Abstract: Provided herein are N-acetylgalactosamine (GalNAc)-derived compounds, modified oligonucleotides, and methods of modulating protein function and treating diseases, disorders, and symptoms in a subject.

Abstract: A dispersion device configured to disperse a coloring material to a cloth substrate, comprising a hollow housing that contains the coloring material therein, the hollow housing being configured to fracture upon application of a force to the housing and disperse the coloring material to the cloth substrate to color the cloth substrate.

Abstract: The present disclosure provides, e.g., compounds, compositions, kits, methods of synthesis, and methods of use, involving epipolythiodiketopiperazines and polythiodiketopiperazines.

Abstract: The present disclosure provides, e.g., compounds, compositions, kits, methods of synthesis, and methods of use, involving epipolythiodiketopiperazines and polythiodiketopiperazines.

Abstract: A dispersion device configured to disperse a coloring material to a cloth substrate, comprising a hollow housing that contains the coloring material therein, the hollow housing being configured to fracture upon application of a force to the housing and disperse the coloring material to the cloth substrate to color the cloth substrate.

Abstract: Methods and kits are provided for tie-dyeing various materials. A garment or other object is soaked using water or a different liquid, excess water is removed, the object is gathered and tied, and at least one dye is applied to the object. The dyed object is then placed in a heat-resistant container and heated in a heat source such as a microwave. This allows the dye to set more rapidly than via conventional means.

Abstract: The present disclosure provides, e.g., compounds, compositions, kits, methods of synthesis, and methods of use, involving epipolythiodiketopiperazines and polythiodiketopiperazines.

Abstract: A pre-hung barn door hardware system is disclosed. The -hung barn door hardware system includes a rail having a plurality of rail holes disposed along a length of the rail; a plurality of spacers each of the plurality of spacers having a spacer hole; a track having a plurality of track holes disposed along the length of the track; a plurality of bolts, each of the plurality of bolts extending through one of the plurality of rail holes, a spacer hole in one of the plurality of spacers, and one of the plurality of track holes; and a plurality of nuts, each one of the plurality of nuts being coupled with a corresponding one of the plurality of bolts.

Abstract: A safety shut-off system and method are provided for eliminating power to a load in the event of smoke detection. The system may comprise a device located at the appliance for detecting a signal from a smoke detector, and cutting power to the appliance only when the appliance is in use. The device may be synchronized with any standard smoke alarm signal to reduce the number of false positive shut-offs. The system may also comprise a smoke alarm hard-wired to a circuit breaker, for shutting off power to all appliances on a particular breaker upon receipt of a signal from the smoke alarm, and only when the appliances on the breaker are in use. The system may also have the ability to shut off one breaker, multiple breakers, or all breakers at different time increments to actively prevent and reduce the damages caused by fires.

Abstract: A pre-hung barn door hardware system is disclosed. The -hung barn door hardware system includes a rail having a plurality of rail holes disposed along a length of the rail; a plurality of spacers each of the plurality of spacers having a spacer hole; a track having a plurality of track holes disposed along the length of the track; a plurality of bolts, each of the plurality of bolts extending through one of the plurality of rail holes, a spacer hole in one of the plurality of spacers, and one of the plurality of track holes; and a plurality of nuts, each one of the plurality of nuts being coupled with a corresponding one of the plurality of bolts.

Abstract: A safety shut-off system and method are provided for eliminating power to a load in the event of smoke detection. The system may comprise a device located at the appliance for detecting a signal from a smoke detector, and cutting power to the appliance only when the appliance is in use. The device may be synchronized with any standard smoke alarm signal to reduce the number of false positive shut-offs. The system may also comprise a smoke alarm hard-wired to a circuit breaker, for shutting off power to all appliances on a particular breaker upon receipt of a signal from the smoke alarm, and only when the appliances on the breaker are in use. The system may also have the ability to shut off one breaker, multiple breakers, or all breakers at different time increments to actively prevent and reduce the damages caused by fires.

Abstract: A safety shut-off system and method for eliminating power to a load in the event of smoke detection. The system may comprise a device located at the appliance for detecting a signal from a smoke detector, and cutting power to the appliance only when the appliance is in use. The device may be synchronized with any standard smoke alarm signal to reduce the number of false positive shut-offs. The system may also comprise a smoke alarm hard-wired to a circuit breaker, for shutting off power to all appliances on a particular breaker upon receipt of a signal from the smoke alarm, and only when the appliances on the breaker are in use. The system may also have the ability to shut off one breaker, multiple breakers, or all breakers at different time increments to actively prevent and reduce the damages caused by fires.

Abstract: A safety shut-off system and method for eliminating power to a load in the event of smoke detection. The system may comprise a device located at the appliance for detecting a signal from a smoke detector, and cutting power to the appliance only when the appliance is in use. The device may be synchronized with any standard smoke alarm signal to reduce the number of false positive shut-offs. The system may also comprise a smoke alarm hard-wired to a circuit breaker, for shutting off power to all appliances on a particular breaker upon receipt of a signal from the smoke alarm, and only when the appliances on the breaker are in use. The system may also have the ability to shut off one breaker, multiple breakers, or all breakers at different time increments to actively prevent and reduce the damages caused by fires.