Patents by Inventor Chase C. Smith

Chase C. Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyrido [2,3-D] pyrimidines and their use as kinase inhibitors
    Patent number: 8518958
    Abstract: The present invention provides derivatives of pyrido[2,3-d]pyrimidin-7-one. These compounds are kinase inhibitors, including compounds that show anti-proliferative activity, including against tumor cells, and are useful in the treatment of diseases including cancer.
    Type: Grant
    Filed: October 16, 2007
    Date of Patent: August 27, 2013
    Assignee: Forma Therapeutics, Inc.
    Inventors: Krishna K. Murthi, Rebecca Casaubon, Arthur F. Kluge, Chase C. Smith, Joachim Vogt
  • Synthesis of methotrexate-containing heterodimeric molecules
    Patent number: 7230101
    Abstract: The present invention relates to novel compositions of methotrexate-containing heterodimeric probe molecules, also known as chemical inducers of dimerization (CID), useful in three-hybrid assays. The invention further relates to synthesis of said compositions and their intermediates. Another aspect of the invention is a method for using the heterodimeric probe molecules described herein in drug screens to identify potential protein targets to a given ligand, optimize protein-ligand interactions, or identify potential ligands for a given protein target.
    Type: Grant
    Filed: August 28, 2003
    Date of Patent: June 12, 2007
    Assignee: GPC Biotech, Inc.
    Inventors: Krishna K. Murthi, Chase C. Smith
  • Tricyclic and tetracyclic taxane intermediates
    Publication number: 20030050485
    Abstract: The synthesis of taxol and other tricyclic and tetracyclic taxanes.
    Type: Application
    Filed: July 12, 2002
    Publication date: March 13, 2003
    Applicant: Florida State University
    Inventors: Robert A. Holton, Carmen Somoza, Hyeong Baik Kim, Mitsuru Shindo, Ronald J. Biediger, P. Douglas Boatman, Chase C. Smith, Feng Liang, Krishna K. Murthi
  • Tricyclic and tetracyclic taxane intermediates
    Publication number: 20010053857
    Abstract: The synthesis of taxol and other tricyclic and tetracyclic taxanes.
    Type: Application
    Filed: July 17, 2001
    Publication date: December 20, 2001
    Inventors: Robert A. Holton, Carmen Somoza, Hyeong Baik Kim, Mitsuru Shindo, Ronald J. Biediger, P. Douglas Boatman, Chase C. Smith, Feng Liang, Krishna K. Murthi