Patents by Inventor Charlie D. Chen

Charlie D. Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DIARYLHYDANTOIN COMPOUNDS
    Publication number: 20240132452
    Abstract: The present invention relates to diarylhydantoin compounds, including diarylthiohydantoins, and methods for synthesizing them and using them in the treatment of hormone refractory prostate cancer.
    Type: Application
    Filed: June 13, 2023
    Publication date: April 25, 2024
    Applicant: The Regents of the University of California
    Inventors: Charles L. Sawyers, Michael Jung, Charlie D. Chen, Samedy Ouk, Derek Welsbie, Chris Tran, John Wongvipat, Dongwon Yoo
  • DIARYLHYDANTOIN COMPOUNDS
    Publication number: 20230109968
    Abstract: The present invention relates to diarylhydantoin compounds, including diarylthiohydantoins, and methods for synthesizing them and using them in the treatment of hormone refractory prostate cancer.
    Type: Application
    Filed: July 13, 2022
    Publication date: April 13, 2023
    Applicant: The Regents of the University of California
    Inventors: Charles L. SAWYERS, Michael JUNG, Charlie D. CHEN, Samedy OUK, Derek WELSBIE, Chris TRAN, John WONGVIPAT, Dongwon YOO
  • DIARYLHYDANTOIN COMPOUNDS
    Publication number: 20210238145
    Abstract: The present invention relates to diarylhydantoin compounds, including diarylthiohydantoins, and methods for synthesizing them and using them in the treatment of hormone refractory prostate cancer.
    Type: Application
    Filed: November 3, 2020
    Publication date: August 5, 2021
    Applicant: The Regents of the University of California
    Inventors: Charles L. SAWYERS, Michael JUNG, Charlie D. CHEN, Samedy OUK, Derek WELSBIE, Chris TRAN, John WONGVIPAT, Dongwon YOO
  • DIARYLHYDANTOIN COMPOUNDS
    Publication number: 20200079741
    Abstract: The present invention relates to diarylhydantoin compounds, including diarylthiohydantoins, and methods for synthesizing them and using them in the treatment of hormone refractory prostate cancer.
    Type: Application
    Filed: July 17, 2019
    Publication date: March 12, 2020
    Applicant: The Regents of the University of California
    Inventors: Charles L. SAWYERS, Michael JUNG, Charlie D. CHEN, Samedy OUK, Derek WELSBIE, Chris TRAN, John WONGVIPAT, Dongwon YOO
  • DIARYLHYDANTOIN COMPOUNDS
    Publication number: 20190210974
    Abstract: The present invention relates to diarylhydantoin compounds, including diarylthiohydantoins, and methods for synthesizing them and using them in the treatment of hormone refractory prostate cancer.
    Type: Application
    Filed: December 21, 2018
    Publication date: July 11, 2019
    Applicant: The Regents of the University of California
    Inventors: Charles L. SAWYERS, Michael JUNG, Charlie D. CHEN, Samedy OUK, Derek WELSBIE, Chris TRAN, John WONGVIPAT, Dongwon YOO
  • Diarylhydantoin Compounds
    Publication number: 20180086718
    Abstract: The present invention relates to diarylhydantoin compounds, including diarylthiohydantoins, and methods for synthesizing them and using them in the treatment of hormone refractory prostate cancer.
    Type: Application
    Filed: July 20, 2017
    Publication date: March 29, 2018
    Applicant: The Regents of the University of California
    Inventors: Charles L. Sawyers, Michael Jung, Charlie D. Chen, Samedy Ouk, Derek Welsbie, Chris Tran, John Wongvipat, Dongwon Yoo
  • Treatment of hyperproliferative disorders with diarylhydantoin compounds
    Patent number: 9126941
    Abstract: The present invention relates to diarylhydantoin compounds, including diarylthiohydantoins, and methods for synthesizing them and using them in the treatment of hormone refractory prostate cancer.
    Type: Grant
    Filed: April 17, 2012
    Date of Patent: September 8, 2015
    Assignee: The Regents of the University of California
    Inventors: Charles L. Sawyers, Michael E. Jung, Charlie D. Chen, Samedy Ouk, Chris Tran, John Wongvipat
  • DIARYLHYDANTOIN COMPOUNDS
    Publication number: 20150112082
    Abstract: The present invention relates to diarylhydantoin compounds, including diarylthiohydantoins, and methods for synthesizing them and using them in the treatment of hormone refractory prostate cancer.
    Type: Application
    Filed: September 25, 2014
    Publication date: April 23, 2015
    Inventors: Charles L. Sawyers, Michael Jung, Charlie D. Chen, Samedy Ouk, Derek Welsbie, Chirs Tran, John Wongvipat, Dongwon Yoo
  • DIARYLTHIOHYDANTOIN COMPOUNDS
    Publication number: 20140343111
    Abstract: The present invention relates to diarylthiohydantoin compounds and methods for synthesizing them and using them in the treatment of hormone refractory prostate cancer.
    Type: Application
    Filed: December 20, 2013
    Publication date: November 20, 2014
    Applicant: The Regents of the University of California
    Inventors: Charles L. Sawyers, Michael E. Jung, Charlie D. Chen, Samedy Ouk, Chris Tran, John Wongvipat, Dongwon Yoo
  • Treatment of hyperproliferative disorders with diarylhydantoin compounds
    Patent number: 8658681
    Abstract: The present invention relates to diarylhydantoin compounds, including diarylthiohydantoins, and methods for synthesizing them and using them in the treatment of hormone refractory prostate cancer.
