Patents by Inventor Che Hsin Lin

Che Hsin Lin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240075308
    Abstract: The present invention provides a plasma device for skin repair, which includes a plasma head, a power supply, a gas supply source, and a control box. The plasma head includes an inner sleeve and an outer sleeve which are sleeved together. The inner sleeve has a first bottom portion having several first through holes. The outer sleeve has a second bottom portion having several second through holes. A gap is formed between the first bottom portion and the second bottom portion. The power supply is configured to provide 13.56 MHz to 54 MHz radio frequency power to generate a discharge in the gap. The gas supply source is configured to provide reaction gas into the gap, and plasma is formed by the reaction gas under the discharge. The control box is configured to control operating parameters of the plasma head, the power supply, and the gas supply source.
    Type: Application
    Filed: August 28, 2023
    Publication date: March 7, 2024
    Applicant: Longyi Bio-Medical Technology Ltd.
    Inventors: Che-hsin LIN, Yao-hsien WANG
  • Patent number: 10895561
    Abstract: An embedding sensor module includes a cylinder and at least one flake sensor. A fluid tank is surrounded by the cylinder. The cylinder has a plurality of orifice connected to the fluid tank. The flake sensor is embedded in the fluid tank.
    Type: Grant
    Filed: December 15, 2017
    Date of Patent: January 19, 2021
    Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Jung-Hao Wang, Che-Hsin Lin, Wei-Sin Kao, Pai-Hao Wu, Chen-Hua Chu, Cheng-Hung San
  • Patent number: 10772210
    Abstract: A solution property sensor is provided and has: a substrate, a temperature sensing element, an electrical conductivity sensing element, a pH value sensing element, and a reference electrode. The solution property sensor utilizes different sensing elements to sense various solution properties, and all of these sensing elements can be electrically connected and fixed to conductive patterns on the same substrate, thereby facilitating mass production in the industry or reducing production difficulty.
    Type: Grant
    Filed: October 7, 2018
    Date of Patent: September 8, 2020
    Assignee: National Sun Yat-sen University
    Inventors: Che-hsin Lin, Wei-hsing Yen, Wei-sin Kao
  • Publication number: 20200113060
    Abstract: A solution property sensor is provided and has: a substrate, a temperature sensing element, an electrical conductivity sensing element, a pH value sensing element, and a reference electrode. The solution property sensor utilizes different sensing elements to sense various solution properties, and all of these sensing elements can be electrically connected and fixed to conductive patterns on the same substrate, thereby facilitating mass production in the industry or reducing production difficulty.
    Type: Application
    Filed: October 7, 2018
    Publication date: April 9, 2020
    Inventors: Che-hsin LIN, Wei-hsing YEN, Wei-sin KAO
  • Patent number: 10570365
    Abstract: An automatic cell isolation and collection system for sorting out target cells from a sample includes a crush module, a centrifuge module, a transport module, and a control unit. The centrifuge module includes centrifuge tubes and a magnetic mechanism providing a magnetically attractive force to at least one of the centrifuge tubes. The control unit electrically communicates with the crush module, the centrifuge module, and the transport module, and controls operation of the crush module, transport of the sample via the transport module after the sample is crushed by the crush module, centrifugation of the centrifuge module, and operation of the magnetic mechanism for providing the magnetically attractive force.
    Type: Grant
    Filed: December 21, 2017
    Date of Patent: February 25, 2020
    Assignee: Kaohsiung Medical University
    Inventors: Che-Hsin Lin, Yao-Hsien Wang, Chung-Hwan Chen, Je-Ken Chang, Mei-Ling Ho
  • Publication number: 20200033232
    Abstract: Provided is a device for rapidly isolating cells from tissue, comprising: a stirring and cutting member, having a rotary cutting tool, wherein same is driven by a motor so as to rotate to stir and cut tissue, and can inject digestive enzymes to accelerate decomposition of the tissue; and double-layered nested cups comprising an inner cup and an outer cup, used for accommodating and filtering solution of required cells, wherein a filter device of the inner cup screens out the required cells, and the outer cup collects the filtered solution.
