Patents by Inventor Charles Zepp

Charles Zepp has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NANOCARRIERS POSSESSING COMPONENTS WITH DIFFERENT RATES OF RELEASE
    Publication number: 20200390881
    Abstract: This invention relates to compositions, and related methods, of synthetic nanocarriers that comprise immunomodulatory agents and antigens that are differentially released from the synthetic nanocarriers.
    Type: Application
    Filed: January 27, 2020
    Publication date: December 17, 2020
    Applicant: Selecta Biosciences, Inc.
    Inventors: Grayson B. Lipford, Charles Zepp, Yun Gao, Mark J. Keegan, Sam Baldwin, Fen-ni Fu, Lloyd Johnston
  • IMMUNOMODULATORY AGENT-POLYMERIC COMPOUNDS
    Publication number: 20180256709
    Abstract: This invention relates to compositions, and related compounds and methods, of conjugates of immunomodulatory agents and polymers or unit(s) thereof. The conjugates may be contained within synthetic nanocarriers, and the immunomodulatory agents may be released from the synthetic nanocarriers in a pH sensitive manner.
    Type: Application
    Filed: February 5, 2018
    Publication date: September 13, 2018
    Applicant: Selecta Biosciences, Inc.
    Inventors: Charles Zepp, Grayson B. Lipford, Yun Gao, Lloyd Johnston, Fen-ni Fu, Mark J. Keegan, Sam Baldwin
  • Modified nicotinic compounds and related methods
    Patent number: 9994443
    Abstract: Provided herein are compounds and related composition and methods that may be used to raise an antibody response to nicotinic compounds, in some embodiments.
    Type: Grant
    Filed: November 4, 2011
    Date of Patent: June 12, 2018
    Assignee: Selecta Biosciences, Inc.
    Inventors: Charles Zepp, Yun Gao
  • DOSE SELECTION OF ADJUVANTED SYNTHETIC NANOCARRIERS
    Publication number: 20180043023
    Abstract: Disclosed are synthetic nanocarrier compositions with coupled adjuvant compositions as well as related methods.
    Type: Application
    Filed: August 23, 2017
    Publication date: February 15, 2018
    Applicant: Selecta Biosciences, Inc.
    Inventors: Petr Ilyinskii, Grayson B. Lipford, Charles Zepp
  • Immunomodulatory agent-polymeric compounds
    Patent number: 9884112
    Abstract: This invention relates to compositions, and related compounds and methods, of conjugates of immunomodulatory agents and polymers or unit(s) thereof. The conjugates may be contained within synthetic nanocarriers, and the immunomodulatory agents may be released from the synthetic nanocarriers in a pH sensitive manner.
    Type: Grant
    Filed: March 13, 2015
    Date of Patent: February 6, 2018
    Assignee: Selecta Biosciences, Inc.
    Inventors: Charles Zepp, Grayson B. Lipford, Yun Gao, Lloyd Johnston, Fen-ni Fu, Mark J. Keegan, Sam Baldwin
  • Dose selection of adjuvanted synthetic nanocarriers
    Patent number: 9764031
    Abstract: Disclosed are synthetic nanocarrier compositions with coupled adjuvant compositions as well as related methods.
    Type: Grant
    Filed: May 20, 2015
    Date of Patent: September 19, 2017
    Assignee: Selecta Biosciences, Inc.
    Inventors: Petr Ilyinskii, Grayson B. Lipford, Charles Zepp
  • DOSE SELECTION OF ADJUVANTED SYNTHETIC NANOCARRIERS
    Publication number: 20150328309
    Abstract: Disclosed are synthetic nanocarrier compositions with coupled adjuvant compositions as well as related methods.
    Type: Application
    Filed: May 20, 2015
    Publication date: November 19, 2015
    Applicant: Selecta Biosciences, Inc.
    Inventors: Petr Ilyinskii, Grayson B. Lipford, Charles Zepp
  • IMMUNOMODULATORY AGENT-POLYMERIC COMPOUNDS
    Publication number: 20150328300
    Abstract: This invention relates to compositions, and related compounds and methods, of conjugates of immunomodulatory agents and polymers or unit(s) thereof. The conjugates may be contained within synthetic nanocarriers, and the immunomodulatory agents may be released from the synthetic nanocarriers in a pH sensitive manner.
