Patents by Inventor Che Hsin Lin
Che Hsin Lin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240075308Abstract: The present invention provides a plasma device for skin repair, which includes a plasma head, a power supply, a gas supply source, and a control box. The plasma head includes an inner sleeve and an outer sleeve which are sleeved together. The inner sleeve has a first bottom portion having several first through holes. The outer sleeve has a second bottom portion having several second through holes. A gap is formed between the first bottom portion and the second bottom portion. The power supply is configured to provide 13.56 MHz to 54 MHz radio frequency power to generate a discharge in the gap. The gas supply source is configured to provide reaction gas into the gap, and plasma is formed by the reaction gas under the discharge. The control box is configured to control operating parameters of the plasma head, the power supply, and the gas supply source.Type: ApplicationFiled: August 28, 2023Publication date: March 7, 2024Applicant: Longyi Bio-Medical Technology Ltd.Inventors: Che-hsin LIN, Yao-hsien WANG
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Patent number: 10895561Abstract: An embedding sensor module includes a cylinder and at least one flake sensor. A fluid tank is surrounded by the cylinder. The cylinder has a plurality of orifice connected to the fluid tank. The flake sensor is embedded in the fluid tank.Type: GrantFiled: December 15, 2017Date of Patent: January 19, 2021Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Jung-Hao Wang, Che-Hsin Lin, Wei-Sin Kao, Pai-Hao Wu, Chen-Hua Chu, Cheng-Hung San
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Patent number: 10772210Abstract: A solution property sensor is provided and has: a substrate, a temperature sensing element, an electrical conductivity sensing element, a pH value sensing element, and a reference electrode. The solution property sensor utilizes different sensing elements to sense various solution properties, and all of these sensing elements can be electrically connected and fixed to conductive patterns on the same substrate, thereby facilitating mass production in the industry or reducing production difficulty.Type: GrantFiled: October 7, 2018Date of Patent: September 8, 2020Assignee: National Sun Yat-sen UniversityInventors: Che-hsin Lin, Wei-hsing Yen, Wei-sin Kao
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Publication number: 20200113060Abstract: A solution property sensor is provided and has: a substrate, a temperature sensing element, an electrical conductivity sensing element, a pH value sensing element, and a reference electrode. The solution property sensor utilizes different sensing elements to sense various solution properties, and all of these sensing elements can be electrically connected and fixed to conductive patterns on the same substrate, thereby facilitating mass production in the industry or reducing production difficulty.Type: ApplicationFiled: October 7, 2018Publication date: April 9, 2020Inventors: Che-hsin LIN, Wei-hsing YEN, Wei-sin KAO
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Patent number: 10570365Abstract: An automatic cell isolation and collection system for sorting out target cells from a sample includes a crush module, a centrifuge module, a transport module, and a control unit. The centrifuge module includes centrifuge tubes and a magnetic mechanism providing a magnetically attractive force to at least one of the centrifuge tubes. The control unit electrically communicates with the crush module, the centrifuge module, and the transport module, and controls operation of the crush module, transport of the sample via the transport module after the sample is crushed by the crush module, centrifugation of the centrifuge module, and operation of the magnetic mechanism for providing the magnetically attractive force.Type: GrantFiled: December 21, 2017Date of Patent: February 25, 2020Assignee: Kaohsiung Medical UniversityInventors: Che-Hsin Lin, Yao-Hsien Wang, Chung-Hwan Chen, Je-Ken Chang, Mei-Ling Ho
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Publication number: 20200033232Abstract: Provided is a device for rapidly isolating cells from tissue, comprising: a stirring and cutting member, having a rotary cutting tool, wherein same is driven by a motor so as to rotate to stir and cut tissue, and can inject digestive enzymes to accelerate decomposition of the tissue; and double-layered nested cups comprising an inner cup and an outer cup, used for accommodating and filtering solution of required cells, wherein a filter device of the inner cup screens out the required cells, and the outer cup collects the filtered solution.Type: ApplicationFiled: September 29, 2016Publication date: January 30, 2020Applicant: KAOHSIUNG MEDICAL UNIVERSITYInventors: Che-Hsin Lin, Yao-Hsien Wang, Chung-Hwan Chen, Je-Ken Chang, Mei-Ling Ho