    Type: Application
    Filed: September 29, 2016
    Publication date: January 30, 2020
    Applicant: KAOHSIUNG MEDICAL UNIVERSITY
    Inventors: Che-Hsin Lin, Yao-Hsien Wang, Chung-Hwan Chen, Je-Ken Chang, Mei-Ling Ho
  • Publication number: 20190187112
    Abstract: An embedding sensor module includes a cylinder and at least one flake sensor. A fluid tank is surrounded by the cylinder. The cylinder has a plurality of orifice connected to the fluid tank. The flake sensor is embedded in the fluid tank.
    Type: Application
    Filed: December 15, 2017
    Publication date: June 20, 2019
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Jung-Hao WANG, Che-Hsin LIN, Wei-Sin KAO, Pai-Hao WU, Chen-Hua CHU, Cheng-Hung SAN
  • Publication number: 20180328824
    Abstract: An automatic cell isolation and collection system for sorting out target cells from a sample includes a crush module, a centrifuge module, a transport module, and a control unit. The centrifuge module includes centrifuge tubes and a magnetic mechanism providing a magnetically attractive force to at least one of the centrifuge tubes. The control unit electrically communicates with the crush module, the centrifuge module, and the transport module, and controls operation of the crush module, transport of the sample via the transport module after the sample is crushed by the crush module, centrifugation of the centrifuge module, and operation of the magnetic mechanism for providing the magnetically attractive force.
    Type: Application
    Filed: December 21, 2017
    Publication date: November 15, 2018
    Applicant: Kaohsiung Medical University
    Inventors: Che-Hsin Lin, Yao-Hsien Wang, Chung-Hwan Chen, Je-Ken Chang, Mei-Ling Ho
  • Publication number: 20180274070
    Abstract: A biocompatible Ti-based alloy having a formula of TiaZrwTabSixSnyCoz is disclosed, wherein a is 40-44, b is 1-5 and the sum of w, x, y, z is 55. The alloy is amorphous. The alloy is applicable to manufacturing ultrafine powder which is used for additive manufacturing. The alloy is characterized in high glass forming ability, low toxicity, and high strength, and the powder thereof has low roughness and high circularity, and is suitable for implantable medical device.
    Type: Application
    Filed: October 24, 2017
    Publication date: September 27, 2018
    Inventors: Jason Shiang-Ching JANG, Chih-Ching HUANG, Che-Hsin LIN, Pei-Hua TSAI, Tsung-Hsiung LI
  • Patent number: 9146212
    Abstract: A thread-based microfluidic guiding system is provided and includes a substrate, two fiber threads arranged on the substrate in a cross manner. The two fiber threads are used as physical guiding pathways to guide a sample fluid and a buffer fluid, respectively. The two fiber threads have capillary action, so that the sample fluid, the buffer fluid or a mixture fluid thereof can flow along fiber surfaces of the two fiber threads, which can be pre-treated by plasma. The thread-based microfluidic guiding system of the present invention is different from recessed microfluidic channel structures, and can simplify system structure, lower manufacture cost, accelerate detection operation and enhance detection sensitivity.
    Type: Grant
    Filed: May 9, 2013
    Date of Patent: September 29, 2015
    Assignee: NATIONAL SUN YAT-SEN UNIVERSITY
    Inventors: Che-hsin Lin, Yi-chi Wei, Lung-min Fu, Yu-An Yang
  • Publication number: 20150168362
    Abstract: A microfluidic channel detection system for environmental or biomedical detection includes a chip having a first surface where a sensing region is located, a substrate having a recess for containing the chip, in which the first surface is exposed, a first inactive layer filling gaps between the chip and the substrate in the recess, so as to form a plane with the first surface of the chip, an electrical connection member electrically connected to the chip, a cover having a microfluidic channel and disposed on the plane. The flow path in the microfluidic channel is smooth, and further the measurement accuracy is improved via the plane formed by the first inactive layer and the first surface.
