Patents by Inventor Charlotte Madore

Charlotte Madore has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Targeting Apolipoprotein E (APOE) in Neurologic Disease
    Publication number: 20180155414
    Abstract: Methods for treating neurologic diseases, e.g., amyotrophic lateral sclerosis (ALS) and multiple sclerosis, by modulating the APOE-TGFbeta pathway. The methods include administering one or more inhibitory nucleic acids targeting Trem2 and/or ApoE), sense nucleic acids encoding Egr1 and/or Mertk, and/or antibodies that bind to and inhibit Trem2 and/or ApoE.
    Type: Application
    Filed: September 8, 2017
    Publication date: June 7, 2018
    Inventors: Oleg Butovsky, Susanne Krasemann, Charlotte Madore, Howard Weiner
  • Targeting Apolipoprotein E (APOE) in Neurologic Disease
    Publication number: 20170334977
    Abstract: Methods for treating neurologic diseases, e.g., amyotrophic lateral sclerosis (ALS) and multiple sclerosis, by modulating the APOE-TGFbeta pathway. The methods include administering one or more inhibitory nucleic acids targeting Trem2 and/or ApoE), sense nucleic acids encoding Egr1 and/or Mertk, and/or antibodies that bind to and inhibit Trem2 and/or ApoE.
    Type: Application
    Filed: October 20, 2015
    Publication date: November 23, 2017
    Inventors: Oleg Butovsky, Susanne Krasemann, Charlotte Madore, Howard Weiner