    Type: Grant
    Filed: April 17, 2012
    Date of Patent: February 25, 2014
    Assignee: The Regents of the University of California
    Inventors: Charles L. Sawyers, Michael E. Jung, Charlie D. Chen, Samedy Ouk, Chris Tran, John Wongvipat
  • DIARYLHYDANTOIN COMPOUNDS
    Publication number: 20130034501
    Abstract: The present invention relates to diarylhydantoin compounds, including diarylthiohydantoins, and methods for synthesizing them and using them in the treatment of hormone lefiactory prostate cancer.
    Type: Application
    Filed: September 14, 2012
    Publication date: February 7, 2013
    Applicant: The Regents of the University of California
    Inventors: Charles L. Sawyers, Michael E. Jung, Charlie D. Chen, Samedy Ouk, Derek Welsbie, Chris Tran, John Wongvipat, Dongwon Yoo
  • TREATMENT OF HYPERPROLIFERATIVE DISORDERS WITH DIARYLHYDANTOIN COMPOUNDS
    Publication number: 20120295944
    Abstract: The present invention relates to diarylhydantoin compounds, including diarylthiohydantoins, and methods for synthesizing them and using them in the treatment of hormone refractory prostate cancer.
    Type: Application
    Filed: April 17, 2012
    Publication date: November 22, 2012
    Applicant: The Regents of the University of California
    Inventors: Charles L. Sawyers, Michael E. Jung, Charlie D. Chen, Samedy Ouk, Derek Welsbie, Chris Tran, John Wongvipat, Dongwon Yoo
  • Treatment of hyperproliferative disorders with diarylhydantoin compounds
    Patent number: 8183274
    Abstract: The present invention relates to diarylhydantoin compounds, including diarylthiohydantoins, and methods for synthesizing them and using them in the treatment of hormone refractory prostate cancer.
    Type: Grant
    Filed: February 18, 2010
    Date of Patent: May 22, 2012
    Assignee: The Regents of the University of California
    Inventors: Charles L. Sawyers, Michael E. Jung, Charlie D. Chen, Samedy Ouk, Chris Tran, John Wongvipat
  • Methods and materials for assessing prostate cancer therapies
    Patent number: 8034548
    Abstract: Using microarray-based profiling of isogenic prostate cancer xenograft models, we found that a modest (2-5 fold) increase in androgen receptor (AR) mRNA was the only expression change consistently associated with developing resistance to antiandrogen therapy. Increased levels of AR confer resistance to anti-androgens by amplifying signal output from low levels of residual ligand and altering the normal response to antagonists. This invention provides cell based assays for use in the examination of new therapeutic modalities and provides insight toward the design of novel antiandrogens.
    Type: Grant
    Filed: December 16, 2004
    Date of Patent: October 11, 2011
    Assignee: The Regents of the University of California
    Inventors: Charles L. Sawyers, Charlie D. Chen, Derek S. Welsbie
  • DIARYLHYDANTOIN COMPOUNDS
    Publication number: 20100210665
    Abstract: The present invention relates to diarylhydantoin compounds, including diarylthiohydantoins, and methods for synthesizing them and using them in the treatment of hormone refractory prostate cancer.
    Type: Application
    Filed: February 18, 2010
    Publication date: August 19, 2010
    Applicant: The Regents of the University of California
    Inventors: Charles L. Sawyers, Michael E. Jung, Charlie D. Chen, Samedy Ouk, Derek Welsbie, Chris Tran, John Wongvipat
  • TREATMENT OF HYPERPROLIFERATIVE DISORDERS WITH DIARYLHYDANTOIN COMPOUNDS
    Publication number: 20100172975
    Abstract: The present invention relates to diarylhydantoin compounds, including diarylthiohydantoins, and methods for synthesizing them and using them in the treatment of hormone refractory prostate cancer.
    Type: Application
    Filed: February 18, 2010
    Publication date: July 8, 2010
    Applicant: The Regents of the University of California
    Inventors: Charles L. Sawyers, Michael E. Jung, Charlie D. Chen, Samedy Ouk, Derek Welsbie, Chris Tran, John Wongvipat, Dongwon Yoo
  • Methods and materials for assessing prostate cancer therapies and compounds
    Patent number: 7718684
    Abstract: A modest (2-5 fold) increase in androgen receptor (AR) mRNA is the only expression change consistently associated with developing resistance to antiandrogen therapy. Increased levels of AR confer resistance to anti-androgens by amplifying signal output from low levels of residual ligand and altering the normal response to antagonists. This invention provides cell based assays for use in the examination of new therapeutic modalities and provides for the design of novel antiandrogen compounds.
    Type: Grant
    Filed: February 23, 2005
    Date of Patent: May 18, 2010
    Assignee: The Regents of the University of California
    Inventors: Michael E. Jung, Samedy Ouk, Charles L. Sawyers, Charlie D. Chen, Derek Welsbie
  • Diarylhydantoin compounds
    Patent number: 7709517
    Abstract: The present invention relates to diarylhydantoin compounds, including diarylthiohydantoins, and methods for synthesizing them and using them in the treatment of hormone refractory prostate cancer.
    Type: Grant
    Filed: May 15, 2006
    Date of Patent: May 4, 2010
    Assignee: The Regents of the University of California
    Inventors: Charles L. Sawyers, Michael E. Jung, Charlie D. Chen, Samedy Ouk, Derek Welsbie, Chris Tran, John Wongvipat, Dongwon Yoo