    Type: Application
    Filed: February 20, 2014
    Publication date: June 18, 2015
    Applicant: National Applied Research Laboratories
    Inventors: Che-Hsin LIN, Jun-Jie WANG, Ying-Zong JUANG, Hann-Huei TSAI, Hsin-Hao LIAO
  • Patent number: 8625195
    Abstract: An objective-type dark-field illumination device for a microfluidic channel is provided and includes an optical stop having a pair of symmetric curved slits used to adjust the optical path and inner numerical aperture of a dark-field light source generated by the device. The dark-field illumination can focus on a smaller spot to illuminate a sample in the microfluidic channel by matching a pin-hole combined with a transmitter objective lens. The optical path and smaller spot is advantageous to solve the problem of a traditional dark-field illumination that may generate background light noise scattered from inner walls of the microfluidic channel to lower the image contrast. Therefore, the signal or image resolution of capturing the scattered light and/or emitted fluorescent light emitted from the sample in the microfluidic channel can be enhanced. Meanwhile, the device can simultaneously excite and detect multiple fluorescent samples with different excited wavelengths in the microfluidic channel.
    Type: Grant
    Filed: August 5, 2010
    Date of Patent: January 7, 2014
    Assignee: National Sun Yat-Sen University
    Inventors: Che-hsin Lin, Shi-wei Lin, Jui-hung Hsu, Chih-han Chang
  • Publication number: 20130299352
    Abstract: A thread-based microfluidic guiding system is provided and includes a substrate, two fiber threads arranged on the substrate in a cross manner. The two fiber threads are used as physical guiding pathways to guide a sample fluid and a buffer fluid, respectively. The two fiber threads have capillary action, so that the sample fluid, the buffer fluid or a mixture fluid thereof can flow along fiber surfaces of the two fiber threads, which can be pre-treated by plasma. The thread-based microfluidic guiding system of the present invention is different from recessed microfluidic channel structures, and can simplify system structure, lower manufacture cost, accelerate detection operation and enhance detection sensitivity.
    Type: Application
    Filed: May 9, 2013
    Publication date: November 14, 2013
    Applicant: National Sun Yat-sen University
    Inventors: Che-hsin LIN, Yi-chi Wei, Lung-min Fu, Yu-An Yang
  • Patent number: 8025820
    Abstract: A method for manufacturing microlens comprises the steps of: coating a photosensitive polymer onto a first substrate to form a polymer film having a first surface in contact with the first substrate and a second surface; heating the polymer film; exposing the second surface of the polymer film to form a mold layer with at least one through hole; pressing and abutting the mold layer onto a second substrate and heating the photosensitive polymer within the mold layer to a temperature higher than a glass transition temperature of the photosensitive polymer for the photosensitive polymer to be melted and flow through the at least one through hole, attach onto the second substrate, and form at least one microlens on a surface of the second substrate; and performing an exposure to the at least one microlens and solidifying the at least one microlens.
    Type: Grant
    Filed: April 3, 2009
    Date of Patent: September 27, 2011
    Assignee: National Sun Yat-Sen University
    Inventors: Che-Hsin Lin, Shu-Ming Kuo
  • Publication number: 20110157692
    Abstract: An objective-type dark-field illumination device for a microfluidic channel is provided and includes an optical stop having a pair of symmetric curved slits used to adjust the optical path and inner numerical aperture of a dark-field light source generated by the device. The dark-field illumination can focus on a smaller spot to illuminate a sample in the microfluidic channel by matching a pin-hole combined with a transmitter objective lens. The optical path and smaller spot is advantageous to solve the problem of a traditional dark-field illumination that may generate background light noise scattered from inner walls of the microfluidic channel to lower the image contrast. Therefore, the signal or image resolution of capturing the scattered light and/or emitted fluorescent light emitted from the sample in the microfluidic channel can be enhanced. Meanwhile, the device can simultaneously excite and detect multiple fluorescent samples with different excited wavelengths in the microfluidic channel.
