Patents by Inventor Charlotte Harkjaer Fynbo

Charlotte Harkjaer Fynbo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel N-Terminally Modified Insulin Derivatives
    Publication number: 20140315797
    Abstract: The invention is related to novel N-terminally modified insulin derivatives, pharmaceutical compositions comprising such and methods of making such.
    Type: Application
    Filed: October 14, 2011
    Publication date: October 23, 2014
    Inventors: Peter Madsen, Per Balschmidt, Svend Havelund, Thomas Hoeg-Jensen, Thomas Boerglum Kjeldsen, Charlotte Harkjaer Fynbo
  • Insulin derivatives
    Patent number: 8722620
    Abstract: The present invention is related to insulin derivatives having a side chain attached to an ?-amino group of a Lys residue present in the A-chain or to an ?-amino group of a Lys residue in the B-chain.
    Type: Grant
    Filed: February 27, 2007
    Date of Patent: May 13, 2014
    Assignee: Novo Nordisk A/S
    Inventors: Charlotte Harkjaer Fynbo, Ib Jonassen, Thomas Børglum Kjeldsen, Peter Madsen, Patrick William Garibay, Janos Tibor Kodra, Thomas Hoeg-Jensen, Tina Møller Tagmose
  • Cleavage of fusion proteins using Granzyme B protease
    Patent number: 8541200
    Abstract: A method for the preparation of a polypeptide of interest in authentic form by enzymatic cleavage of fusion proteins using Granzyme B protease (EC 3.4.21.79). There is also provided fusion proteins comprising a polypeptide of interest and a fusion partner, wherein the junction region between the polypeptide of interest and the fusion partner comprises a Granzyme B protease cleavage site adjacent to the polypeptide of interest, and a human Granzyme B protease variant wherein the Cystein residue no. 228 (chymotrypsinogen numbering) is mutated to Phenylalanine.
    Type: Grant
    Filed: April 23, 2004
    Date of Patent: September 24, 2013
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Rikke Hoegh Lorentsen, Charlotte Harkjaer Fynbo
  • STABLE NON-AQUEOUS LIQUID PHARMACEUTICAL COMPOSITIONS COMPRISING AN INSULIN
    Publication number: 20120196800
    Abstract: The invention describes a non-aqueous liquid pharmaceutical composition comprising at least one lipid and at least one insulin. Also described is a method of producing a pharmaceutical composition comprising a lipid and a method of purifying a lipid, a cosolvent, a surfactant or a pharmaceutical composition comprising a lipid.
    Type: Application
    Filed: September 16, 2010
    Publication date: August 2, 2012
    Applicant: Novo Nordisk A/S
    Inventors: Helle Naver, Florian Anders Föger, Thomas Hoeg-Jensen, Charlotte Harkjaer Fynbo
  • Insulin Derivatives
    Publication number: 20090137454
    Abstract: The present invention is related to insulin derivatives having a side chain attached to an ?-amino group of a Lys residue present in the A-chain or to an ?-amino group of a Lys residue in the B-chain.
    Type: Application
    Filed: February 27, 2007
    Publication date: May 28, 2009
    Applicant: NOVO NORDISK A/S
    Inventors: Charlotte Harkjaer Fynbo, Ib Jonassen, Thomas Borglum Kjeldsen, Peter Madsen, Patrick William Garibay, Janos Tibor Kodra, Thomas Hoeg-Jensen, Tina Moller Tagmose