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Publication number: 20190187112Abstract: An embedding sensor module includes a cylinder and at least one flake sensor. A fluid tank is surrounded by the cylinder. The cylinder has a plurality of orifice connected to the fluid tank. The flake sensor is embedded in the fluid tank.Type: ApplicationFiled: December 15, 2017Publication date: June 20, 2019Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Jung-Hao WANG, Che-Hsin LIN, Wei-Sin KAO, Pai-Hao WU, Chen-Hua CHU, Cheng-Hung SAN
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Publication number: 20180328824Abstract: An automatic cell isolation and collection system for sorting out target cells from a sample includes a crush module, a centrifuge module, a transport module, and a control unit. The centrifuge module includes centrifuge tubes and a magnetic mechanism providing a magnetically attractive force to at least one of the centrifuge tubes. The control unit electrically communicates with the crush module, the centrifuge module, and the transport module, and controls operation of the crush module, transport of the sample via the transport module after the sample is crushed by the crush module, centrifugation of the centrifuge module, and operation of the magnetic mechanism for providing the magnetically attractive force.Type: ApplicationFiled: December 21, 2017Publication date: November 15, 2018Applicant: Kaohsiung Medical UniversityInventors: Che-Hsin Lin, Yao-Hsien Wang, Chung-Hwan Chen, Je-Ken Chang, Mei-Ling Ho
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Publication number: 20180274070Abstract: A biocompatible Ti-based alloy having a formula of TiaZrwTabSixSnyCoz is disclosed, wherein a is 40-44, b is 1-5 and the sum of w, x, y, z is 55. The alloy is amorphous. The alloy is applicable to manufacturing ultrafine powder which is used for additive manufacturing. The alloy is characterized in high glass forming ability, low toxicity, and high strength, and the powder thereof has low roughness and high circularity, and is suitable for implantable medical device.Type: ApplicationFiled: October 24, 2017Publication date: September 27, 2018Inventors: Jason Shiang-Ching JANG, Chih-Ching HUANG, Che-Hsin LIN, Pei-Hua TSAI, Tsung-Hsiung LI
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Patent number: 9146212Abstract: A thread-based microfluidic guiding system is provided and includes a substrate, two fiber threads arranged on the substrate in a cross manner. The two fiber threads are used as physical guiding pathways to guide a sample fluid and a buffer fluid, respectively. The two fiber threads have capillary action, so that the sample fluid, the buffer fluid or a mixture fluid thereof can flow along fiber surfaces of the two fiber threads, which can be pre-treated by plasma. The thread-based microfluidic guiding system of the present invention is different from recessed microfluidic channel structures, and can simplify system structure, lower manufacture cost, accelerate detection operation and enhance detection sensitivity.Type: GrantFiled: May 9, 2013Date of Patent: September 29, 2015Assignee: NATIONAL SUN YAT-SEN UNIVERSITYInventors: Che-hsin Lin, Yi-chi Wei, Lung-min Fu, Yu-An Yang
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Publication number: 20150168362Abstract: A microfluidic channel detection system for environmental or biomedical detection includes a chip having a first surface where a sensing region is located, a substrate having a recess for containing the chip, in which the first surface is exposed, a first inactive layer filling gaps between the chip and the substrate in the recess, so as to form a plane with the first surface of the chip, an electrical connection member electrically connected to the chip, a cover having a microfluidic channel and disposed on the plane. The flow path in the microfluidic channel is smooth, and further the measurement accuracy is improved via the plane formed by the first inactive layer and the first surface.Type: ApplicationFiled: February 20, 2014Publication date: June 18, 2015Applicant: National Applied Research LaboratoriesInventors: Che-Hsin LIN, Jun-Jie WANG, Ying-Zong JUANG, Hann-Huei TSAI, Hsin-Hao LIAO
