadingly engage the threaded portions of the central rod member. The body member and the two end members are further constructed to inhibit rotational movement of the two end members when the device is positioned within a space within a spine as the two end members will engage the adjacent respective vertebral bodies following rotational actuation of the central rod member causing the end members to move in an axial direction relative to the body member, thereby allowing the two end members to apply a force to the two vertebral bodies. A surgical instrument and method for using the device are also disclosed.

Abstract: An intervertebral implant includes a first plate and a second plate that is configured to be moveably engaged with the first plate along an axis of translation. Each plate defines at least one hole or recess for receiving a fastener that is configured to be fastened to a respective vertebrae. In one embodiment, a toothed surface is defined on both the first plate and the second plate. The toothed surface of the first plate is configured for engaging the toothed surface of the second plate such that translation of the second plate with respect to the first plate is limited in a single direction along the axis of translation.

Abstract: An implantable assembly includes an anchor member and a spacer. The anchor member has a hub portion and a shank portion. The spacer includes a central opening to receive bone fusion material and at least one passage for receiving the anchor member. In one embodiment, the passage includes first and second means for locking the anchor member in the passage against backout. The second means for locking the anchor member in the passage against backout includes means for centering the anchor member in the passage and means for stabilizing the anchor member in the passage. In addition, the second means for locking the anchor member in the passage against backout provides a mechanical advantage to assist in driving the screw into bone and mechanical advantage to assist in reversing the screw out of the spacer.

Abstract: A vertebral body replacement device includes a body member and a central rod member having two threaded portions and configured to be operatively associated with the body member. The device also includes a first end member and a second end member with the end members configured to threadingly engage the threaded portions of the central rod member. The body member and the two end members are further constructed to inhibit rotational movement of the two end members when the device is positioned within a space within a spine as the two end members will engage the adjacent respective vertebral bodies following rotational actuation of the central rod member causing the end members to move in an axial direction relative to the body member, thereby allowing the two end members to apply a force to the two vertebral bodies. A surgical instrument and method for using the device are also disclosed.

Abstract: A dynamic vertebral stabilization device for constraining motion of adjacent vertebrae is provided. The bone stabilization device comprises a first plate having a vertebral mating surface for positioning against a vertebrae, wherein the first plate defines a recess. The device further comprises a second plate having a vertebral mating surface for positioning against an adjacent vertebrae. The second plate includes a projection configured to travel in the recess of the first plate. The vertebral mating surface of the first plate is non-coplanar with respect to the vertebral mating surface of the second plate.

Abstract: A tissue retractor system includes first and second arms extending from a support assembly, and third and fourth arms extending from a support mechanism. Each arm includes a proximal span, a distal span, and a blade support between the proximal span and distal span. The retractor system features retractor units that can be used independently or in a nested arrangement. The system also includes instruments for inserting a spinal rod. A method for implanting a spinal rod through an incision includes the steps of inserting the spinal rod through a dividable tube, turning the rod subcutaneously toward a rod receiving anchor and advancing the rod subcutaneously toward the rod receiving anchor.

Abstract: An apparatus and method for reinforcing a bone fixation assembly includes a first connector element for coupling to a first bone screw assembly, a second connector element for coupling to a second bone screw assembly, and an elongated connecting element that interconnects the first connector element and second connector element. An end of the first connector element is adapted to engage an elongated fixation element in a first bone screw assembly, and an end of the second connector element is adapted to engage an elongated fixation element in a second bone screw assembly.

Abstract: An intervertebral implant includes an upper surface configured for engagement with a first vertebral body, and a lower surface configured for engagement with a second vertebral body. A wall extends between the upper surface and the lower surface, and forms a chamber for containing osteogenic material. At least a portion of the wall is collapsible from a first position associated with a first volume of the chamber to a second position associated with a second volume of the chamber. The second volume is less than the first volume.

Abstract: An implantable assembly includes an anchor member and a spacer. The anchor member has a hub portion and a shank portion. The spacer includes a central opening to receive bone fusion material and at least one passage for receiving the anchor member. In one embodiment, the passage includes first and second means for locking the anchor member in the passage against backout. The second means for locking the anchor member in the passage against backout includes means for centering the anchor member in the passage and means for stabilizing the anchor member in the passage. In addition, the second means for locking the anchor member in the passage against backout provides a mechanical advantage to assist in driving the screw into bone and mechanical advantage to assist in reversing the screw out of the spacer.

Abstract: A surgical instrument for insertion of an interbody fusion implant between adjacent vertebral bodies. The surgical instrument comprises a frame member, and a first and a second arm coupled to the frame member. Each arm includes a distal end region and a proximal end region, whereby the proximal end region of at least one arm is pivotably coupled to the frame member, and the distal end region of each arm defines a distractor plate. The distractor plate of each arm is configured to be positioned in direct contact with a vertebral body. A wedge is positioned between the first and second arms, and is configured to translate the interbody fusion implant along an axis between the proximal end region and the distal end region of the arms while adjusting a distance between the distractor plates of the arms via a rack and pinion.

Abstract: A tissue retractor system includes first and second arms extending from a support assembly, and third and fourth arms extending from a support mechanism. Each arm includes a proximal span, a distal span, and a blade support between the proximal span and distal span. The retractor system features retractor units that can be used independently or in a nested arrangement. The system also includes instruments for inserting a spinal rod. A method for implanting a spinal rod through an incision includes the steps of inserting the spinal rod through a dividable tube, turning the rod subcutaneously toward a rod receiving anchor and advancing the rod subcutaneously toward the rod receiving anchor.