Abstract: The present disclosure provides coupling methods and systems for producing peptides or proteins using semi-continuous or continuous manufacturing techniques to enable rapid production of peptides and proteins using solid phase peptide synthesis (SPPS). The disclosure provides a higher degree of process control for peptide and protein product manufacturing using semi-continuous or continuous manufacturing techniques with inline analytics and automation.

Abstract: Methods, non-transitory computer readable media, and content customization apparatuses that provide instructions to an optical scanner device, configured to be capable of producing a localization element on the surface of the test object, to scan the localization element to a plurality of points across the surface of the test object in a two-dimensional scan pattern. Image data of an image of the localization element at each of the plurality of points along the surface of the test object is obtained. The obtained image data is processed to determine a surface profile for the test object. The two-dimensional scan pattern reduces surface texture errors in the surface profile.