Patents by Inventor Che Lin KIM

Che Lin KIM has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cell line which is knock out the bmp receptor genes and a method of producing target proteins using the same
    Patent number: 11873326
    Abstract: The present invention relates to a transgenic CHO cell line in which the BMP receptor gene BMPRIA or BMPRII is knocked out. The BMP type I receptor BMPRIA or BMP type II receptor BMPRII gene which plays an important role in intracellular signal transduction in CHO cells is knocked out to prevent the activation of self concentration control pathway and the signal transduction mediated by BMP in CHO cells, so that the productivity of a target protein to be produced can be improved.
    Type: Grant
    Filed: August 30, 2019
    Date of Patent: January 16, 2024
    Inventors: Gyun-Min Lee, Che Lin Kim
  • CELL LINE WHICH IS KNOCK OUT THE BMP RECEPTOR GENES AND A METHOD OF PRODUCING TARGET PROTEINS USING THE SAME
    Publication number: 20200262883
    Abstract: The present invention relates to a transgenic CHO cell line in which the BMP receptor gene BMPRIA or BMPRII is knocked out. The BMP type I receptor BMPRIA or BMP type II receptor BMPRII gene which plays an important role in intracellular signal transduction in CHO cells is knocked out to prevent the activation of self concentration control pathway and the signal transduction mediated by BMP in CHO cells, so that the productivity of a target protein to be produced can be improved.
    Type: Application
    Filed: August 30, 2019
    Publication date: August 20, 2020
    Inventors: Gyun-Min LEE, Che Lin KIM