    Type: Application
    Filed: August 5, 2010
    Publication date: June 30, 2011
    Applicant: National Sun Yat-Sen University
    Inventors: CHE-HSIN LIN, Shi-wei Lin, Jui-hung Hsu, Chih-han Chang
  • Patent number: 7667197
    Abstract: The present invention relates to a mass analyzing apparatus, comprising a first metal electrode plate, a second metal electrode plate, an RF power supply, a reactant gas and a mass spectrometry. The second metal electrode plate is grounded. There is a gap between the first metal electrode plate and the second metal electrode plate. The RF power supply is electrically connected to the first metal electrode plate. Electric discharge is caused between the first metal electrode plate and the second metal electrode plate, so that the reactant gas becomes dissociation plasma. The dissociation plasma reacts with a gas analyte from a sample and then enters the mass spectrometry for a mass analysis. In addition, since the dissociation plasma is generated under low temperature and atmospheric pressure, the mass analyzing apparatus of the present invention is applicable for biological samples that need to be analyzed at a low temperature.
    Type: Grant
    Filed: July 17, 2007
    Date of Patent: February 23, 2010
    Assignee: National Sun Yat-Sen University
    Inventors: Che-Hsin Lin, Jen-Taie Shiea, Wei-Jen Hsu, Liang-Tsuen Chen
  • Publication number: 20090308525
    Abstract: A method for manufacturing microlens comprises the steps of: coating a photosensitive polymer onto a first substrate to form a polymer film having a first surface in contact with the first substrate and a second surface; heating the polymer film; exposing the second surface of the polymer film to form a mold layer with at least one through hole; pressing and abutting the mold layer onto a second substrate and heating the photosensitive polymer within the mold layer to a temperature higher than a glass transition temperature of the photosensitive polymer for the photosensitive polymer to be melted and flow through the at least one through hole, attach onto the second substrate, and form at least one microlens on a surface of the second substrate; and performing an exposure to the at least one microlens and solidifying the at least one microlens.
    Type: Application
    Filed: April 3, 2009
    Publication date: December 17, 2009
    Inventors: Che-Hsin LIN, Shu-Ming Kuo
  • Patent number: 7488516
    Abstract: A method for modification of glass-based microchannels, which uses liquid organic-based solution containing siloxane for the modification of microchannels on the glass substrate, such as quartz, boron glass, sodium glass, and the like, to form a solid film to isolate the glass surface of the microchannels from the environment. Therefore, the present invention can be applied for electrophoresis experiment, so that the operation causes no electrical-double-layer effects, and further eliminates the occurrence of electro-osmosis flow, thus the separation efficiency of electrophoresis chips is improved.
    Type: Grant
    Filed: January 20, 2004
    Date of Patent: February 10, 2009
    Assignee: National Cheng Kung University
    Inventors: Gwo Bin Lee, Che Hsin Lin, Shu Hui Chen
  • Publication number: 20080277579
    Abstract: The present invention relates to a mass analyzing apparatus, comprising a first metal electrode plate, a second metal electrode plate, an RF power supply, a reactant gas and a mass spectrometry. The second metal electrode plate is grounded. There is a gap between the first metal electrode plate and the second metal electrode plate. The RF power supply is electrically connected to the first metal electrode plate. Electric discharge is caused between the first metal electrode plate and the second metal electrode plate, so that the reactant gas becomes dissociation plasma. The dissociation plasma reacts with a gas analyte from a sample and then enters the mass spectrometry for a mass analysis. In addition, since the dissociation plasma is generated under low temperature and atmospheric pressure, the mass analyzing apparatus of the present invention is applicable for biological samples that need to be analyzed at a low temperature.
    Type: Application
    Filed: July 17, 2007
    Publication date: November 13, 2008
    Inventors: Che-Hsin LIN, Jen-Taie SHIEA, Wei-Jen HSU, Liang-Tsuen CHEN
  • Publication number: 20050274618
    Abstract: An assay chip includes a microchannel unit formed in a substrate. The microchannel unit includes a sample channel having inlet and outlet ends, a detection channel which intersects the sample channel and has an injection end and a recycle end on two opposite sides of the sample channel, respectively, and at least one light-exciting channel and at least one light-sensing channel disposed respectively adjacent to two opposite sides of the detection channel between the recycle end and the sample channel. A sensor unit includes first and second optical fibers inserted respectively into the light-exciting and light-sensing channels.
    Type: Application
    Filed: May 21, 2005
    Publication date: December 15, 2005
    Inventors: Gwo-Bin Lee, Che-Hsin Lin, Suz-Kai Hsiung