Abstract: Presented herein are methods and compositions for the detection of specific beta-lactamases, including class A serine carbapenemases, metallo-beta-lactamases, AmpC beta-lactamases, and extended-spectrum beta-lactamases (ESBLs). The methods presented herein include methods that permit the detection of the presence of specific beta-lactamases in bacterial samples within as few as 2 to 10 minutes.

Abstract: Presented herein are methods, compositions, and kits for the detection of specific beta-lactamases, including class A serine carbapenemases, metallo-beta-lactamases, AmpC beta-lactamases, and extended-spectrum beta-lactamases (ESBLs). The methods presented herein include methods that permit the detection of the presence of specific beta-lactamases in bacterial samples within as few as 2 to 10 minutes.

Abstract: Described herein are flexible keratoprosthesis devices and uses thereof. The keratoprosthesis devices (100) can include an anchor body (110) and a plurality of flexible haptics (120), wherein the plurality of flexible haptics can be attached to and can be capable of extending radially from the anchor body. The flexible keratoprosthesis devices can be implanted into the eye via a minimally invasive technique.

Abstract: Disclosed are devices, systems, and methods for restoring vision to a subject. In one embodiment, the vision restoration device comprises a projector configured to project one or more digital images onto a central retina of the subject and one or more lenses coupled to the projector and configured to focus the one or more digital images. The vision restoration device can also comprise an extraocular component configured to be implanted within the subject and comprising one or more processors programmed to execute instructions stored in a memory to wirelessly receive the one or more digital images from an extracorporeal device. The intraocular projection component can be connected or coupled to the extraocular component by a trans-scleral communication wire configured to cross the sclera of the eye. The trans-scleral communication wire is configured to transmit digital data between the extraocular component and the intraocular projection component.

Abstract: A container includes a base, a cover and an intermediate part. The base includes a first room and a first lip extends from the open top of the base. The cover includes a second room and a second lip extends from the open bottom of the cover. The intermediate part includes a third room and a third lip extends from the open top of the third room. The cover is mounted to the base with the intermediate part located between the cover and the base. The cover seals the base and the intermediate part by one-time pressing action. The base includes at least one plate which is engaged with a recess formed to the outside of the second lip of the cover to secure the cover to the base.

Abstract: A box includes a base and a cover which is removably mounted to the base. The base includes a first room defined therein, and a connection strip extends from the periphery of the top opening of the base. A knob is formed on the connection strip. The cover includes a skirt extending from the periphery thereof so as to form a second room between the skirt and the cover. The skirt includes a U-shaped recess formed in the outside thereof such that the knob can be engaged with the U-shaped recess. The U-shaped recess includes a U-shaped inside wall formed between two outwardly projecting reinforcement ribs on the outside of the skirt to easily accommodate the knob therebetween.

Abstract: Presented herein are methods and compositions for the detection of specific beta-lactamases, including class A serine carbapenemases, metallo-beta-lactamases, AmpC beta-lactamases, and extended-spectrum beta-lactamases (ESBLs). The methods presented herein include methods that permit the detection of the presence of specific beta-lactamases in bacterial samples within as few as 2 to 10 minutes.

Abstract: A box includes a base and a cover which is removably mounted to the base. The base includes a first room defined therein, and a connection strip extends from the periphery of the top opening of the base. A knob is formed on the connection strip. The cover includes a skirt extending from the periphery thereof so as to form a second room between the skirt and the cover. The skirt includes a U-shaped recess formed in the outside thereof such that the knob is engaged with the U-shaped recess. The U-shaped recess includes a U-shaped inside wall formed between two reinforcement ribs and the outside of the skirt to easily accommodate the knob.

Abstract: Described herein are flexible keratoprosthesis devices and uses thereof. The keratoprosthesis devices (100) can include an anchor body (110) and a plurality of flexible haptics (120), wherein the plurality of flexible haptics can be attached to and can be capable of extending radially from the anchor body. The flexible keratoprosthesis devices can be implanted into the eye via a minimally invasive technique.