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Patent number: 8625195Abstract: An objective-type dark-field illumination device for a microfluidic channel is provided and includes an optical stop having a pair of symmetric curved slits used to adjust the optical path and inner numerical aperture of a dark-field light source generated by the device. The dark-field illumination can focus on a smaller spot to illuminate a sample in the microfluidic channel by matching a pin-hole combined with a transmitter objective lens. The optical path and smaller spot is advantageous to solve the problem of a traditional dark-field illumination that may generate background light noise scattered from inner walls of the microfluidic channel to lower the image contrast. Therefore, the signal or image resolution of capturing the scattered light and/or emitted fluorescent light emitted from the sample in the microfluidic channel can be enhanced. Meanwhile, the device can simultaneously excite and detect multiple fluorescent samples with different excited wavelengths in the microfluidic channel.Type: GrantFiled: August 5, 2010Date of Patent: January 7, 2014Assignee: National Sun Yat-Sen UniversityInventors: Che-hsin Lin, Shi-wei Lin, Jui-hung Hsu, Chih-han Chang
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Publication number: 20130299352Abstract: A thread-based microfluidic guiding system is provided and includes a substrate, two fiber threads arranged on the substrate in a cross manner. The two fiber threads are used as physical guiding pathways to guide a sample fluid and a buffer fluid, respectively. The two fiber threads have capillary action, so that the sample fluid, the buffer fluid or a mixture fluid thereof can flow along fiber surfaces of the two fiber threads, which can be pre-treated by plasma. The thread-based microfluidic guiding system of the present invention is different from recessed microfluidic channel structures, and can simplify system structure, lower manufacture cost, accelerate detection operation and enhance detection sensitivity.Type: ApplicationFiled: May 9, 2013Publication date: November 14, 2013Applicant: National Sun Yat-sen UniversityInventors: Che-hsin LIN, Yi-chi Wei, Lung-min Fu, Yu-An Yang
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Patent number: 8025820Abstract: A method for manufacturing microlens comprises the steps of: coating a photosensitive polymer onto a first substrate to form a polymer film having a first surface in contact with the first substrate and a second surface; heating the polymer film; exposing the second surface of the polymer film to form a mold layer with at least one through hole; pressing and abutting the mold layer onto a second substrate and heating the photosensitive polymer within the mold layer to a temperature higher than a glass transition temperature of the photosensitive polymer for the photosensitive polymer to be melted and flow through the at least one through hole, attach onto the second substrate, and form at least one microlens on a surface of the second substrate; and performing an exposure to the at least one microlens and solidifying the at least one microlens.Type: GrantFiled: April 3, 2009Date of Patent: September 27, 2011Assignee: National Sun Yat-Sen UniversityInventors: Che-Hsin Lin, Shu-Ming Kuo
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Publication number: 20110157692Abstract: An objective-type dark-field illumination device for a microfluidic channel is provided and includes an optical stop having a pair of symmetric curved slits used to adjust the optical path and inner numerical aperture of a dark-field light source generated by the device. The dark-field illumination can focus on a smaller spot to illuminate a sample in the microfluidic channel by matching a pin-hole combined with a transmitter objective lens. The optical path and smaller spot is advantageous to solve the problem of a traditional dark-field illumination that may generate background light noise scattered from inner walls of the microfluidic channel to lower the image contrast. Therefore, the signal or image resolution of capturing the scattered light and/or emitted fluorescent light emitted from the sample in the microfluidic channel can be enhanced. Meanwhile, the device can simultaneously excite and detect multiple fluorescent samples with different excited wavelengths in the microfluidic channel.Type: ApplicationFiled: August 5, 2010Publication date: June 30, 2011Applicant: National Sun Yat-Sen UniversityInventors: CHE-HSIN LIN, Shi-wei Lin, Jui-hung Hsu, Chih-han Chang