    Type: Application
    Filed: March 13, 2015
    Publication date: November 19, 2015
    Applicant: Selecta Biosciences, Inc.
    Inventors: Charles Zepp, Grayson B. Lipford, Yun Gao, Lloyd Johnston, Fen-ni Fu, Mark J. Keegan, Sam Baldwin
  • Dose selection of adjuvanted synthetic nanocarriers
    Patent number: 9066978
    Abstract: Disclosed are synthetic nanocarrier compositions with coupled adjuvant compositions as well as related methods.
    Type: Grant
    Filed: May 26, 2011
    Date of Patent: June 30, 2015
    Assignee: Selecta Biosciences, Inc.
    Inventors: Petr Ilyinskii, Grayson B. Lipford, Charles Zepp
  • Immunomodulatory agent-polymeric compounds
    Patent number: 9006254
    Abstract: This invention relates to compositions, and related compounds and methods, of conjugates of immunomodulatory agents and polymers or unit(s) thereof. The conjugates may be contained within synthetic nanocarriers, and the immunomodulatory agents may be released from the synthetic nanocarriers in a pH sensitive manner.
    Type: Grant
    Filed: December 23, 2013
    Date of Patent: April 14, 2015
    Assignee: Selecta Biosciences, Inc.
    Inventors: Charles Zepp, Grayson B. Lipford, Yun Gao, Lloyd Johnston, Fen-ni Fu, Mark J. Keegan, Sam Baldwin
  • Multi wavelength excitation/emission authentication and detection scheme
    Patent number: 8840029
    Abstract: A system and method for authentication of secure products is disclosed. The security feature contains a first component in the form of an emitter capable of emitting light in response to external pump light. The security feature also contains a second component in the form of a taggant that absorbs light in a spectrally narrow range compared to the broader excitation spectrum of the first material. In this manner the emitter and taggant work in combination with one another to create an emission response significantly dependent on the illumination wavelengths and unique to the specific combination of the components. The emitter and taggant can be in the form of a mixture. Further the emitter and taggant may be applied in close proximity to one another, such as within two separate coating layers on a suitable substrate.
    Type: Grant
    Filed: January 18, 2012
    Date of Patent: September 23, 2014
    Assignee: Spectra Systems Corporation
    Inventors: Nabil Lawandy, Andrei Smuk, Leif Olson, Charles Zepp
  • TARGETED SYNTHETIC NANOCARRIERS WITH PH SENSITIVE RELEASE OF IMMUNOMODULATORY AGENTS
    Publication number: 20140242173
    Abstract: This invention relates to compositions, and related methods, of synthetic nanocarriers that target sites of action in cells, such as antigen presenting cells (APCs), and comprise immunomodulatory agents that dissociate from the synthetic nanocarriers in a pH sensitive manner. Also disclosed are compositions and methods relating to synthetic nanocarriers that encapsulate labile immunomodulatory agents that dissociate from the synthetic nanocarriers in a pH sensitive manner.
    Type: Application
    Filed: May 8, 2014
    Publication date: August 28, 2014
    Applicant: Selecta Biosciences, Inc.
    Inventors: Charles Zepp, Yun Gao, Mark J. Keegan, Sam Baldwin, Fen-ni Fu, Lloyd Johnston, Grayson B. Lipford
  • IMMUNOMODULATORY AGENT-POLYMERIC COMPOUNDS
    Publication number: 20140193453
    Abstract: This invention relates to compositions, and related compounds and methods, of conjugates of immunomodulatory agents and polymers or unit(s) thereof. The conjugates may be contained within synthetic nanocarriers, and the immunomodulatory agents may be released from the synthetic nanocarriers in a pH sensitive manner.
    Type: Application
    Filed: December 23, 2013
    Publication date: July 10, 2014
    Applicant: SELECTA BIOSCIENCES, INC.
    Inventors: CHARLES ZEPP, GRAYSON B. LIPFORD, YUN GAO, LLOYD JOHNSTON, FEN-NI FU, MARK J. KEEGAN, SAM BALDWIN
  • TARGETED SYNTHETIC NANOCARRIERS WITH PH SENSITIVE RELEASE OF IMMUNOSTIMULATORY AGENTS
    Publication number: 20140030344
    Abstract: This invention relates to compositions, and related methods, of synthetic nanocarriers that target sites of action in cells, such as antigen presenting cells (APCs), and comprise immunomodulatory agents that dissociate from the synthetic nanocarriers in a pH sensitive manner. Also disclosed are compositions and methods relating to synthetic nanocarriers that encapsulate labile immunomodulatory agents that dissociate from the synthetic nanocarriers in a pH sensitive manner.
