Patents by Inventor Charlotte Handford

Charlotte Handford has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND DEVICES FOR GENERATING EMBRYOS IN VITRO FROM EMBRYONIC STEM CELLS
    Publication number: 20240124835
    Abstract: Disclosed herein include methods, compositions, culture media, and devices for in vitro culture of synthetic embryos from mammalian pluripotent stem cells. The in vitro embryo model is generated with embryonic and extraembryonic lineages derived from embryonic stem cells through transcription-factor-mediated reprogramming and can undergo advanced development to late headfold stages.
    Type: Application
    Filed: October 11, 2023
    Publication date: April 18, 2024
    Inventors: Magdalena Zernicka-Goetz, Gianluca Amadei, Charlotte Handford
  • METHODS, CULTURE MEDIAS AND DEVICES FOR GENERATING EMBRYOS IN VITRO FROM STEM CELLS
    Publication number: 20230236171
    Abstract: Disclosed herein include methods and compositions for culture medias for in vitro culture of synthetic embryos from mammalian pluripotent stem cells and extra-embryonic stem cells. The methods and compositions described herein can generate synthetic embryos at different developmental stage reaching early organogenesis and beyond. Disclosed herein also include an embryo culturing system and methods of using same.
    Type: Application
    Filed: December 13, 2022
    Publication date: July 27, 2023
    Inventors: Magdalena D. Zernicka-Goetz, Gianluca Amadei, Charlotte Handford