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Patent number: 7667197Abstract: The present invention relates to a mass analyzing apparatus, comprising a first metal electrode plate, a second metal electrode plate, an RF power supply, a reactant gas and a mass spectrometry. The second metal electrode plate is grounded. There is a gap between the first metal electrode plate and the second metal electrode plate. The RF power supply is electrically connected to the first metal electrode plate. Electric discharge is caused between the first metal electrode plate and the second metal electrode plate, so that the reactant gas becomes dissociation plasma. The dissociation plasma reacts with a gas analyte from a sample and then enters the mass spectrometry for a mass analysis. In addition, since the dissociation plasma is generated under low temperature and atmospheric pressure, the mass analyzing apparatus of the present invention is applicable for biological samples that need to be analyzed at a low temperature.Type: GrantFiled: July 17, 2007Date of Patent: February 23, 2010Assignee: National Sun Yat-Sen UniversityInventors: Che-Hsin Lin, Jen-Taie Shiea, Wei-Jen Hsu, Liang-Tsuen Chen
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Publication number: 20090308525Abstract: A method for manufacturing microlens comprises the steps of: coating a photosensitive polymer onto a first substrate to form a polymer film having a first surface in contact with the first substrate and a second surface; heating the polymer film; exposing the second surface of the polymer film to form a mold layer with at least one through hole; pressing and abutting the mold layer onto a second substrate and heating the photosensitive polymer within the mold layer to a temperature higher than a glass transition temperature of the photosensitive polymer for the photosensitive polymer to be melted and flow through the at least one through hole, attach onto the second substrate, and form at least one microlens on a surface of the second substrate; and performing an exposure to the at least one microlens and solidifying the at least one microlens.Type: ApplicationFiled: April 3, 2009Publication date: December 17, 2009Inventors: Che-Hsin LIN, Shu-Ming Kuo
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Patent number: 7488516Abstract: A method for modification of glass-based microchannels, which uses liquid organic-based solution containing siloxane for the modification of microchannels on the glass substrate, such as quartz, boron glass, sodium glass, and the like, to form a solid film to isolate the glass surface of the microchannels from the environment. Therefore, the present invention can be applied for electrophoresis experiment, so that the operation causes no electrical-double-layer effects, and further eliminates the occurrence of electro-osmosis flow, thus the separation efficiency of electrophoresis chips is improved.Type: GrantFiled: January 20, 2004Date of Patent: February 10, 2009Assignee: National Cheng Kung UniversityInventors: Gwo Bin Lee, Che Hsin Lin, Shu Hui Chen
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Publication number: 20080277579Abstract: The present invention relates to a mass analyzing apparatus, comprising a first metal electrode plate, a second metal electrode plate, an RF power supply, a reactant gas and a mass spectrometry. The second metal electrode plate is grounded. There is a gap between the first metal electrode plate and the second metal electrode plate. The RF power supply is electrically connected to the first metal electrode plate. Electric discharge is caused between the first metal electrode plate and the second metal electrode plate, so that the reactant gas becomes dissociation plasma. The dissociation plasma reacts with a gas analyte from a sample and then enters the mass spectrometry for a mass analysis. In addition, since the dissociation plasma is generated under low temperature and atmospheric pressure, the mass analyzing apparatus of the present invention is applicable for biological samples that need to be analyzed at a low temperature.Type: ApplicationFiled: July 17, 2007Publication date: November 13, 2008Inventors: Che-Hsin LIN, Jen-Taie SHIEA, Wei-Jen HSU, Liang-Tsuen CHEN
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Publication number: 20050274618Abstract: An assay chip includes a microchannel unit formed in a substrate. The microchannel unit includes a sample channel having inlet and outlet ends, a detection channel which intersects the sample channel and has an injection end and a recycle end on two opposite sides of the sample channel, respectively, and at least one light-exciting channel and at least one light-sensing channel disposed respectively adjacent to two opposite sides of the detection channel between the recycle end and the sample channel. A sensor unit includes first and second optical fibers inserted respectively into the light-exciting and light-sensing channels.Type: ApplicationFiled: May 21, 2005Publication date: December 15, 2005Inventors: Gwo-Bin Lee, Che-Hsin Lin, Suz-Kai Hsiung