    Type: Application
    Filed: July 22, 2013
    Publication date: January 30, 2014
    Applicant: Selecta Biosciences, Inc.
    Inventors: Charles Zepp, Yun Gao, Mark J. Keegan, Sam Baldwin, Fen-ni Fu, Lloyd Johnston, Grayson B. Lipford
  • Immunomodulatory agent-polymeric compounds
    Patent number: 8629151
    Abstract: This invention relates to compositions, and related compounds and methods, of conjugates of immunomodulatory agents and polymers or unit(s) thereof. The conjugates may be contained within synthetic nanocarriers, and the immunomodulatory agents may be released from the synthetic nanocarriers in a pH sensitive manner.
    Type: Grant
    Filed: May 26, 2010
    Date of Patent: January 14, 2014
    Assignee: Selecta Biosciences, Inc.
    Inventors: Charles Zepp, Grayson B. Lipford, Yun Gao, Lloyd Johnston, Fen-ni Fu, Mark J. Keegan, Sam Baldwin
  • MULTI WAVELENGTH EXCITATION/EMISSION AUTHENTICATION AND DETECTION SCHEME
    Publication number: 20130182241
    Abstract: A system and method for authentication of secure products is disclosed. The security feature contains a first component in the form of an emitter capable of emitting light in response to external pump light. The security feature also contains a second component in the form of a taggant that absorbs light in a spectrally narrow range compared to the broader excitation spectrum of the first material. In this manner the emitter and taggant work in combination with one another to create an emission response significantly dependent on the illumination wavelengths and unique to the specific combination of the components. The emitter and taggant can be in the form of a mixture. Further the emitter and taggant may be applied in close proximity to one another, such as within two separate coating layers on a suitable substrate.
    Type: Application
    Filed: January 18, 2012
    Publication date: July 18, 2013
    Applicant: SPECTRA SYSTEMS CORPORATION
    Inventors: Nabil Lawandy, Andrei Smuk, Leif Olson, Charles Zepp
  • SYNTHETIC NANOCARRIERS WITH REACTIVE GROUPS THAT RELEASE BIOLOGICALLY ACTIVE AGENTS
    Publication number: 20120171229
    Abstract: This invention relates to compositions, and related compounds and methods, of conjugates of synthetic nanocarriers, or components thereof, and biologically active agents, such as immunomodulatory agents, antigens, anticancer agents or antiviral agents. The biologically active agents are released from the synthetic nanocarriers in the presence of a reducing agent or by reaction with a thiol.
    Type: Application
    Filed: December 30, 2011
    Publication date: July 5, 2012
    Applicant: Selecta Biosciences, Inc.
    Inventors: Charles Zepp, Yun Gao
  • MODIFIED NICOTINIC COMPOUNDS AND RELATED METHODS
    Publication number: 20120114677
    Abstract: Provided herein are compounds and related composition and methods that may be used to raise an antibody response to nicotinic compounds, in some embodiments.
    Type: Application
    Filed: November 4, 2011
    Publication date: May 10, 2012
    Applicant: Selecta Biosciences, Inc.
    Inventors: Charles Zepp, Yun Gao
  • DOSE SELECTION OF ADJUVANTED SYNTHETIC NANOCARRIERS
    Publication number: 20120027806
    Abstract: Disclosed are synthetic nanocarrier compositions with coupled adjuvant compositions as well as related methods.
    Type: Application
    Filed: May 26, 2011
    Publication date: February 2, 2012
    Applicant: Selecta Biosciences, Inc.
    Inventors: Petr Ilyinskii, Grayson B. Lipford, Charles Zepp
  • NANOCARRIER COMPOSITIONS WITH UNCOUPLED ADJUVANT
    Publication number: 20110293700
    Abstract: Disclosed are synthetic nanocarrier compositions with separate adjuvant compositions as well as related methods.
    Type: Application
    Filed: May 26, 2011
    Publication date: December 1, 2011
    Applicant: Selecta Biosciences, Inc.
    Inventors: Robert L. Bratzler, Lloyd Johnston, Grayson B. Lipford, Charles Zepp