Abstract: Presented herein are methods for the detection of specific beta-lactamases, including class A serine carbapenemases, metallo-beta-lactamases, AmpC beta-lactamases, and extended-spectrum beta-lactamases (ESBLs). The methods presented herein include methods that permit the detection of the presence of specific beta-lactamases in bacterial samples within as few as 2 to 10 minutes.

Abstract: Disclosed are devices, systems, and methods for restoring vision to a subject. In one embodiment, the vision restoration device comprises a projector configured to project one or more digital images onto a central retina of the subject and one or more lenses coupled to the projector and configured to focus the one or more digital images. The vision restoration device can also comprise an extraocular component configured to be implanted within the subject and comprising one or more processors programmed to execute instructions stored in a memory to wirelessly receive the one or more digital images from an extracorporeal device. The intraocular projection component can be connected or coupled to the extraocular component by a trans-scleral communication wire configured to cross the sclera of the eye. The trans-scleral communication wire is configured to transmit digital data between the extraocular component and the intraocular projection component.

Abstract: Presented herein are solid supports on or in which a composition comprising a lysis reagent and an intracellular microorganism target detection reagent (e.g., an intracellular bacterial target detection reagent) is present in a dried form. Presented herein are also methods for detecting the presence of an intracellular microorganism target (e.g., an intracellular bacterial target) utilizing such solid supports. Further, presented herein are tablets as well as dry powders comprising a lysis reagent and an intracellular microorganism target detection reagent (e.g., an intracellular bacterial target detection reagent), and methods of using such tablets and dry powders to detect the presence of an intracellular microorganism target (e.g., an intracellular bacterial target).

Abstract: Presented herein are methods and compositions for the detection of specific beta-lactamases, including class A serine carbapenemases, metallo-beta-lactamases, AmpC beta-lactamases, and extended-spectrum beta-lactamases (ESBLs). The methods presented herein include methods that permit the detection of the presence of specific beta-lactamases in bacterial samples within as few as 2 to 10 minutes.

Abstract: Presented herein are solid supports on or in which a composition comprising a lysis reagent and an intracellular microorganism target detection reagent (e.g., an intracellular bacterial target detection reagent) is present in a dried form. Presented herein are also methods for detecting the presence of an intracellular microorganism target (e.g., an intracellular bacterial target) utilizing such solid supports. Further, presented herein are tablets as well as dry powders comprising a lysis reagent and an intracellular microorganism target detection reagent (e.g., an intracellular bacterial target detection reagent), and methods of using such tablets and dry powders to detect the presence of an intracellular microorganism target (e.g., an intracellular bacterial target).

Abstract: Presented herein are methods and compositions for the detection of specific beta-lactamases, including class A serine carbapenemases, metallo-beta-lactamases, AmpC beta-lactamases, and extended-spectrum beta-lactamases (ESBLs). The methods presented herein include methods that permit the detection of the presence of specific beta-lactamases in bacterial samples within as few as 2 to 10 minutes.

Abstract: Presented herein are solid supports on or in which a composition comprising a lysis reagent and an intracellular microorganism target detection reagent (e.g., an intracellular bacterial target detection reagent) is present in added form. Presented herein are also methods for detecting the presence of an intracellular microorganism target (e.g., an intracellular bacterial target) utilizing such solid supports. Further, presented herein are tablets as well as dry powders comprising a lysis reagent and an intracellular microorganism target detection reagent (e.g., an intracellular bacterial target detection reagent), and methods of using such tablets and dry powders to detect the presence of an intracellular microorganism target (e.g., an intracellular bacterial target).

Abstract: Presented herein are methods and compositions for the detection of specific beta-lactamases, including class A serine carbapenemases, metallo-beta-lactamases, AmpC beta-lactamases, and extended-spectrum beta-lactamases (ESBLs). The methods presented herein include methods that permit the detection of the presence of specific beta-lactamases in bacterial samples within as few as 2 to 10 minutes.

Abstract: Presented herein are kits for the detection of specific beta-lactamases, including class A serine carbapenemases, metallo-beta-lactamases, AmpC beta-lactamases, and extended-spectrum beta-lactamases (ESBLs). The kits presented herein include kits that permit the detection of the presence of specific beta-lactamases in bacterial samples within as few as 2 to 10 minutes.